메뉴 건너뛰기




Volumn 10, Issue 3, 2009, Pages 253-263

Acupoint Stimulation With Diluted Bee Venom (Apipuncture) Potentiates the Analgesic Effect of Intrathecal Clonidine in the Rodent Formalin Test and in a Neuropathic Pain Model

Author keywords

2 adrenoceptor; Clonidine; diluted bee venom; formalin test; neuropathic pain

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BEE VENOM; CLONIDINE; FORMALDEHYDE; IDAZOXAN; PROTEIN FOS;

EID: 60849102766     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2008.09.002     Document Type: Article
Times cited : (42)

References (51)
  • 1
    • 0023895875 scopus 로고
    • A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
    • Bennett G.J., and Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33 (1988) 87-107
    • (1988) Pain , vol.33 , pp. 87-107
    • Bennett, G.J.1    Xie, Y.K.2
  • 3
    • 0032437213 scopus 로고    scopus 로고
    • The contribution of spinal neuronal changes to development of prolonged, tonic nociceptive responses of the cat induced by subcutaneous bee venom injection
    • Chen J., Luo C., and Li H.L. The contribution of spinal neuronal changes to development of prolonged, tonic nociceptive responses of the cat induced by subcutaneous bee venom injection. Eur J Pain 2 (1998) 359-376
    • (1998) Eur J Pain , vol.2 , pp. 359-376
    • Chen, J.1    Luo, C.2    Li, H.L.3
  • 4
    • 29144498985 scopus 로고    scopus 로고
    • Fos, nociception and the dorsal horn
    • Coggeshall R.E. Fos, nociception and the dorsal horn. Prog Neurobiol 77 (2005) 299-352
    • (2005) Prog Neurobiol , vol.77 , pp. 299-352
    • Coggeshall, R.E.1
  • 5
    • 0018717559 scopus 로고
    • Alpha 2-adrenoceptors mediate clonidine-induced sedation in the rat
    • Drew G.M., Gower A.J., and Marriott A.S. Alpha 2-adrenoceptors mediate clonidine-induced sedation in the rat. Br J Pharmacol 67 (1979) 133-141
    • (1979) Br J Pharmacol , vol.67 , pp. 133-141
    • Drew, G.M.1    Gower, A.J.2    Marriott, A.S.3
  • 6
    • 0029859756 scopus 로고    scopus 로고
    • Three novel spinal analgesics: Clonidine, neostigmine, amitriptyline
    • Eisenach J.C. Three novel spinal analgesics: Clonidine, neostigmine, amitriptyline. Reg Anesth 21 (1996) 81-83
    • (1996) Reg Anesth , vol.21 , pp. 81-83
    • Eisenach, J.C.1
  • 7
    • 39449095747 scopus 로고    scopus 로고
    • Clonidine as an adjuvant to intrathecal local anesthetics for surgery: Systematic review of randomized trials
    • Elia N., Culebras X., Mazza C., Schiffer E., and Tramer M.R. Clonidine as an adjuvant to intrathecal local anesthetics for surgery: Systematic review of randomized trials. Reg Anesth Pain Med 33 (2008) 159-167
    • (2008) Reg Anesth Pain Med , vol.33 , pp. 159-167
    • Elia, N.1    Culebras, X.2    Mazza, C.3    Schiffer, E.4    Tramer, M.R.5
  • 8
    • 0031839004 scopus 로고    scopus 로고
    • Enhanced blood pressure sensitivity to deoxycorticosterone in mice with disruption of bradykinin B2 receptor gene
    • Emanueli C., Fink E., Milia A.F., Salis M.B., Conti M., Demontis M.P., and Madeddu P. Enhanced blood pressure sensitivity to deoxycorticosterone in mice with disruption of bradykinin B2 receptor gene. Hypertension 31 (1998) 1278-1283
    • (1998) Hypertension , vol.31 , pp. 1278-1283
    • Emanueli, C.1    Fink, E.2    Milia, A.F.3    Salis, M.B.4    Conti, M.5    Demontis, M.P.6    Madeddu, P.7
  • 9
    • 0142043854 scopus 로고    scopus 로고
    • Spinal delivery of analgesics in experimental models of pain and analgesia
    • Fairbanks C.A. Spinal delivery of analgesics in experimental models of pain and analgesia. Adv Drug Deliv Rev 55 (2003) 1007-1041
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1007-1041
    • Fairbanks, C.A.1
