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Volumn 14, Issue 1, 2014, Pages

MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells

Author keywords

Gastric cancer; Metastasis; MicroRNA; miR 133b

Indexed keywords

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; STOMACH NEOPLASMS;

EID: 84892609584     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-34     Document Type: Article
Times cited : (33)

References (53)
  • 2
    • 38549182603 scopus 로고    scopus 로고
    • The role of microRNAs in cancer
    • 1994807, 17940623
    • Stahlhut Espinosa CE, Slack FJ. The role of microRNAs in cancer. Yale J Biol Med 2006, 79(3-4):131-140. 1994807, 17940623.
    • (2006) Yale J Biol Med , vol.79 , Issue.3-4 , pp. 131-140
    • Stahlhut Espinosa, C.E.1    Slack, F.J.2
  • 3
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Canc 2006, 6(4):259-269.
    • (2006) Nat Rev Canc , vol.6 , Issue.4 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 4
    • 53949090314 scopus 로고    scopus 로고
    • Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
    • 10.1186/1471-2407-8-266, 2564978, 18803879
    • Ji Q, Hao XB, Meng Y, Zhang M, DeSano J, Fan DM, Xu L. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 2008, 8:266. 10.1186/1471-2407-8-266, 2564978, 18803879.
    • (2008) BMC Cancer , vol.8 , pp. 266
    • Ji, Q.1    Hao, X.B.2    Meng, Y.3    Zhang, M.4    DeSano, J.5    Fan, D.M.6    Xu, L.7
  • 5
    • 77955429106 scopus 로고    scopus 로고
    • MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
    • 10.1186/1471-2407-10-367, 2914702, 20618998
    • Zhang CZ, Han L, Zhang AL, Fu YC, Yue XA, Wang GX, Jia ZF, Pu PY, Zhang QY, Kang CS. MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN. BMC Cancer 2010, 10:367. 10.1186/1471-2407-10-367, 2914702, 20618998.
    • (2010) BMC Cancer , vol.10 , pp. 367
    • Zhang, C.Z.1    Han, L.2    Zhang, A.L.3    Fu, Y.C.4    Yue, X.A.5    Wang, G.X.6    Jia, Z.F.7    Pu, P.Y.8    Zhang, Q.Y.9    Kang, C.S.10
  • 7
    • 77956915352 scopus 로고    scopus 로고
    • MiR-126 functions as a tumour suppressor in human gastric cancer
    • 10.1016/j.canlet.2010.06.004, 20619534
    • Feng R, Chen X, Yu Y, Su L, Yu B, Li J, Cai Q, Yan M, Liu B, Zhu Z. miR-126 functions as a tumour suppressor in human gastric cancer. Cancer Lett 2010, 298(1):50-63. 10.1016/j.canlet.2010.06.004, 20619534.
    • (2010) Cancer Lett , vol.298 , Issue.1 , pp. 50-63
    • Feng, R.1    Chen, X.2    Yu, Y.3    Su, L.4    Yu, B.5    Li, J.6    Cai, Q.7    Yan, M.8    Liu, B.9    Zhu, Z.10
  • 8
    • 84862787132 scopus 로고    scopus 로고
    • MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer
    • 10.1016/j.canlet.2012.02.030, 22388101
    • Li C, Nie H, Wang M, Su L, Li J, Yu B, Wei M, Ju J, Yu Y, Yan M, et al. MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. Cancer Lett 2012, 320(2):189-197. 10.1016/j.canlet.2012.02.030, 22388101.
    • (2012) Cancer Lett , vol.320 , Issue.2 , pp. 189-197
    • Li, C.1    Nie, H.2    Wang, M.3    Su, L.4    Li, J.5    Yu, B.6    Wei, M.7    Ju, J.8    Yu, Y.9    Yan, M.10
  • 9
    • 84864287425 scopus 로고    scopus 로고
    • Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK
    • 10.1016/j.febslet.2012.05.050, 22677169
    • Wang M, Li C, Nie H, Lv X, Qu Y, Yu B, Su L, Li J, Chen X, Ju J, et al. Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK. FEBS Lett 2012, 586(16):2382-2388. 10.1016/j.febslet.2012.05.050, 22677169.
