Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay

British Journal of Pharmacology

Volumn 138, Issue 2, 2003, Pages 377-385

  Cattaneo, Maria Grazia ^a   Pola, Sandra ^a   Dehò, Valeria ^a   Sanguini, Anna Maria ^b   Vicentini, Lucia Maria ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Schwarz Pharma SpA   (Italy)

Author keywords

Angiogenesis; Cell signalling; Human endothelial cells; In vivo neovascularization; Matrigel; Prostaglandins

Indexed keywords

8 BROMO CYCLIC AMP; ACIDIC FIBROBLAST GROWTH FACTOR; ADENYLATE CYCLASE; ALCOHOL; ANGIOGENESIS INHIBITOR; BASIC FIBROBLAST GROWTH FACTOR; BUTAPROST; CYCLIC AMP; FIBRONECTIN; FORSKOLIN; MATRIGEL; MESSENGER RNA; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1; PROSTAVASIN; SULPROSTONE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CAPILLARY; CELL GROWTH; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; DIABETIC RETINOPATHY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PERIPHERAL VASCULAR DISEASE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLID TUMOR; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ALPHA-CYCLODEXTRINS; ALPROSTADIL; ANIMALS; CELL DIVISION; CELL MOVEMENT; COLLAGEN; CYCLIC AMP; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; FEMALE; HUMANS; LAMININ; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEOGLYCANS; RECEPTORS, PROSTAGLANDIN E; TUMOR CELLS, CULTURED; UMBILICAL VEINS;

EID: 0037275772     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705051     Document Type: Article

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