  • 10
    • 33750428905 scopus 로고    scopus 로고
    • Systemic clonidine activates neurons of the dorsal horn, but not the locus ceruleus (A6) or the A7 area, after a formalin test: The importance of the dorsal horn in the antinociceptive effects of clonidine
    • Fukuda T., Furukawa H., Hisano S., and Toyooka H. Systemic clonidine activates neurons of the dorsal horn, but not the locus ceruleus (A6) or the A7 area, after a formalin test: The importance of the dorsal horn in the antinociceptive effects of clonidine. J Anesth 20 (2006) 279-283
    • (2006) J Anesth , vol.20 , pp. 279-283
    • Fukuda, T.1    Furukawa, H.2    Hisano, S.3    Toyooka, H.4
  • 11
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K., Dubner R., Brown F., Flores C., and Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 (1988) 77-88
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 12
    • 0031985772 scopus 로고    scopus 로고
    • Using c-fos as a neural marker of pain
    • Harris J.A. Using c-fos as a neural marker of pain. Brain Res Bull 45 (1998) 1-8
    • (1998) Brain Res Bull , vol.45 , pp. 1-8
    • Harris, J.A.1
  • 13
    • 43549108996 scopus 로고    scopus 로고
    • Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats
    • Hayashida K., Clayton B.A., Johnson J.E., and Eisenach J.C. Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats. Pain 136 (2008) 348-355
    • (2008) Pain , vol.136 , pp. 348-355
    • Hayashida, K.1    Clayton, B.A.2    Johnson, J.E.3    Eisenach, J.C.4
  • 14
    • 0018956018 scopus 로고
    • Intrathecal morphine in mice: a new technique
    • Hylden J.L., and Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur J Pharmacol 67 (1980) 313-316
    • (1980) Eur J Pharmacol , vol.67 , pp. 313-316
    • Hylden, J.L.1    Wilcox, G.L.2
  • 15
    • 0027467224 scopus 로고
    • Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse
    • Kanui T.I., Tjolsen A., Lund A., Mjellem-Joly N., and Hole K. Antinociceptive effects of intrathecal administration of alpha-adrenoceptor antagonists and clonidine in the formalin test in the mouse. Neuropharmacology 32 (1993) 367-371
    • (1993) Neuropharmacology , vol.32 , pp. 367-371
    • Kanui, T.I.1    Tjolsen, A.2    Lund, A.3    Mjellem-Joly, N.4    Hole, K.5
  • 16
    • 0037767115 scopus 로고    scopus 로고
    • Antihyperalgesic and side effects of intrathecal clonidine and tizanidine in a rat model of neuropathic pain
    • Kawamata T., Omote K., Yamamoto H., Toriyabe M., Wada K., and Namiki A. Antihyperalgesic and side effects of intrathecal clonidine and tizanidine in a rat model of neuropathic pain. Anesthesiology 98 (2003) 1480-1483
    • (2003) Anesthesiology , vol.98 , pp. 1480-1483
    • Kawamata, T.1    Omote, K.2    Yamamoto, H.3    Toriyabe, M.4    Wada, K.5    Namiki, A.6
  • 19
    • 11144314734 scopus 로고    scopus 로고
    • Antinociceptive mechanisms associated with diluted bee venom acupuncture (apipuncture) in the rat formalin test: Involvement of descending adrenergic and serotonergic pathways
    • Kim H.W., Kwon Y.B., Han H.J., Yang I.S., Beitz A.J., and Lee J.H. Antinociceptive mechanisms associated with diluted bee venom acupuncture (apipuncture) in the rat formalin test: Involvement of descending adrenergic and serotonergic pathways. Pharmacol Res 51 (2005) 183-188
    • (2005) Pharmacol Res , vol.51 , pp. 183-188
    • Kim, H.W.1    Kwon, Y.B.2    Han, H.J.3    Yang, I.S.4    Beitz, A.J.5    Lee, J.H.6
  • 21
    • 0029006463 scopus 로고
    • A noninvasive computerized tail-cuff system for measuring blood pressure in mice
    • Krege J.H., Hodgin J.B., Hagaman J.R., and Smithies O. A noninvasive computerized tail-cuff system for measuring blood pressure in mice. Hypertension 25 (1995) 1111-1115