    • (2012) FEBS Lett , vol.586 , Issue.16 , pp. 2382-2388
    • Wang, M.1    Li, C.2    Nie, H.3    Lv, X.4    Qu, Y.5    Yu, B.6    Su, L.7    Li, J.8    Chen, X.9    Ju, J.10
  • 10
    • 84863011293 scopus 로고    scopus 로고
    • MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
    • 3583594, 22267008
    • Zhang BG, Li JF, Yu BQ, Zhu ZG, Liu BY, Yan M. microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. Oncol Rep 2012, 27(4):1019-1026. 3583594, 22267008.
    • (2012) Oncol Rep , vol.27 , Issue.4 , pp. 1019-1026
    • Zhang, B.G.1    Li, J.F.2    Yu, B.Q.3    Zhu, Z.G.4    Liu, B.Y.5    Yan, M.6
  • 11
    • 84877348831 scopus 로고    scopus 로고
    • Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer
    • 10.1007/s00535-012-0733-6, 23338485
    • Wang M, Li C, Yu B, Su L, Li J, Ju J, Yu Y, Gu Q, Zhu Z, Liu B. Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer. J Gastroenterol 2013, 48(9):1023-1033. 10.1007/s00535-012-0733-6, 23338485.
    • (2013) J Gastroenterol , vol.48 , Issue.9 , pp. 1023-1033
    • Wang, M.1    Li, C.2    Yu, B.3    Su, L.4    Li, J.5    Ju, J.6    Yu, Y.7    Gu, Q.8    Zhu, Z.9    Liu, B.10
  • 13
    • 63849206509 scopus 로고    scopus 로고
    • Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues
    • 10.1111/j.1440-1746.2008.05666.x, 19175831
    • Guo J, Miao Y, Xiao B, Huan R, Jiang Z, Meng D, Wang Y. Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol 2009, 24(4):652-657. 10.1111/j.1440-1746.2008.05666.x, 19175831.
    • (2009) J Gastroenterol Hepatol , vol.24 , Issue.4 , pp. 652-657
    • Guo, J.1    Miao, Y.2    Xiao, B.3    Huan, R.4    Jiang, Z.5    Meng, D.6    Wang, Y.7
  • 14
    • 31744432337 scopus 로고    scopus 로고
    • The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
    • 10.1038/ng1725, 2538576, 16380711
    • Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006, 38(2):228-233. 10.1038/ng1725, 2538576, 16380711.
    • (2006) Nat Genet , vol.38 , Issue.2 , pp. 228-233
    • Chen, J.F.1    Mandel, E.M.2    Thomson, J.M.3    Wu, Q.4    Callis, T.E.5    Hammond, S.M.6    Conlon, F.L.7    Wang, D.Z.8
  • 15
    • 33747628074 scopus 로고    scopus 로고
    • Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
    • 1550420, 16854228
    • Bandres E, Cubedo E, Agirre X, Malumbres R, Zarate R, Ramirez N, Abajo A, Navarro A, Moreno I, Monzo M, et al. Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 2006, 5:29. 1550420, 16854228.
    • (2006) Mol Cancer , vol.5 , pp. 29
    • Bandres, E.1    Cubedo, E.2    Agirre, X.3    Malumbres, R.4    Zarate, R.5    Ramirez, N.6    Abajo, A.7    Navarro, A.8    Moreno, I.9    Monzo, M.10
  • 16
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue
    • 10.1158/1078-0432.CCR-07-0666, 18451220
    • Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008, 14(9):2588-2592. 10.1158/1078-0432.CCR-07-0666, 18451220.
    • (2008) Clin Cancer Res , vol.14 , Issue.9 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3    Ng, R.W.4    Yuen, A.P.5    Wei, W.I.6
  • 17
  • 20
    • 77956181723 scopus 로고    scopus 로고
    • MiR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
    • 10.1002/ijc.25284, 21351259
    • Kano M, Seki N, Kikkawa N, Fujimura L, Hoshino I, Akutsu Y, Chiyomaru T, Enokida H, Nakagawa M, Matsubara H. miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int J Cancer 2010, 127(12):2804-2814. 10.1002/ijc.25284, 21351259.
