cAMP–PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3–Orai1 complex

Pflugers Archiv European Journal of Physiology

Volumn 466, Issue 10, 2014, Pages 1921-1932

  Clarysse, Lucie ^a,b   Guéguinou, Maxime ^a,b   Potier Cartereau, Marie ^a,b   Vandecasteele, Grégoire ^c,d   Bougnoux, Philippe ^a,b,e   Chevalier, Stephan ^a,b   Chantôme, Aurélie ^a,b   Vandier, Christophe ^a,b  

^a CHRU de Tours   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c INSERM   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e UNIVERSITY HOSPITAL OF TOURS   (France)

Author keywords

Breast cancer; Calcium entry; cAMP; Migration; PKA; SK3 channel

Indexed keywords

AZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM; CALCIUM CHANNEL; CARBAZOLE DERIVATIVE; CI 1044; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; ISOPRENALINE; KCNN3 PROTEIN, HUMAN; KT 5720; NICOTINAMIDE; ORAI1 PROTEIN, HUMAN; PHOSPHODIESTERASE IV INHIBITOR; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; PYRROLE DERIVATIVE; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL MEMBRANE; CELL MOTION; HEK293 CELL LINE; HUMAN; METABOLISM; TUMOR CELL LINE;

ADRENERGIC BETA-AGONISTS; AZEPINES; CALCIUM; CALCIUM CHANNELS; CARBAZOLES; CELL LINE, TUMOR; CELL MOVEMENT; COLFORSIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEK293 CELLS; HUMANS; ISOPROTERENOL; MEMBRANE MICRODOMAINS; NIACINAMIDE; PHOSPHODIESTERASE 4 INHIBITORS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PYRROLES; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 84892719144     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-013-1435-5     Document Type: Article

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