Tryptanthrin inhibits angiogenesis by targeting the VEGFR2-mediated ERK1/2 signalling pathway

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Liao, Xuemei ^a,c   Zhou, Xuelin ^a   Mak, Nai Ki ^b   Leung, Kwok Nam ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 1; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR B; TRYPTANTHRIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG STRUCTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MICROVASCULAR ENDOTHELIAL CELL; MIGRATION INHIBITION; MOLECULAR DOCKING; MOUSE; NONHUMAN;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL LINE; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; ENDOTHELIAL CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; NEOVASCULARIZATION, PATHOLOGIC; QUINAZOLINES; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; WOUND HEALING;

EID: 84892777102     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082294     Document Type: Article

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