    • (2010) Int J Cancer , vol.127 , Issue.12 , pp. 2804-2814
    • Kano, M.1    Seki, N.2    Kikkawa, N.3    Fujimura, L.4    Hoshino, I.5    Akutsu, Y.6    Chiyomaru, T.7    Enokida, H.8    Nakagawa, M.9    Matsubara, H.10
  • 21
    • 84866124741 scopus 로고    scopus 로고
    • MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways
    • 10.1038/onc.2011.561, 22179829
    • Qin W, Dong P, Ma C, Mitchelson K, Deng T, Zhang L, Sun Y, Feng X, Ding Y, Lu X, et al. MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways. Oncogene 2012, 31(36):4067-4075. 10.1038/onc.2011.561, 22179829.
    • (2012) Oncogene , vol.31 , Issue.36 , pp. 4067-4075
    • Qin, W.1    Dong, P.2    Ma, C.3    Mitchelson, K.4    Deng, T.5    Zhang, L.6    Sun, Y.7    Feng, X.8    Ding, Y.9    Lu, X.10
  • 22
    • 84860011976 scopus 로고    scopus 로고
    • MicroRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers
    • 3292888, 22308266
    • Nohata N, Hanazawa T, Enokida H, Seki N. microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget 2012, 3(1):9-21. 3292888, 22308266.
    • (2012) Oncotarget , vol.3 , Issue.1 , pp. 9-21
    • Nohata, N.1    Hanazawa, T.2    Enokida, H.3    Seki, N.4
  • 23
    • 20144387999 scopus 로고    scopus 로고
    • Accurate discrimination of Barrett's esophagus and esophageal adenocarcinoma using a quantitative three-tiered algorithm and multimarker real-time reverse transcription-PCR
    • 10.1158/1078-0432.CCR-04-1091, 15788668
    • Mitas M, Almeida JS, Mikhitarian K, Gillanders WE, Lewin DN, Spyropoulos DD, Hoover L, Graham A, Glenn T, King P, et al. Accurate discrimination of Barrett's esophagus and esophageal adenocarcinoma using a quantitative three-tiered algorithm and multimarker real-time reverse transcription-PCR. Clin Cancer Res 2005, 11(6):2205-2214. 10.1158/1078-0432.CCR-04-1091, 15788668.
    • (2005) Clin Cancer Res , vol.11 , Issue.6 , pp. 2205-2214
    • Mitas, M.1    Almeida, J.S.2    Mikhitarian, K.3    Gillanders, W.E.4    Lewin, D.N.5    Spyropoulos, D.D.6    Hoover, L.7    Graham, A.8    Glenn, T.9    King, P.10
  • 24
    • 33947254565 scopus 로고    scopus 로고
    • Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells
    • 10.1158/0008-5472.CAN-06-3625, 17332338
    • Lee JL, Wang MJ, Sudhir PR, Chen GD, Chi CW, Chen JY. Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells. Cancer Res 2007, 67(5):2089-2097. 10.1158/0008-5472.CAN-06-3625, 17332338.
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 2089-2097
    • Lee, J.L.1    Wang, M.J.2    Sudhir, P.R.3    Chen, G.D.4    Chi, C.W.5    Chen, J.Y.6
  • 27
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • 10.1016/S0092-8674(03)01018-3, 14697198
    • Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003, 115(7):787-798. 10.1016/S0092-8674(03)01018-3, 14697198.
    • (2003) Cell , vol.115 , Issue.7 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3    Bartel, D.P.4    Burge, C.B.5
  • 28
    • 33747849920 scopus 로고    scopus 로고
    • RNAhybrid: microRNA target prediction easy, fast and flexible
    • 1538877, 16845047
    • Kruger J, Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res 2006, 34(Web Server issue):W451-W454. 1538877, 16845047.
    • (2006) Nucleic Acids Res , vol.34 , Issue.WEB SERVER ISSUE
    • Kruger, J.1    Rehmsmeier, M.2
  • 30
    • 81155126047 scopus 로고    scopus 로고
    • Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer
    • 10.1158/0008-5472.CAN-11-1338, 21975935
    • Yoo YA, Kang MH, Lee HJ, Kim BH, Park JK, Kim HK, Kim JS, Oh SC. Sonic hedgehog pathway promotes metastasis and lymphangiogenesis via activation of Akt, EMT, and MMP-9 pathway in gastric cancer. Cancer Res 2011, 71(22):7061-7070. 10.1158/0008-5472.CAN-11-1338, 21975935.
