Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cells

Bioconjugate Chemistry

Volumn 25, Issue 1, 2014, Pages 43-51

  Kim, Jayoung ^a   Sunshine, Joel C ^a   Green, Jordan J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DISEASES; ESTERS; GENE TRANSFER; GENES; MOLECULAR WEIGHT;

AMINO ESTERS; BASE POLYMERS; CAVEOLAE; CELLULAR UPTAKE; END GROUPS; GENE DELIVERY; HUMAN BREAST CANCER CELLS; POLYMER STRUCTURE; POLYPLEXES; TRIPLE NEGATIVE;

MOLECULAR BIOLOGY;

1 (3 AMINOPROPYL) 4 METHYLPIPERAZINE; 2 (3 AMINOPROPYLAMINO) ETHANOL; ANTINEOPLASTIC AGENT; CHLORPROMAZINE; CLATHRIN; GENISTEIN; POLY(1,4 BUTANEDIOL DIACRYLATE CO 4 AMINO 1 BUTANOL); POLY(BETA AMINO ESTER) DERIVATIVE; POLYMER; UNCLASSIFIED DRUG; WORTMANNIN; NANOPARTICLE; POLY(BETA-AMINO ESTER);

ARTICLE; BREAST CANCER; CANCER CELL; CAVEOLA; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ENDOCYTOSIS; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDRODYNAMICS; INTERNALIZATION; MOLECULAR WEIGHT; PARTICLE SIZE; ZETA POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; SURFACE PROPERTY; TUMOR CELL CULTURE;

CAVEOLAE; ENDOCYTOSIS; HUMANS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NANOPARTICLES; PARTICLE SIZE; POLYMERS; SURFACE PROPERTIES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 84892760552     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc4002322     Document Type: Article

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