-
1
-
-
0035496104
-
APC, Signal transduction and genetic instability in colorectal cancer
-
doi: 10.1038/35094067. PubMed: 11900252
-
Fodde R, Smits R, Clevers H (2001) APC, Signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 1: 55-67. doi: 10.1038/35094067. PubMed: 11900252.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
2
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
doi:10.1016/S0092-8674(00)81333-1. PubMed: 8861899
-
Kinzler KW, Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170. doi:10.1016/S0092-8674(00)81333-1. PubMed: 8861899.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
3
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
doi:10.1016/S0092-8674(00)00122-7. PubMed: 11057903
-
Bienz M, Clevers H (2000) Linking colorectal cancer to Wnt signaling. Cell 103: 311-320. doi:10.1016/S0092-8674(00)00122-7. PubMed: 11057903.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
4
-
-
30644458570
-
Balancing cell adhesion and Wnt signaling, the key role of â-catenin
-
doi:10.1016/j.gde.2005.12.007. PubMed: 16377174
-
Brembeck FH, Rosário M, Birchmeier W (2006) Balancing cell adhesion and Wnt signaling, the key role of â-catenin. Curr Opin Genet Dev 16: 51-59. doi:10.1016/j.gde.2005.12.007. PubMed: 16377174.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 51-59
-
-
Brembeck, F.H.1
Rosário, M.2
Birchmeier, W.3
-
5
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
doi:10.1101/gad.11.24.3286. PubMed: 9407023
-
Cadigan KM, Nusse R (1997) Wnt signaling: a common theme in animal development. Genes Dev 11: 3286-3305. doi:10.1101/gad.11.24.3286. PubMed: 9407023.
-
(1997)
Genes Dev
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
6
-
-
0034053069
-
Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus
-
doi:10.1126/science.287.5458.1606. PubMed: 10733430
-
Peifer M, Polakis P (2000) Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 287: 1606-1609. doi:10.1126/science.287. 5458.1606. PubMed: 10733430.
-
(2000)
Science
, vol.287
, pp. 1606-1609
-
-
Peifer, M.1
Polakis, P.2
-
7
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
doi:10.1126/science.289.5482.1194. PubMed: 10947987
-
Kawasaki Y, Senda T, Ishidate T, Koyama R, Morishita T et al. (2000) Asef, a link between the tumor suppressor APC and G-protein signaling. Science 289: 1194-1197. doi:10.1126/science.289.5482.1194. PubMed: 10947987.
-
(2000)
Science
, vol.289
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
-
8
-
-
36849095162
-
Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42
-
doi:10.1038/sj.onc.1210574. PubMed: 17599059
-
Kawasaki Y, Sagara M, Shibata Y, Shirouzu M, Yokoyama S et al. (2007) Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. Oncogene 26: 7620-7627. doi:10.1038/sj.onc. 1210574. PubMed: 17599059.
-
(2007)
Oncogene
, vol.26
, pp. 7620-7627
-
-
Kawasaki, Y.1
Sagara, M.2
Shibata, Y.3
Shirouzu, M.4
Yokoyama, S.5
-
9
-
-
33846151992
-
Asef is Cdc42-specific guanine nucleotide exchange factor
-
PubMed: 17214551
-
Gotthardt K, Ahmadian MR (2007) Asef is Cdc42-specific guanine nucleotide exchange factor. Biol Chem 388: 67-71. PubMed: 17214551.
-
(2007)
Biol Chem
, vol.388
, pp. 67-71
-
-
Gotthardt, K.1
Ahmadian, M.R.2
-
10
-
-
0037341566
-
Mutated APC and Asef are involved in the migration of colorectal tumor cells
-
doi:10.1038/ncb937. PubMed: 12598901
-
Kawasaki Y, Sato R, Akiyama T (2003) Mutated APC and Asef are involved in the migration of colorectal tumor cells. Nat Cell Biol 5: 211-215. doi:10.1038/ncb937. PubMed: 12598901.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 211-215
-
-
Kawasaki, Y.1
Sato, R.2
Akiyama, T.3
-
12
-
-
33846931753
-
Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element
-
doi:10.1128/MCB. 01608-06. PubMed: 17145773
-
Hamann MJ, Lubking CM, Luchini DN, Billadeau DD (2007) Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. Mol Cell Biol 27: 1380-1393. doi:10.1128/MCB. 01608-06. PubMed: 17145773.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1380-1393
-
-
Hamann, M.J.1
Lubking, C.M.2
Luchini, D.N.3
Billadeau, D.D.4
-
13
-
-
74049123198
-
The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis
-
doi:10.1074/jbc.M109.040691. PubMed: 19897489
-
Kawasaki Y, Jigami T, Furukawa S, Sagara M, Echizen K et al. (2010) The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis. J Biol Chem 285: 1199-1207. doi:10.1074/jbc.M109. 040691. PubMed: 19897489.
