Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways

Journal of Immunology

Volumn 192, Issue 2, 2014, Pages 630-640

  Williams, Joy A ^a   Zhang, Jingjing ^a   Jeon, Hyein ^a   Nitta, Takeshi ^b   Ohigashi, Izumi ^b   Klug, David ^a   Kruhlak, Michael J ^a   Choudhury, Baishakhi ^a   Sharrow, Susan O ^a   Granger, Larry ^a   Adams, Anthony ^a   Eckhaus, Michael A ^a   Jenkinson, S Rhiannon ^a   Richie, Ellen R ^c   Gress, Ronald E ^a   Takahama, Yousuke ^b   Hodes, Richard J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD86 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOTOXIN; LYMPHOTOXIN BETA; T LYMPHOCYTE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; MEDULLARY THYMIC EPITHELIAL CELL; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD40; ANTIGENS, CD80; ANTIGENS, CD86; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; EPITHELIAL CELLS; EPITHELIUM; KILLER CELLS, NATURAL; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NF-KAPPA B; RECEPTORS, ANTIGEN, T-CELL; SELF TOLERANCE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; THYMOCYTES; UP-REGULATION;

EID: 84892741006     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302550     Document Type: Article

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