    • (2011) Cancer Res , vol.71 , Issue.22 , pp. 7061-7070
    • Yoo, Y.A.1    Kang, M.H.2    Lee, H.J.3    Kim, B.H.4    Park, J.K.5    Kim, H.K.6    Kim, J.S.7    Oh, S.C.8
  • 31
    • 58749087502 scopus 로고    scopus 로고
    • Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers
    • 2634717, 19107131
    • Ohta H, Aoyagi K, Fukaya M, Danjoh I, Ohta A, Isohata N, Saeki N, Taniguchi H, Sakamoto H, Shimoda T. Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers. Br J Cancer 2008, 100(2):389-398. 2634717, 19107131.
    • (2008) Br J Cancer , vol.100 , Issue.2 , pp. 389-398
    • Ohta, H.1    Aoyagi, K.2    Fukaya, M.3    Danjoh, I.4    Ohta, A.5    Isohata, N.6    Saeki, N.7    Taniguchi, H.8    Sakamoto, H.9    Shimoda, T.10
  • 32
    • 84863609332 scopus 로고    scopus 로고
    • ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells
    • 10.1007/s10620-012-2042-6, 22350782
    • Dai YH, Tang YP, Zhu HY, Lv L, Chu Y, Zhou YQ, Huo JR. ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells. Dig Dis Sci 2012, 57(5):1253-1260. 10.1007/s10620-012-2042-6, 22350782.
    • (2012) Dig Dis Sci , vol.57 , Issue.5 , pp. 1253-1260
    • Dai, Y.H.1    Tang, Y.P.2    Zhu, H.Y.3    Lv, L.4    Chu, Y.5    Zhou, Y.Q.6    Huo, J.R.7
  • 34
    • 84872195355 scopus 로고    scopus 로고
    • Osteopontin splice variants differentially exert clinicopathological features and biological functions in gastric cancer
    • 3535534, 23289017
    • Tang X, Li J, Yu B, Su L, Yu Y, Yan M, Liu B, Zhu Z. Osteopontin splice variants differentially exert clinicopathological features and biological functions in gastric cancer. Int J Biol Sci 2013, 9(1):55-66. 3535534, 23289017.
    • (2013) Int J Biol Sci , vol.9 , Issue.1 , pp. 55-66
    • Tang, X.1    Li, J.2    Yu, B.3    Su, L.4    Yu, Y.5    Yan, M.6    Liu, B.7    Zhu, Z.8
  • 35
    • 67650070517 scopus 로고    scopus 로고
    • Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus
    • 10.1002/ijc.24400, 19431210
    • Isohata N, Aoyagi K, Mabuchi T, Daiko H, Fukaya M, Ohta H, Ogawa K, Yoshida T, Sasaki H. Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus. Int J Cancer 2009, 125(5):1212-1221. 10.1002/ijc.24400, 19431210.
    • (2009) Int J Cancer , vol.125 , Issue.5 , pp. 1212-1221
    • Isohata, N.1    Aoyagi, K.2    Mabuchi, T.3    Daiko, H.4    Fukaya, M.5    Ohta, H.6    Ogawa, K.7    Yoshida, T.8    Sasaki, H.9
  • 36
    • 69249200489 scopus 로고    scopus 로고
    • The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin
    • 10.1074/jbc.M109.021949, 2755696, 19556240
    • Das S, Harris LG, Metge BJ, Liu S, Riker AI, Samant RS, Shevde LA. The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin. J Biol Chem 2009, 284(34):22888-22897. 10.1074/jbc.M109.021949, 2755696, 19556240.
    • (2009) J Biol Chem , vol.284 , Issue.34 , pp. 22888-22897
    • Das, S.1    Harris, L.G.2    Metge, B.J.3    Liu, S.4    Riker, A.I.5    Samant, R.S.6    Shevde, L.A.7
  • 37
    • 0037423845 scopus 로고    scopus 로고
    • Vertebrate microRNA genes
    • 10.1126/science.1080372, 12624257
    • Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP. Vertebrate microRNA genes. Science 2003, 299(5612):1540-1540. 10.1126/science.1080372, 12624257.
