Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice

Gastroenterology

Volumn 146, Issue 2, 2014, Pages

  McClain, Jonathon L ^a   Grubišić, Vladimir ^b   Fried, David ^c   Gomez Suarez, Roberto A ^b,d   Leinninger, Gina M ^a   Sévigny, Jean ^e,f   Parpura, Vladimir ^b,g   Gulbransen, Brian D ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b University of Alabama at Birmingham   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d NEMOURS CHILDREN S HOSPITAL   (United States)

^e UNIVERSITÉ LAVAL   (Canada)

^f LAVAL UNIVERSITY   (Canada)

^g University of Rijeka   (Croatia)

Author keywords

Aging; Intestinal Nervous System; Mouse Model; Purines

Indexed keywords

CALCIUM; CARBENOXOLONE; CONNEXIN 43; MESSENGER RNA; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; CALCIUM CHANNEL; GJA1 PROTEIN, MOUSE; GLIAL FIBRILLARY ACIDIC PROTEIN; PURINE DERIVATIVE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; COLONIC TRANSIT; CONTROLLED STUDY; ENTERIC GLIA; FEMALE; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRANSIT; GENE DISRUPTION; GLIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; MUSCLE TONE; MYENTERIC PLEXUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; CA(2+); CALCIUM SIGNALING; CBX; COLON; CONNEXIN-43; CX43; DRUG ANTAGONISM; EG; ENS; ER(T2); GENETICS; GFAP; I-CKO; INDUCIBLE AND CONDITIONAL KNOCKOUT; INTESTINAL NERVOUS SYSTEM; INTESTINE INNERVATION; KNOCKOUT MOUSE; METABOLISM; MOA; MONTHS OF AGE; MOUSE MODEL; MUTATED ESTROGEN RECEPTOR; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADP; AGING; ATP; CA(2+); CALCIUM; CARBENOXOLONE; CBX; CONNEXIN-43; CX43; EG; ENS; ENTERIC GLIA; ENTERIC NERVOUS SYSTEM; ER(T2); GFAP; GLIAL FIBRILLARY ACIDIC PROTEIN; I-CKO; INDUCIBLE AND CONDITIONAL KNOCKOUT; INTESTINAL NERVOUS SYSTEM; MESSENGER RNA; MOA; MONTHS OF AGE; MOUSE MODEL; MRNA; MUTATED ESTROGEN RECEPTOR; PURINES;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CALCIUM CHANNELS; CALCIUM SIGNALING; COLON; CONNEXIN 43; ENTERIC NERVOUS SYSTEM; FEMALE; GASTROINTESTINAL TRANSIT; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROGLIA; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84892690902     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.10.061     Document Type: Article

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