Aminoalkyl methacrylate copolymers for improving the solubility of tacrolimus. I: Evaluation of solid dispersion formulations

International Journal of Pharmaceutics

Volumn 428, Issue 1-2, 2012, Pages 18-24

  Yoshida, Takatsune ^a,b   Kurimoto, Ippei ^a   Yoshihara, Keiichi ^a   Umejima, Hiroyuki ^a   Ito, Naoki ^a   Watanabe, Shunsuke ^a   Sako, Kazuhiro ^a   Kikuchi, Akihiko ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Eudragit E; Reprecipitation inhibitor; Solid dispersion; Solubilization; Supersaturation; Tacrolimus

Indexed keywords

ALCOHOL; DRUG CARRIER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE; TACROLIMUS;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG SOLUBILITY; PARTICLE SIZE; POWDER; PRECIPITATION; PRIORITY JOURNAL; SOLID DISPERSION FORMULATION; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; METHYLCELLULOSE; METHYLMETHACRYLATES; SOLUBILITY; TACROLIMUS; WATER;

EID: 84859432573     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.041     Document Type: Article

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