    • (2003) Science , vol.299 , Issue.5612 , pp. 1540-1540
    • Lim, L.P.1    Glasner, M.E.2    Yekta, S.3    Burge, C.B.4    Bartel, D.P.5
  • 38
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • 10.1016/j.cell.2007.04.040, 2681231, 17604727
    • Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007, 129(7):1401-1414. 10.1016/j.cell.2007.04.040, 2681231, 17604727.
    • (2007) Cell , vol.129 , Issue.7 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3    Sewer, A.4    Iovino, N.5    Aravin, A.6    Pfeffer, S.7    Rice, A.8    Kamphorst, A.O.9    Landthaler, M.10
  • 39
    • 80053063873 scopus 로고    scopus 로고
    • Potentially predictive microRNAs of gastric cancer with metastasis to lymph node
    • 10.3748/wjg.v17.i31.3645, 3180023, 21987613
    • Wu WY, Xue XY, Chen ZJ, Han SL, Huang YP, Zhang LF, Zhu GB, Shen X. Potentially predictive microRNAs of gastric cancer with metastasis to lymph node. World J Gastroenterol 2011, 17(31):3645-3651. 10.3748/wjg.v17.i31.3645, 3180023, 21987613.
    • (2011) World J Gastroenterol , vol.17 , Issue.31 , pp. 3645-3651
    • Wu, W.Y.1    Xue, X.Y.2    Chen, Z.J.3    Han, S.L.4    Huang, Y.P.5    Zhang, L.F.6    Zhu, G.B.7    Shen, X.8
  • 40
    • 77949261485 scopus 로고    scopus 로고
    • MicroRNAs in cancer - from research to therapy
    • Cho WC. MicroRNAs in cancer - from research to therapy. Biochim Biophys Acta 2010, 1805(2):209-217.
    • (2010) Biochim Biophys Acta , vol.1805 , Issue.2 , pp. 209-217
    • Cho, W.C.1
  • 42
    • 0030805592 scopus 로고    scopus 로고
    • Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
    • Lee J, Platt KA, Censullo P, Ruiz i Altaba A. Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 1997, 124(13):2537-2552.
    • (1997) Development , vol.124 , Issue.13 , pp. 2537-2552
    • Lee, J.1    Platt, K.A.2    Censullo, P.3    Ruiz i Altaba, A.4
  • 43
    • 34347253037 scopus 로고    scopus 로고
    • Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells
    • 10.1074/jbc.M611089200, 17353198
    • Ji Z, Mei FC, Xie J, Cheng X. Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells. J Biol Chem 2007, 282(19):14048-14055. 10.1074/jbc.M611089200, 17353198.
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14048-14055
    • Ji, Z.1    Mei, F.C.2    Xie, J.3    Cheng, X.4
  • 44
    • 40949137792 scopus 로고    scopus 로고
    • Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway
    • Yoo YA, Kang MH, Kim JS, Oh SC. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway. Carcinogenesis 2008, 29(3):480-490.
    • (2008) Carcinogenesis , vol.29 , Issue.3 , pp. 480-490
    • Yoo, Y.A.1    Kang, M.H.2    Kim, J.S.3    Oh, S.C.4
  • 45
    • 67649446810 scopus 로고    scopus 로고
    • Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals
    • Katoh Y, Katoh M. Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. Int J Oncol 2009, 35(1):187-192.
    • (2009) Int J Oncol , vol.35 , Issue.1 , pp. 187-192
    • Katoh, Y.1    Katoh, M.2
  • 46
    • 62649094925 scopus 로고    scopus 로고
    • A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
    • 10.1038/emboj.2009.16, 2647769, 19214186
    • Stecca B, Ruiz i Altaba A. A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers. EMBO J 2009, 28(6):663-676. 10.1038/emboj.2009.16, 2647769, 19214186.
    • (2009) EMBO J , vol.28 , Issue.6 , pp. 663-676
    • Stecca, B.1    Ruiz i Altaba, A.2
  • 47
    • 31544480393 scopus 로고    scopus 로고
    • Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
    • 1361531, 16158046
    • Li X, Deng W, Nail CD, Bailey SK, Kraus MH, Ruppert JM, Lobo-Ruppert SM. Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation. Oncogene 2006, 25(4):609-621. 1361531, 16158046.
