Effects of aflatoxin B1 on embryo fetal development in rabbits

Food and Chemical Toxicology

Volumn 43, Issue 4, 2005, Pages 607-615

  Wangikar, P B ^a   Dwivedi, P ^a   Sinha, N ^b   Sharma, A K ^a   Telang, A G ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Aflatoxin B1; Pathomorphology; Rabbit; Teratogenicity

Indexed keywords

AFLATOXIN B1; CORN OIL;

AGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BONE MALFORMATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DEGENERATION; DEVELOPMENTAL DISORDER; DISEASE SEVERITY; DISSOLUTION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO RESORPTION; FEMALE; FETUS; FETUS DEVELOPMENT; FETUS RESORPTION; FETUS WEIGHT; GESTATIONAL AGE; HEART MUSCLE CELL; HISTOPATHOLOGY; LENS DISEASE; LIVER DISEASE; MATERNAL MORTALITY; MEGAKARYOCYTE; METACARPAL BONE; MICROPHTHALMIA; MORPHOLOGY; NIDATION; NONHUMAN; ORBIT; OSSIFICATION; RABBIT; SKELETON MALFORMATION; SKULL DEFECT; TERATOGENICITY; TISSUE; TRICUSPID VALVE DISEASE; VERTEBRA MALFORMATION; VISCERA; ANIMAL; ANIMAL DISEASE; CONGENITAL MALFORMATION; DOSE RESPONSE; DRUG EFFECT; ORAL DRUG ADMINISTRATION; PREGNANCY;

ASPERGILLUS; ORYCTOLAGUS CUNICULUS; ZEA MAYS;

ABNORMALITIES; ADMINISTRATION, ORAL; AFLATOXIN B1; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC DEVELOPMENT; FEMALE; PREGNANCY; RABBITS;

EID: 13844256277     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.01.004     Document Type: Article

References (43)