    • (1995) Hypertension , vol.25 , pp. 1111-1115
    • Krege, J.H.1    Hodgin, J.B.2    Hagaman, J.R.3    Smithies, O.4
  • 22
    • 0035800634 scopus 로고    scopus 로고
    • Visceral antinociception produced by bee venom stimulation of the Zhongwan acupuncture point in mice: Role of alpha(2) adrenoceptors
    • Kwon Y.B., Kang M.S., Han H.J., Beitz A.J., and Lee J.H. Visceral antinociception produced by bee venom stimulation of the Zhongwan acupuncture point in mice: Role of alpha(2) adrenoceptors. Neurosci Lett 308 (2001) 133-137
    • (2001) Neurosci Lett , vol.308 , pp. 133-137
    • Kwon, Y.B.1    Kang, M.S.2    Han, H.J.3    Beitz, A.J.4    Lee, J.H.5
  • 23
    • 0035864885 scopus 로고    scopus 로고
    • Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses
    • Kwon Y.B., Lee J.D., Lee H.J., Han H.J., Mar W.C., Kang S.K., Beitz A.J., and Lee J.H. Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses. Pain 90 (2001) 271-280
    • (2001) Pain , vol.90 , pp. 271-280
    • Kwon, Y.B.1    Lee, J.D.2    Lee, H.J.3    Han, H.J.4    Mar, W.C.5    Kang, S.K.6    Beitz, A.J.7    Lee, J.H.8
  • 24
    • 3442897090 scopus 로고    scopus 로고
    • Bee venom acupoint stimulation increases Fos expression in catecholaminergic neurons in the rat brain
    • Kwon Y.B., Han H.J., Beitz A.J., and Lee J.H. Bee venom acupoint stimulation increases Fos expression in catecholaminergic neurons in the rat brain. Mol Cells 17 (2004) 329-333
    • (2004) Mol Cells , vol.17 , pp. 329-333
    • Kwon, Y.B.1    Han, H.J.2    Beitz, A.J.3    Lee, J.H.4
  • 26
    • 33646258036 scopus 로고    scopus 로고
    • Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's antiinflammatory effect
    • Kwon Y.B., Yoon S.Y., Kim H.W., Roh D.H., Kang S.Y., Ryu Y.H., Choi S.M., Han H.J., Lee H.J., Kim K.W., Beitz A.J., and Lee J.H. Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's antiinflammatory effect. Neurosci Res 55 (2006) 197-203
    • (2006) Neurosci Res , vol.55 , pp. 197-203
    • Kwon, Y.B.1    Yoon, S.Y.2    Kim, H.W.3    Roh, D.H.4    Kang, S.Y.5    Ryu, Y.H.6    Choi, S.M.7    Han, H.J.8    Lee, H.J.9    Kim, K.W.10    Beitz, A.J.11    Lee, J.H.12
  • 27
    • 0031857505 scopus 로고    scopus 로고
    • Intrathecal neostigmine, but not sympathectomy, relieves mechanical allodynia in a rat model of neuropathic pain
    • Lavand'homme P., Pan H.L., and Eisenach J.C. Intrathecal neostigmine, but not sympathectomy, relieves mechanical allodynia in a rat model of neuropathic pain. Anesthesiology 89 (1998) 493-499
    • (1998) Anesthesiology , vol.89 , pp. 493-499
    • Lavand'homme, P.1    Pan, H.L.2    Eisenach, J.C.3
  • 28
    • 0028954690 scopus 로고
    • Analysis of drug interaction between intrathecal clonidine and MK-801 in peripheral neuropathic pain rat model
    • Lee Y.W., and Yaksh T.L. Analysis of drug interaction between intrathecal clonidine and MK-801 in peripheral neuropathic pain rat model. Anesthesiology 82 (1995) 741-748
    • (1995) Anesthesiology , vol.82 , pp. 741-748
    • Lee, Y.W.1    Yaksh, T.L.2
  • 29
    • 0028922410 scopus 로고
    • A comparison of intrathecally administered narcotic and nonnarcotic analgesics for experimental chronic neuropathic pain
    • Leiphart J.W., Dills C.V., Zikel O.M., Kim D.L., and Levy R.M. A comparison of intrathecally administered narcotic and nonnarcotic analgesics for experimental chronic neuropathic pain. Journal of neurosurgery 82 (1995) 595-599
    • (1995) Journal of neurosurgery , vol.82 , pp. 595-599
    • Leiphart, J.W.1    Dills, C.V.2    Zikel, O.M.3    Kim, D.L.4    Levy, R.M.5
  • 30
    • 0032945956 scopus 로고    scopus 로고
    • Windup leads to characteristics of central sensitization
