Cell differentiation and apoptosis of monocytic and promyelocytic leukemia cells (U-937 and HL-60) by tryptanthrin, an active ingredient of Polygonum tinctorium Lour.

Pathology International

Volumn 51, Issue 5, 2001, Pages 315-325

  Kimoto, Tetsuo ^a   Hino, Keiko ^a   Koya Miyata, Satomi ^a   Yamamoto, Yukiko ^a   Takeuchi, Makoto ^a   Nishizaki, Yasushi ^a   Micallef, Mark J ^a   Ushio, Shimpei ^a   Iwaki, Kanso ^a   Ikeda, Masao ^a   Kurimoto, Masashi ^a  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

Anti tumor activity; Apoptosis; Cell differentiation; Polygonum tinctorium Lour.; Tryptanthrin

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DIMETHYL SULFOXIDE; FAS ANTIGEN; POLYGONUM TINCTORIUM EXTRACT; TRYPTANTHRIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL VACUOLE; CYTOTOXICITY; DRUG POTENCY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MONOCYTIC LEUKEMIA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

ANTIGENS, CD; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CELL DIVISION; CELL NUCLEUS; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERASES; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; NITROBLUE TETRAZOLIUM; PHAGOCYTOSIS; QUINAZOLINES; U937 CELLS;

EID: 0034950115     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2001.01204.x     Document Type: Article

References (25)

1. Cytotoxic effects of substances in Indigo plants (Polygonum tinctorium Lour.) on malignant tumor cells
2. Protection by Indigo plants (Polygonum tinctorium Lour.) against renal oxidative damage in mice treated with ferric nitrilotriacetate
3. Isolation of antifungal principle Tryptanthrin from Strobilanthes cusia O. Kuntze
4. The antimicrobial specificity of Tryptanthrin
5. Isolation of an antidermatophytic, Tryptanthrin, from Indigo plants, Polygonum tinctorium and Isatis tinctoria
6. Stoffwechselprodukte von mikroorganismen, 156. Mitteilung synthese und biosynthese substituierter tryptanthrin
7. Insecticidal and fungicidal compounds from Isatis tinctoria
8. Establishment and characterization of a human histocytic lymphoma cell line (U-937)
9. Induction of morphological and functional differentiation of human promyelocytic leukemia cells (HL-60) by compounds which induce differentiation of murine leukemia cells
10. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
11. Differentiation of WEHI-3B D+ monomyelocytic leukemia cells by retinoic acid and aclacinomycin A
12. 3,5,3′-triiodo-L-thyronine potentiates all-trans-retinoic-acid-induced apoptosis during differentiation of the promyeloleukemic cell HL-60
13. Esterases in human leukocytes
14. Cytochemical identification of monocytes and granulocytes
15. Proteolytic cleavage during chemotherapy induced apoptosis
16. Specific proteolytic cleavage of poly (ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
17. Ice-related in apoptosis
18. Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases
19. Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis
20. Establishment and characterization of a granulocytic subclone (UM 384) from the monoblastic cell line U-937
21. Tryptanthrins: A novel class of agonists of the aryl hydrocarbon receptor
22. Mitochondrial permeability transition triggers lymphocyte apoptosis
23. Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential
24. Molecular characterization of mitochondrial apoptosis-inducing factor
25. Human ICE/CED-3 protease nomenclature