Influence of macromer molecular weight and chemistry on poly(β-amino ester) network properties and initial cell interactions

Journal of Biomedical Materials Research - Part A

Volumn 85, Issue 3, 2008, Pages 731-741

  Brey, Darren M ^a   Erickson, Isaac ^a   Burdick, Jason A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Degradable; Photopolymerization; Poly( amino ester); Polymers; Tissue engineering

Indexed keywords

BIODEGRADABLE POLYMERS; CROSSLINKING; ELASTIC MODULI; MACROMOLECULES; MOLECULAR WEIGHT; PHOTOPOLYMERIZATION; TISSUE ENGINEERING;

BIOLOGICAL APPLICATIONS; DIACRYLATES; MACROMERS;

POLYESTERS;

ACRYLIC ACID DERIVATIVE; AMINE; AMINO ACID DERIVATIVE; ESTER DERIVATIVE; POLYMER;

ARTICLE; CELL INTERACTION; COMPRESSIVE STRENGTH; CROSS LINKING; DEGRADATION; DENSITY; MOLECULAR WEIGHT; TENSILE STRENGTH;

ANIMALS; CELL ADHESION; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; ESTERS; HUMANS; MOLECULAR WEIGHT; OSTEOBLASTS; POLYMERS;

EID: 43049087101     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31494     Document Type: Article

References (35)

1. Anseth KS, Goodner MD, Reill MA, Kannurpatti AR, Newman SM, Bowman CN. The influence of comonomer composition on dimethacrylate resin properties for dental composites. J Dent Res 1996;75:1607-1612.
2. Hillwest JL, Chowdhury SM, Sawhney AS, Pathak CP, Dunn RC, Hubbell JA. Prevention of postoperative adhesions in the rat by in-situ photopolymerization of bioresorbable hydrogel barriers. Obstet Gynecol 1994;83:59-64.
3. Anseth KS, Burdick JA. New directions in photopolymerizable biomaterials. Mrs Bull 2002;27:130-136.
4. Chung C, Mesa J, Miller GJ, Randolph MA, Gill TJ, Burdick JA. Effects of auricular chondrocyte expansion on neocartilage formation in photocrosslinked hyaluronic acid networks. Tissue Eng 2006;12:2665-2673.
5. Chung C, Mesa J, Randolph MA, Yaremchuk M, Burdick JA. Influence of gel properties on neocartilage formation by auricular chondrocytes photoencapsulated in hyaluronic acid networks. J Biomed Mater Res 2006;77A:518-525.
6. Elisseeff J, McIntosh W, Anseth K, Riley S, Ragan P, Langer R. Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks. J Biomed Mater Res 2000;51:164-171.
7. Fisher JP, Dean D, Engel PS, Mikos AG. Photoinitiated polymerization of biomaterials. Annu Rev Mater Res 2001;31:171-181.
8. Leach JB, Bivens KA, Patrick CW, Schmidt CE. Photocrosslinked hyaluronic acid hydrogels: Natural, biodegradable tissue engineering scaffolds. Biotechnol Bioeng 2003;82:578-589.
9. Nguyen KT, West JL. Photopolymerizable hydrogels for tissue engineering applications. Biomaterials 2002;23:4307-4314.
10. Smeds KA, Grinstaff MW. Photocrosslinkable polysaccharides for in situ hydrogel formation. J Biomed Mater Res 2001;54:115-121.
11. Anseth KS, Metters AT, Bryant SJ, Martens PJ, Elisseeff JH, Bowman CN. In situ forming degradable networks and their application in tissue engineering and drug delivery. J Control Rel 2002;78:199-209.
12. Burdick JA, Peterson AJ, Anseth KS. Conversion and temperature profiles during the photoinitiated polymerization of thick orthopaedic biomaterials. Biomaterials 2001;22:1779-1786.
13. Beebe DJ, Moore JS, Yu Q, Liu RH, Kraft ML, Jo BH, Devadoss C. Microfluidic tectonics: A comprehensive construction platform for microfluidic systems. Proc Natl Acad Sci USA 2000;97:13488-13493.
14. Albrecht DR, Underhill GH, Wassermann TB, Sah RL, Bhatia SN. Probing the role of multicellular organization in three-dimensional microenvironments. Nat Methods 2006;3:369-375.
15. Khademhosseini A, Eng G, Yeh J, Fukuda J, Blumling J III, Langer R, Burdick JA. Micromolding of photocrosslinkable hyaluronic acid for cell encapsulation and entrapment. J Biomed Mater Res 2006;79A:522-532.
16. Burg KJL, Porter S, Kellam JF. Biomaterial developments for bone tissue engineering. Biomaterials 2000;21:2347-2359.
17. Discher DE, Janmey P, Wang YL. Tissue cells feel and respond to the stiffness of their substrate. Science 2005;310:1139-1143.
18. Burdick JA, Anseth KS. Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 2002;23:4315-4323.
19. Hern DL, Hubbell JA. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J Biomed Mater Res 1998;39:266-276.
20. Burdick JA, Chung C, Jia XQ, Randolph MA, Langer R. Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks. Biomacromolecules 2005;6:386-391.
21. Fisher JP, Holland TA, Dean D, Engel PS, Mikos AG. Synthesis and properties of photocross-linked poly(propylene fumarate) scaffolds. J Biomater Sci Polym Edn 2001;12:673-687.
22. Anseth KS, Shastri VR, Langer R. Photopolymerizable degradable polyanhydrides with osteocompatibility. Nat Biotechnol 1999;17:156-159.
23. Mann BK, Gobin AS, Tsai AT, Schmedlen RH, West JL. Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: Synthetic ECM analogs for tissue engineering. Biomaterials 2001;22:3045-3051.
24. Burdick JA, Mason MN, Hinman AD, Thorne K, Anseth KS. Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. J Control Rel 2002;83:53-63.
25. Sawhney AS, Pathak CP, Hubbell JA. Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly (alpha-hydroxy acid) diacrylate macromers. Macromolecules 1993;26:581-587.
26. Lynn DM, Langer R. Degradable poly(beta-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA. J Am Chem Soc 2000;122:10761-10768.
27. Akinc A, Lynn DM, Anderson DG, Langer R. Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. J Am Chem Soc 2003;125:5316-5323.
28. Anderson DG, Tweedie CA, Hossain N, Navarro SM, Brey DM, Van Vliet KJ, Langer R, Burdick JA. A combinatorial library of photocrosslinkable and degradable materials. Adv Mater 2006;18:2614-2618.
29. Soltz MA, Ateshian GA. Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. J Biomech 1998;31:927-934.
30. Agrawal CM, Ray RB. Biodegradable polymeric scaffolds for musculoskeletal tissue engineering. J Biomed Mater Res 2001;55:141-150.
31. Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell 2006;126:677-689.
32. Langer R. Drug delivery and targeting. Nature 1998;392:5-10.
33. Langer R, Peppas NA. Advances in biomaterials, drug delivery, and bionanotechnology. Aiche J 2003;49:2990-3006.
34. Bryant SJ, Anseth KS. Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels. J Biomed Mater Res 2002;59:63-72.
35. Miller MD. Review of Orthopaedics. Philadelphia: Saunders; 2004. 7004 p.