    • Li J., Simone D.A., and Larson A.A. Windup leads to characteristics of central sensitization. Pain 79 (1999) 75-82
    • (1999) Pain , vol.79 , pp. 75-82
    • Li, J.1    Simone, D.A.2    Larson, A.A.3
  • 31
    • 0034527450 scopus 로고    scopus 로고
    • The pharmacological basis of contemporary pain management
    • MacPherson R.D. The pharmacological basis of contemporary pain management. Pharmacol Therap 88 (2000) 163-185
    • (2000) Pharmacol Therap , vol.88 , pp. 163-185
    • MacPherson, R.D.1
  • 32
    • 33750728462 scopus 로고    scopus 로고
    • Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation
    • Martin T.J., Kim S.A., and Eisenach J.C. Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation. Pain 125 (2006) 257-263
    • (2006) Pain , vol.125 , pp. 257-263
    • Martin, T.J.1    Kim, S.A.2    Eisenach, J.C.3
  • 33
    • 0025903494 scopus 로고
    • Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia
    • Maze M., and Tranquilli W. Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia. Anesthesiology 74 (1991) 581-605
    • (1991) Anesthesiology , vol.74 , pp. 581-605
    • Maze, M.1    Tranquilli, W.2
  • 34
    • 0032004235 scopus 로고    scopus 로고
    • An isobolographic analysis of drug interaction between intrathecal clonidine and baclofen in the formalin test in rats
    • Przesmycki K., Dzieciuch J.A., Czuczwar S.J., and Kleinrok Z. An isobolographic analysis of drug interaction between intrathecal clonidine and baclofen in the formalin test in rats. Neuropharmacology 37 (1998) 207-214
    • (1998) Neuropharmacology , vol.37 , pp. 207-214
    • Przesmycki, K.1    Dzieciuch, J.A.2    Czuczwar, S.J.3    Kleinrok, Z.4
  • 35
    • 0031301645 scopus 로고    scopus 로고
    • Analgesic effectiveness of ketorolac compared to meperidine in the rat formalin test
    • Randolph B.C., and Peters M.A. Analgesic effectiveness of ketorolac compared to meperidine in the rat formalin test. Anesth Prog 44 (1997) 11-16
    • (1997) Anesth Prog , vol.44 , pp. 11-16
    • Randolph, B.C.1    Peters, M.A.2
  • 36
    • 0027501057 scopus 로고
    • NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw
    • Ren K., and Dubner R. NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw. Neurosci Lett 163 (1993) 22-26
    • (1993) Neurosci Lett , vol.163 , pp. 22-26
    • Ren, K.1    Dubner, R.2
  • 37
    • 4444310546 scopus 로고    scopus 로고
    • Acupoint stimulation with diluted bee venom (apipuncture) alleviates thermal hyperalgesia in a rodent neuropathic pain model: Involvement of spinal alpha 2-adrenoceptors
    • Roh D.H., Kwon Y.B., Kim H.W., Ham T.W., Yoon S.Y., Kang S.Y., Han H.J., Lee H.J., Beitz A.J., and Lee J.H. Acupoint stimulation with diluted bee venom (apipuncture) alleviates thermal hyperalgesia in a rodent neuropathic pain model: Involvement of spinal alpha 2-adrenoceptors. J Pain 5 (2004) 297-303
    • (2004) J Pain , vol.5 , pp. 297-303
    • Roh, D.H.1    Kwon, Y.B.2    Kim, H.W.3    Ham, T.W.4    Yoon, S.Y.5    Kang, S.Y.6    Han, H.J.7    Lee, H.J.8    Beitz, A.J.9    Lee, J.H.10
  • 39
    • 49949100761 scopus 로고    scopus 로고
    • Intrathecal clonidine suppresses phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain
    • Roh D.H., Kim H.W., Yoon S.Y., Seo H.S., Kwon Y.B., Han H.J., Beitz A.J., and Lee J.H. Intrathecal clonidine suppresses phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain. Anesth Analg 107 (2008) 693-700
    • (2008) Anesth Analg , vol.107 , pp. 693-700
    • Roh, D.H.1    Kim, H.W.2    Yoon, S.Y.3    Seo, H.S.4    Kwon, Y.B.5    Han, H.J.6    Beitz, A.J.7    Lee, J.H.8
  • 40
    • 0031028843 scopus 로고    scopus 로고
    • Parametric studies on electroacupuncture-like stimulation in a rat model: Effects of intensity, frequency, and duration of stimulation on evoked antinociception
