A novel surface-attached carvedilol solid dispersion with enhanced solubility and dissolution

Archives of Pharmacal Research

Volumn 36, Issue 1, 2013, Pages 79-85

  Lee, Sung Neung ^a   Poudel, Bijay Kumar ^a   Tran, Tuan Hiep ^a   Marasini, Nirmal ^a   Pradhan, Roshan ^a   Lee, Young Im ^a   Lee, Dong Won ^a   Woo, Jong Soo ^a   Choi, Han Gon ^b   Yong, Chul Soon ^a   Kim, Jong Oh ^a  

^a Yeungnam University   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Bioavailability; Carrier; Carvedilol; Solid dispersion; Solubility

Indexed keywords

CARVEDILOL; POLYSORBATE 80; POVIDONE; SURFACTANT;

AQUEOUS SOLUTION; ARTICLE; BIOAVAILABILITY; CRYSTAL; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; HYDROPHILICITY; HYDROPHOBICITY; MELTING POINT; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; SOLID DISPERSION; SPRAY DRYING; X RAY DIFFRACTION;

ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS; CALORIMETRY, DIFFERENTIAL SCANNING; CARBAZOLES; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLIZATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROSCOPY, ELECTRON, SCANNING; POVIDONE; PROPANOLAMINES; SOLUBILITY; SOLVENTS; SURFACE PROPERTIES; X-RAY DIFFRACTION;

EID: 84873735800     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0008-7     Document Type: Article

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