Angiotensin I-converting Enzyme Transition State Stabilization by His 1089: Evidence for a catalytic mechanism distinct from other gluzincin metalloproteinases

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 4998-5004

  Fernandez, Marian ^a   Liu, Xifu ^a   Wouters, Merridee A ^a   Heyberger, Sophie ^a   Husain, Ahsan ^a,b  

^a VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; DEGRADATION; ENZYMES; HYDROGEN BONDS; MUTAGENESIS; PH EFFECTS; ZINC;

METALLOPROTEINASES; TRANSITION STATE BINDING;

BIOCHEMISTRY;

ALANINE; ANGIOTENSIN; ANGIOTENSIN I; BRADYKININ; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; GLUZINCIN; HISTIDINE; LEUCINE; METALLOPROTEINASE; PEPTIDASE; THERMOLYSIN; UNCLASSIFIED DRUG; ASPARAGINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LISINOPRIL; RECOMBINANT PROTEIN;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STABILITY; HYDROGEN BOND; PH; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL STRAIN COS1; CHEMISTRY; COMPARATIVE STUDY; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

FELIS CATUS;

AMINO ACID SEQUENCE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ASPARAGINE; BINDING SITES; CAPTOPRIL; CATALYSIS; COS CELLS; HISTIDINE; HUMANS; LISINOPRIL; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PEPTIDYL-DIPEPTIDASE A; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION;

EID: 0035895889     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009009200     Document Type: Article

References (34)

1. Corvol, P., and Williams T. A. (1998) in Handbook of Proteolytic Enzymes (Barrett, A. J., Rawlings, N. D., and Woessner, J. F., eds) pp. 1066-1076, Academic Press, New York
2. Soubrier, F., Alhenc-Gelas, F., Hubert, C., Allegrini, J., John, M., Tregear, G., and Corvol, P. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 9386-9390
3. Lamango, N. S., Sajid, M., and Isaac, R. E. (1996) Biochem. J. 314, 639-646
4. Burrell, L. M., and Johnston, C. I. (2000) in Drugs, Enzymes, and Receptors of the Renin-Angiotensin System: Celebrating a Century of Discovery (Husain, A., and Graham, R. M., eds) pp. 191-200, Harwood Academic Publishers, The Netherlands
5. Barrett, A. J., Rawlings, N. D., and Woessner, J. F. (1998) Handbook of Proteolytic Enzymes, pp. 992-993, Academic Press, New York
6. Matthews, B. W. (1988) Acc. Chem. Res. 21, 333-340
7. Hangauer, D. G., Monzingo, A. F., and Matthews B. W. (1984) Biochemistry 23, 5730-5741
8. Williams, T. A., Corvol, P., and Soubrier, F. (1994) J. Biol. Chem. 269, 29430-29434
9. Chandrasekharan, U. M., Sanker, S., Glynias, M. J., Karnik, S. S., and Husain, A. (1996) Science 271, 502-505
10. Sanker, S., Chandrasekharan, U. M., Wilk, D., Glynias, M. J., Karnik, S. S., and Husain, A. (1997) J. Biol. Chem. 272, 2963-2968
11. Wells, J. A. (1990) Biochemistry 29, 8509-8517
12. Beaumont, A., O'Donohue, M. J., Paredes, N., Rousselet, N., Assicot, M., Bohuon, C., Fournie-Zaluski, M.-C., and Roques, B. P. (1995) J. Biol. Chem. 270, 16803-16808
13. Dion, N., LeMoual, H., Crine, P., and Boileau, G. (1993) FEBS Lett. 318, 301-304
14. Holden, H. M., and Matthews, B. W. (1988) J. Biol. Chem. 263, 3256-3260
15. Oefner, C., D'Arcy, A., Hennig, M., Winkler, F. K., and Dale, G. E. (2000) J. Mol. Biol. 296, 341-349
16. Wei, L., Ahlenc-Gelas, F., Corvol, P., and Clauser, E. (1991) J. Biol. Chem. 266, 9002-9008
17. Jaspard, E., Wei, L., and Alhenc-Gelas, F. (1993) J. Biol. Chem. 268, 9496-9503
18. Fersht, A. R. (1999) Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding, pp. 169-173, W. H. Freeman & Co., New York
19. Roderick, S. L., Fournie-Zaluski, M. C., Roques, B. P., and Matthews, B. W. (1989) Biochemistry 28, 1493-1497
20. Monzingo, A. F., and Matthews, B. W. (1982) Biochemistry 21, 3390-3394
21. Holmes, M. A., and Matthews, B. W. (1981) Biochemistry 20, 6912-6920
22. Hausrath, A. C., and Matthews, B. W. (1994) J. Biol. Chem. 269, 18839-18842
23. Monzingo, A. F., and Matthews, B. W. (1984) Biochemistry 23, 5724-5729
24. Tronrud, D. E., Monzingo, A. F., and Matthews, B. W. (1986) Eur. J. Biochem. 157, 261-268
25. Allen, F. H., Bird, C. M., Rowland, R. S., and Raithby, P. R. (1997) Acta Crystallogr. Sect. B Struct. Sci. 53, 680-695
26. Allen, F. H., Bird, C. M., Rowland, R. S., and Raithby, P. R. (1997) Acta Crystallogr. Sect. B Struct. Sci. 53, 696-701
27. Desiraju, G. R., and Steiner, T. (1999) The Weak Hydrogen Bond in Structural Chemistry and Biology, pp. 11-15, Oxford University Press, New York
28. Power, L. F., Turner, K. E., and Moore, F. H. (1976) J. Chem. Soc. Perkin Trans. II 249-252
29. Robl, J. A., Trippodo, N. C., and Petrillo, E. W. (1997) in Antihypertensive Drugs (Zwieten, P. A. V., and Greenlee, W. J., eds) pp. 118-119, Harwood Academic Publishers, The Netherlands
30. Kester, W. R., and Matthews, B. W. (1977) Biochemistry 16, 2506-2516
31. Colman, P. M., Jansonius, J. N., and Matthews, B. W. (1972) J. Mol. Biol. 70, 701-724
32. Bunning, P., and Riordan, J. F. (1981) Isr. J. Chem. 21, 43-47
33. Shapiro, P., Holmquist, B., and Riordan, J. F. (1983) Biochemistry 22, 3850-3857
34. Schechter, I., and Berger, A. (1967) Biochem. Biophys. Res. Commun. 27, 157-162