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Volumn 10, Issue 12, 2009, Pages 1355-1362

The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in ApcMin/+mice

Author keywords

APC; Asef; Invasion; Metalloproteinase; Tumour

Indexed keywords

APC PROTEIN; GELATINASE B; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN ASEF; PROTEIN ASEF2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 73849118693     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2009.233     Document Type: Article
Times cited : (34)

References (17)
  • 1
    • 33845352555 scopus 로고    scopus 로고
    • Wnt signaling and the actin cytoskeleton
    • Akiyama T, Kawasaki Y (2006) Wnt signaling and the actin cytoskeleton. Oncogene 25: 7538-7544
    • (2006) Oncogene , vol.25 , pp. 7538-7544
    • Akiyama, T.1    Kawasaki, Y.2
  • 2
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B, Matrisian LM (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 296: 2387-2392
    • (2002) Science , vol.296 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 3
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 4
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2: 161-174
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 5
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N, Kerbel RS (2005) Angiogenesis as a therapeutic target. Nature 438: 967-974
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 6
    • 0035496104 scopus 로고    scopus 로고
    • APC, signal transduction and genetic instability in colorectal cancer
    • Fodde R, Smits R, Clevers H (2001) APC, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 1: 55-67
    • (2001) Nat Rev Cancer , vol.1 , pp. 55-67
    • Fodde, R.1    Smits, R.2    Clevers, H.3
  • 7
    • 4944239035 scopus 로고    scopus 로고
    • An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • Giraudo E, Inoue M, Hanahan D (2004) An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 114: 623-633
    • (2004) J Clin Invest , vol.114 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 8
    • 33846151992 scopus 로고    scopus 로고
    • Asef is a Cdc42-specific guanine nucleotide exchange factor
    • Gotthardt K, Ahmadian MR (2007) Asef is a Cdc42-specific guanine nucleotide exchange factor. Biol Chem 388: 67-71
    • (2007) Biol Chem , vol.388 , pp. 67-71
    • Gotthardt, K.1    Ahmadian, M.R.2
  • 9
    • 33846931753 scopus 로고    scopus 로고
    • Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element
    • Hamann MJ, Lubking CM, Luchini DN, Billadeau DD (2007) Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. Mol Cell Biol 27: 1380-1393
    • (2007) Mol Cell Biol , vol.27 , pp. 1380-1393
    • Hamann, M.J.1    Lubking, C.M.2    Luchini, D.N.3    Billadeau, D.D.4
  • 10
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298: 1911-1912
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 12
    • 0037341566 scopus 로고    scopus 로고
    • Mutated APC and Asef are involved in migration of colorectal tumour cells
    • Kawasaki Y, Sato R, Akiyama T (2003) Mutated APC and Asef are involved in migration of colorectal tumour cells. Nat Cell Biol 5: 211-215
    • (2003) Nat Cell Biol , vol.5 , pp. 211-215
    • Kawasaki, Y.1    Sato, R.2    Akiyama, T.3
  • 13
    • 36849095162 scopus 로고    scopus 로고
    • Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42
    • Kawasaki Y, Sagara M, Shibata S, Shirouzu M, Yokoyama S, Akiyama T (2007) Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. Oncogene 26: 7620-7627
    • (2007) Oncogene , vol.26 , pp. 7620-7627
    • Kawasaki, Y.1    Sagara, M.2    Shibata, S.3    Shirouzu, M.4    Yokoyama, S.5    Akiyama, T.6
  • 14
    • 31544441610 scopus 로고    scopus 로고
    • Distinct roles of macrophages in different tumor microenvironments
    • Lewis CE, Pollard JW (2006) Distinct roles of macrophages in different tumor microenvironments. Cancer Res 66: 605-612
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 15
    • 24644478136 scopus 로고    scopus 로고
    • Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development
    • Nateri AS, Spencer-Dene B, Behrens A (2005) Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development. Nature 437: 281-285
    • (2005) Nature , vol.437 , pp. 281-285
    • Nateri, A.S.1    Spencer-Dene, B.2    Behrens, A.3
  • 16
    • 55649090039 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse
    • Sinnamon MJ, Carter KJ, Fingleton B, Matrisian LM (2008) Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse. Int J Exp Pathol 89: 466-476
    • (2008) Int J Exp Pathol , vol.89 , pp. 466-476
    • Sinnamon, M.J.1    Carter, K.J.2    Fingleton, B.3    Matrisian, L.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.