Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo

Journal of Ethnopharmacology

Volumn 137, Issue 1, 2011, Pages 64-69

  Chan, Judy Yuet Wa ^a,b   Koon, Johnny Chi Man ^b   Liu, Xiaozhou ^a   Detmar, Michael ^c   Yu, Biao ^d   Kong, Siu Kai ^b   Fung, Kwok Pui ^a,b  

^a Prince of Wales Hospital   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c ETH ZURICH   (Switzerland)

^d SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Anti angiogenesis; Human microvascular endothelial cells; Vascular endothelial growth factor; Zebrafish

Indexed keywords

POLYPHYLLIN D; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MEDICINAL PLANT; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PARIS POLYPHYLLA; ZEBRA FISH;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DIOSGENIN; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; EMBRYO, NONMAMMALIAN; ENDOTHELIAL CELLS; HUMANS; LILIACEAE; NEOVASCULARIZATION, PHYSIOLOGIC; PLANTS, MEDICINAL; TIME FACTORS; ZEBRAFISH;

ANIMALIA; DANIO RERIO; PARIS POLYPHYLLA;

EID: 80052038008     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.021     Document Type: Article

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