Kindlin-2 regulates renal tubular cell plasticity by activation of Ras and its downstream signaling

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 2, 2014, Pages

  Wei, Xiaofan ^a,b   Wang, Xiang ^a,b   Xia, Yang ^a,b   Tang, Yan ^a,b   Li, Feng ^a,b   Fang, Weigang ^a,b   Zhang, Hongquan ^a,b  

^a Amsterdam   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Kindlin 2; Ras signaling; Tubular cell plasticity

Indexed keywords

ADAPTOR PROTEIN; ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN KINDLIN 2; RAS PROTEIN; SOS PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

KINDLIN-2; RAS SIGNALING; TUBULAR CELL PLASTICITY;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOSKELETAL PROTEINS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FLUORESCENT ANTIBODY TECHNIQUE; GENES, RAS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KIDNEY TUBULES; MAP KINASE SIGNALING SYSTEM; MICE; MUSCLE PROTEINS; NEPHRITIS, INTERSTITIAL; ONCOGENE PROTEIN V-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOS1 PROTEIN; TRANSFECTION; URETERAL OBSTRUCTION;

EID: 84892618239     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00499.2013     Document Type: Article

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