1. Y.M. Abdulrazzaq, N. Osman, Z.M. Yousif, and O. Trad Morbidity in neonates of mothers who have ingested aflatoxins Ann. Trop. Paediatr. 24 2004 145 151
2. AOAC Official Method of Analysis 16th edition 1995 Assoc. Official Anal. Chem. Washington, DC
3. 1 in mice Acta Pharmacol. Toxicol. 43 1978 273 279
4. 1, ochratoxin A and zearalenone Acta. Vet. Scand. 22 1981 524 533
5. S. Beaudoin, P. Barbet, and F. Bargy Developmental Stages in the Rabbit Embryo: Guidelines to Choose an Appropriate Experimental Model Fetal Diagn. Ther. 18 2003 422 427
6. W.H. Butler The effect of maternal liver injury and dietary reduction on fetal growth in the rat Food. Cosmet. Toxicol. 9 1971 57 63
7. 1 on the pregnant rat British J. Exp. Pathol. 47 1966 242 247
8. Centers for Disease Control and Prevention (CDC) Outbreak of Aflatoxin Poisoning - Eastern and Central Provinces, Kenya, January-July 2004 MMWR 53 34 2004 790 793
9. J.D. Clark, A.V. Jain, R.C. Hatch, and A. Mahaffey Experimentally induced chronic aflatoxicosis in rabbits Am. J. Vet. Res. 41 1980 1841 1845
10. 1 on rat fetal lung lipids Biol. Neonates 33 1978 283 288
11. H.R. De Vries, S.M. Maxwell, and R.G. Hendrickse Foetal and neonatal exposure to aflatoxins Acta Paediatr. Scand. 78 1989 373 378
12. D.W. Denning, R. Allen, A.P. Wilkinson, and M.R. Morgan Transplacental transfer of aflatoxin in humans Carcinogenesis 11 1990 1033 1035
13. J.A. Dipaolo, J. Ellis, and H.E. Erwin Teratogenic response by hamsters, rats and mice to aflatoxin Nature 215 1967 638 669
14. Dwivedi, P., Sharma, A.K., Telang, A.G., 2004. NATP-CGP project on "Ochratoxicosis in animals with special reference to teratogenicity, diagnosis and ameliorative measures". Annual report, 2004, Division of Pathology, IVRI, Izatnagar-243 122, submitted to NATP-ICAR, New Delhi
15. R.H. Foote, and E.W. Carney The rabbit as a model for reproductive and developmental toxicity studies Reprod. Toxicol. 14 2000 477 493
16. 1 in the rodent embryo in vitro: Contribution of exogenous biotransformation system to toxicity Teratology 37 1988 101 111
17. Y. Gong, A. Hounsa, S. Egal, P.C. Turner, A.E. Sutcliffe, A.J. Hall, K. Cardwell, and C.P. Wild Postweaning exposure to aflatoxin results in impaired child growth: a longitudinal study in Benin, West Africa Environ. Health Perspect. 112 2004 1334 1338
18. M.S. Hoseyni Risk assessment of aflatoxin. III. Modelling the relative risk of hepatocellular carcinoma Risk Anal. 12 1992 123 128
19. 1-DNA adducts in human placenta and cord blood Cancer Res. 53 1993 1278 1280
20. H.S. Hussein, and J.M. Brasel Toxicity, metabolism and impact of mycotoxins on human and animals Toxicology 167 2001 101 134
21. T.R. Irvin, A.L.S. Poorniiyer, E.K. Stevens, and J.E. Martin Parental toxicity of aflatoxins: application of mammalian cell culture systems to characterize the developmental toxicity of aflatoxins mycotoxins Cancer Health 167 1991 82
22. F.E. Jonsyn, S.M. Maxwell, and R.G. Hendrickse Human fetal exposure to ochratoxin A and aflatoxins Ann. Trop. Paediatr. 15 1995 3 9
23. 1 on early embryonic stages of chick Gallus domesticus cultured in vitro Ind. J. Expt. Biol. 19 1981 528 531
24. E. Le Breton, C. Frayssinet, C. Lafarg, and A.M. De Recondo Aflatoxin. Mechanisme de l'action Food. Cosmet. Toxicol. 2 1964 675 677
25. K. Makarananda, U. Pengpan, M. Srisakulthong, K. Yoovathaworn, and K. Sriwatanakul Monitoring of aflatoxin exposure by biomarkers J. Toxicol. Sci. 23 1998 155 159
26. S.M. Maxwell, J.B. Familusi, O. Sodeinde, M.C. Chan, and R.G. Hendrickse Detection of naphthols and aflatoxins in Nigerian cord blood Ann. Trop. Paedatr. 14 1994 3 5
27. K. Mayura, M.A. Abdel-Wahhab, K.S. McKeinzie, A.B. Sarr, J.F. Edwards, K. Naquib, and T.D. Phillips Prevention of maternal and developmental toxicity in rats via dietary inclusion of common aflatoxin sorbents: potential for hidden risks Toxicol. Sci. 41 1998 175 182
28. Mir, M.S., 1998. Studies on pathology and immunology of ochratoxin A induced toxicosis and its interaction with Pasteurella multocida infection in rabbits. M.V.Sc. Thesis, I.V.R.I., Izatnagar
29. R. Montesano, P. Hainaut, and C.P. Wild Hepatocellular carcinoma: from gene to public health J. Natl. Cancer Inst. 89 1997 1844 1851
30. G. Reddy, and D.G.K. Rao Teratological effects of aflatoxin in rabbits Ind. Vet. J. 78 2001 900 902
31. T.V. Reddy, L. Vishwanathan, and T.A. Venkitasubramanian High aflatoxin production on a chemically defined medium Appl. Microbiol. 22 1971 393 396
32. R.E. Schmidt, and R.J. Panciera Effects of aflatoxin on pregnant hamsters and hamster fetuses J. Comp. Pathol. 90 1980 339 347
33. A. Sharma, and R. Sahai Teratological effects of aflatoxin on rats (Rattus novegocus) Ind. J. Anim. Res. 21 1 1987 35 40
34. K.P. Singh, and R. Singh Aflatoxicosis in broiler rabbits Ind. J. Vet. Pathol. 5 2 1998 35 39
35. K.P. Singh, Y.P. Singh, R. Singh, A.P. Pandey, and P.N. Khanna Aflatoxicosis in Angora rabbits Ind. J. Vet. Pathol. 17 2 1993 103 105
36. G.W. Snedecor, and W.G. Cochran Statistical Methods sixth ed. 1968 Oxford and IBH Publishing Company pp. 215-260
37. F. Trail, N. Mahanthi, and J. Linz Molecular biology of aflatoxin biosynthesis Microbiol. Reading 141 4 1995 755 765
38. P.B. Wangikar, P. Dwivedi, A.K. Sharma, A.G. Telang, and G.S. Bisht Haemato-biochemical changes in experimental ochratoxicosis and aflatoxicosis alone and in combination in pregnant rabbits Ind. J. Vet. Pathol. 28 1 2004 64 67
39. 1. I. Maternal toxicity and fetal anomalies Birth Defects Research Part B: Developmental and Reproductive Toxicity 71 6 2004 343 351
40. 1. II. Histopathological features of teratological anomalies induced in fetuses Birth Defects Research Part B: Developmental and Reproductive Toxicity 71 6 2004 352 358
41. C.P. Wild, and P.C. Turner The toxicology of aflatoxins as a basis for public health decisions Mutagenesis 17 2002 471 481
42. J.G. Wilson Methods for administering agents and detecting malformations in experimental animals J.G. Wilson J. Warkany Teratology Principles and Techniques 1965 Chicago University Press 262 277
43. World Health Organization, 1993. International Agency for Research on Cancer (IARC), Monographs on evaluation of carcinogenic risks to humans