-
(2010)
J Biol Chem
, vol.285
, pp. 1199-1207
-
-
Kawasaki, Y.1
Jigami, T.2
Furukawa, S.3
Sagara, M.4
Echizen, K.5
-
14
-
-
0032525964
-
LIN-12/Notch signaling: Lessons from worms and flies
-
doi:10.1101/gad.12.12.1751. PubMed: 9637676
-
Greenwald I (1998) LIN-12/Notch signaling: lessons from worms and flies. Genes Dev 12: 1751-1762. doi:10.1101/gad.12.12.1751. PubMed: 9637676.
-
(1998)
Genes Dev
, vol.12
, pp. 1751-1762
-
-
Greenwald, I.1
-
15
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
doi:10.1126/science.284.5415.770. PubMed: 10221902
-
Artavanis-Tsakonas S, Rand MD, Lake RJ (1999) Notch signaling: cell fate control and signal integration in development. Science 284: 770-776. doi:10.1126/science.284.5415.770. PubMed: 10221902.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
16
-
-
0037376416
-
An overview of the Notch signaling pathway
-
doi:10.1016/S1084-9521(02)00179-9. PubMed: 12651094
-
Baron M (2003) An overview of the Notch signaling pathway. Semin Cell Dev Biol 14: 113-119. doi:10.1016/S1084-9521(02)00179-9. PubMed: 12651094.
-
(2003)
Semin Cell Dev Biol
, vol.14
, pp. 113-119
-
-
Baron, M.1
-
17
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, IIagan M (2009) The canonical Notch signaling pathway: Unfolding the activation mechanism. Cell 137: 216-233
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.I.M.1
-
18
-
-
20544447734
-
Notch signals control the fate of immature progenitor cells in the intestine
-
doi:10.1038/nature03589. PubMed: 15959516
-
Fre S, Huyghe M, Mourikis P, Robine S, Louvard D et al. (2005) Notch signals control the fate of immature progenitor cells in the intestine. Nature 435: 964-968. doi:10.1038/nature03589. PubMed: 15959516.
-
(2005)
Nature
, vol.435
, pp. 964-968
-
-
Fre, S.1
Huyghe, M.2
Mourikis, P.3
Robine, S.4
Louvard, D.5
-
19
-
-
0242456129
-
Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
-
doi:10.1038/sj.onc.1206758. PubMed: 14528285
-
Nickoloff BJ, Osborne BA, Miele L (2003) Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene 22: 6598-6608. doi:10.1038/sj.onc.1206758. PubMed: 14528285.
-
(2003)
Oncogene
, vol.22
, pp. 6598-6608
-
-
Nickoloff, B.J.1
Osborne, B.A.2
Miele, L.3
-
20
-
-
79955460636
-
Notch signalling in solid tumors: A little bit of everything but not all the time
-
Ranganathan P, Weaver K, Capobianco AJ (2010) Notch signalling in solid tumors: a little bit of everything but not all the time. Nat Rev Cancer 11: 338-351.
-
(2010)
Nat Rev Cancer
, vol.11
, pp. 338-351
-
-
Ranganathan, P.1
Weaver, K.2
Capobianco, A.J.3
-
21
-
-
20544460148
-
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
doi: 10.1038/nature03659. PubMed: 15959515
-
van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M et al. (2005) Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435: 959-963. doi: 10.1038/nature03659. PubMed: 15959515.
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
-
22
-
-
37349088615
-
γ-secretase inhibitor enhances taxane-induced mitotic arrest and apoptosis in colon cancer cells
-
doi: 10.1053/j.gastro.2007.10.008. PubMed: 18166351
-
Akiyoshi T, Nakamura M, Yanai K, Nagai S, Wada J et al. (2008) γ-secretase inhibitor enhances taxane-induced mitotic arrest and apoptosis in colon cancer cells. Gastroenterology 134: 131-144. doi: 10.1053/j.gastro. 2007.10.008. PubMed: 18166351.
