Sigma-1 receptor antagonist, BD1047 reduces nociceptive responses and phosphorylation of p38 MAPK in mice orofacial formalin model

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 1, 2014, Pages 145-151

  Roh, Dae Hyun ^a   Yoon, Seo Yeon ^b  

^a Kyung Hee University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Formalin test; Fos protein; Orofacial pain; Sigma 1 receptor

Indexed keywords

FORMALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; PLACEBO; PROTEIN FOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; DRUG RESPONSE; DRUG SELECTIVITY; DRUG TARGETING; FACE PAIN; IMMUNOCOMPETENT CELL; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIGEMINAL NUCLEUS;

ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; ETHYLENEDIAMINES; FACIAL PAIN; FORMALDEHYDE; LIP; MALE; MICE; MICE, INBRED C57BL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, SIGMA; SIGNAL TRANSDUCTION;

EID: 84892605618     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00690     Document Type: Article

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