Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)

Journal of Biological Chemistry

Volumn 289, Issue 3, 2014, Pages 1798-1814

  Yates, Christopher J ^a   Masuyer, Geoffrey ^b   Schwager, Sylva L U ^a   Akif, Mohd ^b,c   Sturrock, Edward D ^a   Acharya, K Ravi ^b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b University of Bath   (United Kingdom)

^c UNIVERSITY OF HYDERABAD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN-CONVERTING ENZYME; CHLORIDE CONCENTRATIONS; ISOTHERMAL TITRATION CALORIMETRY; SUBSTRATE COMPOSITION; SUBSTRATE INTERACTION; SUBSTRATE SPECIFICITY; THERMODYNAMIC MECHANISM; X RAY CRYSTAL STRUCTURES;

BLOOD PRESSURE; ENZYMES; PHYSIOLOGY; SUBSTRATES;

CHLORINE COMPOUNDS;

ARGININE; DIPEPTIDYL CARBOXYPEPTIDASE; GLUTAMIC ACID; LYSINE; ACE PROTEIN, HUMAN; CHLORIDE; PROTEIN BINDING;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HUMAN; HUMAN CELL; HYDROLYSIS; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; THERMODYNAMICS; BINDING SITE; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; BINDING SITES; CHLORIDES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MUTATION, MISSENSE; PEPTIDYL-DIPEPTIDASE A; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84892628652     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.512335     Document Type: Article

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