-
(2008)
Gastroenterology
, vol.134
, pp. 131-144
-
-
Akiyoshi, T.1
Nakamura, M.2
Yanai, K.3
Nagai, S.4
Wada, J.5
-
23
-
-
69949087531
-
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
-
doi:10.1371/journal.pone.0006816. PubMed: 19714243
-
Ji Q, Hao X, Zhang M, Tang W, Yang M et al. (2009) MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLOS ONE 4: e6816. doi:10.1371/journal.pone.0006816. PubMed: 19714243.
-
(2009)
PLOS ONE
, vol.4
-
-
Ji, Q.1
Hao, X.2
Zhang, M.3
Tang, W.4
Yang, M.5
-
24
-
-
70450225266
-
MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation
-
doi:10.1074/jbc.M109.046862. PubMed: 19723635
-
Song G, Zhang Y, Wang L (2009) MicroRNA-206 targets notch3, activates apoptosis, and inhibits tumor cell migration and focus formation. J Biol Chem 284: 31921-31927. doi:10.1074/jbc.M109.046862. PubMed: 19723635.
-
(2009)
J Biol Chem
, vol.284
, pp. 31921-31927
-
-
Song, G.1
Zhang, Y.2
Wang, L.3
-
25
-
-
79959842615
-
Modulation of microRNA expression in human T-cell development: Targeting of NOTCH3 by miR-150
-
doi:10.1182/blood-2010-12-326629. PubMed: 21551231
-
Ghisi M, Corradin A, Basso K, Frasson C, Serafin V et al. (2011) Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150. Blood 117: 7053-7062. doi:10.1182/blood-2010-12-326629. PubMed: 21551231.
-
(2011)
Blood
, vol.117
, pp. 7053-7062
-
-
Ghisi, M.1
Corradin, A.2
Basso, K.3
Frasson, C.4
Serafin, V.5
-
26
-
-
71549125896
-
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
-
doi: 10.1186/1471-2407-9-401. PubMed: 19922656
-
Sarver AL, French AJ, Borralho PM, Thayanithy V, Oberg AL et al. (2009) Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer 9: 401-416. doi: 10.1186/1471-2407-9-401. PubMed: 19922656.
-
(2009)
BMC Cancer
, vol.9
, pp. 401-416
-
-
Sarver, A.L.1
French, A.J.2
Borralho, P.M.3
Thayanithy, V.4
Oberg, A.L.5
-
27
-
-
84856510440
-
MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer
-
PubMed: 22179665
-
Migliore C, Martin V Leoni VP, Restivo A, Atzori L et al. (2012) MiR-1 downregulation cooperates with MACC1 in promoting MET overexpression in human colon cancer. Clin Cancer Res 18: 737-747. PubMed: 22179665.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 737-747
-
-
Migliore, C.1
Martin, V.2
Leoni, V.P.3
Restivo, A.4
Atzori, L.5
-
28
-
-
84859809988
-
miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation
-
PubMed: 22343615
-
Reid JF, Sokolova V, Zoni E, Lampis A, Pizzamiglio S et al. (2012) miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation. Mol Cancer Res 10: 504-515. PubMed: 22343615.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 504-515
-
-
Reid, J.F.1
Sokolova, V.2
Zoni, E.3
Lampis, A.4
Pizzamiglio, S.5
-
29
-
-
57749089758
-
Down-regulation of micro-RNA-1 (miR-1) in lung cancer
-
Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T et al. (2006) Down-regulation of micro-RNA-1 (miR-1) in lung cancer. J Boil Cancer 283: 33394-33405.
-
(2006)
J Boil Cancer
, vol.283
, pp. 33394-33405
-
-
Nasser, M.W.1
Datta, J.2
Nuovo, G.3
Kutay, H.4
Motiwala, T.5
-
30
-
-
79960856044
-
miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma
-
PubMed: 21378409
-
Nohata N, Sone Y, Hanazawa T, Fuse M, Kikkawa N et al. (2011) miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. Oncotarget 2: 29-42. PubMed: 21378409.
-
(2011)
Oncotarget
, vol.2
, pp. 29-42
-
-
Nohata, N.1
Sone, Y.2
Hanazawa, T.3
Fuse, M.4
Kikkawa, N.5
-
31
-
-
60549117358
-
Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy
-
doi:10.1158/0008-5472.CAN-08-2791. PubMed: 19208840
-
Indraccolo S, Minuzzo S, Masiero M, Pusceddu I, Persano L et al. (2009) Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy. Cancer Res 69: 1314-1323. doi:10.1158/0008-5472.CAN-08-2791. PubMed: 19208840.
