Synthesis and evaluation of novel cyclic peptide inhibitors of lysine-specific demethylase 1

ACS Medicinal Chemistry Letters

Volumn 5, Issue 1, 2014, Pages 29-33

  Kumarasinghe, Isuru R ^a   Woster, Patrick M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Chromatin architecture; chromatin remodeling; cyclic peptide; histone; histone 3 lysine 4; KDM inhibitors; lysine specific demethylase

Indexed keywords

CYCLOPEPTIDE; ENZYME INHIBITOR; HISTONE DEMETHYLASE; LYSINE SPECIFIC DEMETHYLASE 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; X RAY CRYSTALLOGRAPHY;

EID: 84892607526     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml4002997     Document Type: Article

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