Targeting SKCa channels in cancer: Potential new therapeutic approaches

Current Medicinal Chemistry

Volumn 19, Issue 5, 2012, Pages 697-713

  Girault, A ^a,b   Haelters, J P ^c   Potier Cartereau, M ^a,b   Chantome A ^a,b   Jaffres P A ^c   Bougnoux, P ^a,b,d   Joulin, V ^a   Vandier, C ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

^d CHU BRETONNEAU   (France)

Author keywords

Amphiphiles; BKCa channel; Breast cancer; Colon cancer; Edelfosine; IKCa channel; Melanoma; SK1; SK2; SK3; SKCa activators; SKCa channel; SKCa inhibitors

Indexed keywords

AMPHOPHILE; ANTINEOPLASTIC AGENT; CALMODULIN BINDING PROTEIN; EDELFOSINE; OHMLINE; SK2 CHANNEL; SK3 CHANNEL; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

BREAST CANCER; CALCIUM CELL LEVEL; CANCER THERAPY; CELL MIGRATION; CELL PROLIFERATION; COLON CANCER; DRUG BINDING SITE; DRUG TARGETING; ELECTROPHYSIOLOGY; HUMAN; MELANOMA; NONHUMAN; POTASSIUM CONDUCTANCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; TUMOR CELL;

ANTINEOPLASTIC AGENTS; APAMIN; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASMS; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPID ETHERS; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS;

EID: 84857731900     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712798992039     Document Type: Review

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