-
(2009)
Cancer Res
, vol.69
, pp. 1314-1323
-
-
Indraccolo, S.1
Minuzzo, S.2
Masiero, M.3
Pusceddu, I.4
Persano, L.5
-
32
-
-
79959952635
-
Notch3 signalling promotes tumor growth in colorectal cancer
-
doi:10.1002/path.2895. PubMed: 21598247
-
Serafin V, Persano L, Moserle L, Esposito G, Ghisi M et al. (2011) Notch3 signalling promotes tumor growth in colorectal cancer. J Pathol 224: 448-460. doi:10.1002/path.2895. PubMed: 21598247.
-
(2011)
J Pathol
, vol.224
, pp. 448-460
-
-
Serafin, V.1
Persano, L.2
Moserle, L.3
Esposito, G.4
Ghisi, M.5
-
33
-
-
65549140672
-
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer
-
doi:10.1073/pnas.0813221106. PubMed: 19325125
-
Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V et al. (2009) Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci U-S-A 106: 6315-6320. doi:10.1073/pnas.0813221106. PubMed: 19325125.
-
(2009)
Proc Natl Acad Sci U-S-A
, vol.106
, pp. 6315-6320
-
-
Rodilla, V.1
Villanueva, A.2
Obrador-Hevia, A.3
Robert-Moreno, A.4
Fernández-Majada, V.5
-
34
-
-
84870023781
-
Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts
-
doi:10.1074/jbc.M112.378414. PubMed: 23055528
-
Gagan J, Dey BK, Layer R, Yan Z, Dutta A (2012) Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts. J Biol Chem 287: 40360-40370. doi:10.1074/jbc.M112. 378414. PubMed: 23055528.
-
(2012)
J Biol Chem
, vol.287
, pp. 40360-40370
-
-
Gagan, J.1
Dey, B.K.2
Layer, R.3
Yan, Z.4
Dutta, A.5
-
35
-
-
30044437240
-
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling
-
doi:10.1073/pnas.0509535102. PubMed: 16357195
-
Kwon C, Han Z, Olson EN, Srivastava D (2005) MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A 102: 18986-18991. doi:10.1073/pnas.0509535102. PubMed: 16357195.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18986-18991
-
-
Kwon, C.1
Han, Z.2
Olson, E.N.3
Srivastava, D.4
-
36
-
-
84874602762
-
miR-1-mediated induction of cardiogenesis in mesenchymal stem cells via downregulation of Hes-1
-
PubMed: 23509692
-
Huang F, Tang L, Fang ZF, Hu XQ, Pan JY et al. (2012) miR-1-mediated induction of cardiogenesis in mesenchymal stem cells via downregulation of Hes-1. Biomed Res Int. 2013: 216286. PubMed: 23509692.
-
(2012)
Biomed Res Int
, vol.2013
, pp. 216286
-
-
Huang, F.1
Tang, L.2
Fang, Z.F.3
Hu, X.Q.4
Pan, J.Y.5
-
37
-
-
80054773989
-
A systematic screen for micro-RNAs regulating the canonical Wnt pathway
-
doi:10.1371/journal.pone.0026257. PubMed: 22043311
-
Anton R, Chatterjee SS, Simundza J, Cowin P, Dasgupta R (2011) A systematic screen for micro-RNAs regulating the canonical Wnt pathway. PLOS ONE 6: e26257. doi:10.1371/journal.pone.0026257. PubMed: 22043311.
-
(2011)
PLOS ONE
, vol.6
-
-
Anton, R.1
Chatterjee, S.S.2
Simundza, J.3
Cowin, P.4
Dasgupta, R.5
-
38
-
-
78651446926
-
Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling
-
doi:10.1016/j.ccr.2010.11.008. PubMed: 21251616
-
Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H et al. (2011) Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling. Cancer Cell 19: 125-137. doi:10.1016/j.ccr.2010.11.008. PubMed: 21251616.
-
(2011)
Cancer Cell
, vol.19
, pp. 125-137
-
-
Sonoshita, M.1
Aoki, M.2
Fuwa, H.3
Aoki, K.4
Hosogi, H.5
|