    • (2006) Oncogene , vol.25 , Issue.4 , pp. 609-621
    • Li, X.1    Deng, W.2    Nail, C.D.3    Bailey, S.K.4    Kraus, M.H.5    Ruppert, J.M.6    Lobo-Ruppert, S.M.7
  • 48
    • 33947254016 scopus 로고    scopus 로고
    • Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
    • 10.1158/0008-5472.CAN-06-3281, 3073370, 17332349
    • Feldmann G, Dhara S, Fendrich V, Bedja D, Beaty R, Mullendore M, Karikari C, Alvarez H, Iacobuzio-Donahue C, Jimeno A, et al. Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 2007, 67(5):2187-2196. 10.1158/0008-5472.CAN-06-3281, 3073370, 17332349.
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 2187-2196
    • Feldmann, G.1    Dhara, S.2    Fendrich, V.3    Bedja, D.4    Beaty, R.5    Mullendore, M.6    Karikari, C.7    Alvarez, H.8    Iacobuzio-Donahue, C.9    Jimeno, A.10
  • 49
    • 78649307157 scopus 로고    scopus 로고
    • Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas
    • 10.1002/emmm.201000098, 3394505, 20941789
    • Varnat F, Siegl-Cachedenier I, Malerba M, Gervaz P, Ruiz i Altaba A. Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas. EMBO Mol Med 2010, 2(11):440-457. 10.1002/emmm.201000098, 3394505, 20941789.
    • (2010) EMBO Mol Med , vol.2 , Issue.11 , pp. 440-457
    • Varnat, F.1    Siegl-Cachedenier, I.2    Malerba, M.3    Gervaz, P.4    Ruiz i Altaba, A.5
  • 50
    • 27744583597 scopus 로고    scopus 로고
    • Hedgehog signaling pathway and gastric cancer
    • 10.4161/cbt.4.10.2184, 16258256
    • Katoh Y, Katoh M. Hedgehog signaling pathway and gastric cancer. Cancer Biol Ther 2005, 4(10):1050-1054. 10.4161/cbt.4.10.2184, 16258256.
    • (2005) Cancer Biol Ther , vol.4 , Issue.10 , pp. 1050-1054
    • Katoh, Y.1    Katoh, M.2
  • 51
    • 27144541492 scopus 로고    scopus 로고
    • Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
    • 10.1093/carcin/bgi130, 15905200
    • Ma X, Chen K, Huang S, Zhang X, Adegboyega PA, Evers BM, Zhang H, Xie J. Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas. Carcinogenesis 2005, 26(10):1698-1705. 10.1093/carcin/bgi130, 15905200.
    • (2005) Carcinogenesis , vol.26 , Issue.10 , pp. 1698-1705
    • Ma, X.1    Chen, K.2    Huang, S.3    Zhang, X.4    Adegboyega, P.A.5    Evers, B.M.6    Zhang, H.7    Xie, J.8
  • 52
    • 33746266049 scopus 로고    scopus 로고
    • Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma
    • Ma XL, Sun HI, Wang YS, Huang SH, Xie JW, Zhang HW. Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma. World J Gastroenterol 2006, 12(25):3965-3969.
    • (2006) World J Gastroenterol , vol.12 , Issue.25 , pp. 3965-3969
    • Ma, X.L.1    Sun, H.I.2    Wang, Y.S.3    Huang, S.H.4    Xie, J.W.5    Zhang, H.W.6
  • 53
    • 84877114740 scopus 로고    scopus 로고
    • MiR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer
    • 10.1007/s13277-012-0609-7, 23296701
    • Wen D, Li S, Ji F, Cao H, Jiang W, Zhu J, Fang X. miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer. Tumour Biol 2013, 34(2):793-803. 10.1007/s13277-012-0609-7, 23296701.
    • (2013) Tumour Biol , vol.34 , Issue.2 , pp. 793-803
    • Wen, D.1    Li, S.2    Ji, F.3    Cao, H.4    Jiang, W.5    Zhu, J.6    Fang, X.7


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