Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart

PLoS Genetics

Volumn 9, Issue 12, 2013, Pages

  Melkani, Girish C ^a,b   Trujillo, Adriana S ^a   Ramos, Raul ^a   Bodmer, Rolf ^b   Bernstein, Sanford I ^a   Ocorr, Karen ^b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; POLYGLUTAMINE; SUPEROXIDE DISMUTASE; UNC 45 PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DROSOPHILA; FEMALE; HEART AMYLOIDOSIS; HEART ARRHYTHMIA; HEART DILATATION; HEART FAILURE; HEART MUSCLE CELL; HUNTINGTON CHOREA; MALE; MOLECULAR PATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN UNFOLDING; SIGNAL TRANSDUCTION;

AMYLOID; AMYLOIDOSIS; ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HEART; HUMANS; HUNTINGTON DISEASE; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; OXIDATIVE STRESS; PEPTIDES; PROTEIN FOLDING; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 84892738799     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004024     Document Type: Article

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