    • Romita V.V., Suk A., and Henry J.L. Parametric studies on electroacupuncture-like stimulation in a rat model: Effects of intensity, frequency, and duration of stimulation on evoked antinociception. Brain Res Bull 42 (1997) 289-296
    • (1997) Brain Res Bull , vol.42 , pp. 289-296
    • Romita, V.V.1    Suk, A.2    Henry, J.L.3
  • 41
    • 0028109317 scopus 로고
    • Intrathecal morphine and clonidine in the management of spinal cord injury pain: a case report
    • Siddall P.J., Gray M., Rutkowski S., and Cousins M.J. Intrathecal morphine and clonidine in the management of spinal cord injury pain: a case report. Pain 59 (1994) 147-148
    • (1994) Pain , vol.59 , pp. 147-148
    • Siddall, P.J.1    Gray, M.2    Rutkowski, S.3    Cousins, M.J.4
  • 42
    • 0033677167 scopus 로고    scopus 로고
    • The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury
    • Siddall P.J., Molloy A.R., Walker S., Mather L.E., Rutkowski S.B., and Cousins M.J. The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury. Anesth Analg 91 (2000) 1493-1498
    • (2000) Anesth Analg , vol.91 , pp. 1493-1498
    • Siddall, P.J.1    Molloy, A.R.2    Walker, S.3    Mather, L.E.4    Rutkowski, S.B.5    Cousins, M.J.6
  • 43
    • 0019957514 scopus 로고
    • Clonidine-induced sedation in rats: Evidence for mediation by postsynaptic alpha 2-adrenoreceptors
    • Spyraki C., and Fibiger H.C. Clonidine-induced sedation in rats: Evidence for mediation by postsynaptic alpha 2-adrenoreceptors. J Neural Transm 54 (1982) 153-163
    • (1982) J Neural Transm , vol.54 , pp. 153-163
    • Spyraki, C.1    Fibiger, H.C.2
  • 44
    • 1342305375 scopus 로고    scopus 로고
    • Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia
    • Stone L.S., Fairbanks C.A., and Wilcox G.L. Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia. Ann N Y Acad Sci 1009 (2003) 378-385
    • (2003) Ann N Y Acad Sci , vol.1009 , pp. 378-385
    • Stone, L.S.1    Fairbanks, C.A.2    Wilcox, G.L.3
  • 45
    • 0027401013 scopus 로고
    • The role of clonidine in anesthesia
    • Striebel H.W., Koenigs D., and Heil T. The role of clonidine in anesthesia. Anaesthesist 42 (1993) 131-141
    • (1993) Anaesthesist , vol.42 , pp. 131-141
    • Striebel, H.W.1    Koenigs, D.2    Heil, T.3
  • 47
    • 0017652917 scopus 로고
    • Lipophilicity and brain disposition of clonidine and structurally related imidazolidines
    • Timmermans P.B., Brands A., and van Zwieten P.A. Lipophilicity and brain disposition of clonidine and structurally related imidazolidines. Naunyn Schmiedebergs Arch Pharmacol 300 (1977) 217-226
    • (1977) Naunyn Schmiedebergs Arch Pharmacol , vol.300 , pp. 217-226
    • Timmermans, P.B.1    Brands, A.2    van Zwieten, P.A.3
  • 49
    • 0036792381 scopus 로고    scopus 로고
    • Clonidine-a potent analgesic adjuvant
    • Tryba M., and Gehling M. Clonidine-a potent analgesic adjuvant. Curr Opin Anaesthesiol 15 (2002) 511-517
    • (2002) Curr Opin Anaesthesiol , vol.15 , pp. 511-517
    • Tryba, M.1    Gehling, M.2
  • 50
    • 0035432284 scopus 로고    scopus 로고
    • Synergistic effects between intrathecal clonidine and neostigmine in the formalin test
    • Yoon M.H., Yoo K.Y., and Jeong C.Y. Synergistic effects between intrathecal clonidine and neostigmine in the formalin test. J Korean Med Sci 16 (2001) 498-504
    • (2001) J Korean Med Sci , vol.16 , pp. 498-504
    • Yoon, M.H.1    Yoo, K.Y.2    Jeong, C.Y.3
  • 51
    • 0035840825 scopus 로고    scopus 로고
    • Pathobiology of neuropathic pain
    • Zimmermann M. Pathobiology of neuropathic pain. Eur J Pharmacol 429 (2001) 23-37
    • (2001) Eur J Pharmacol , vol.429 , pp. 23-37
    • Zimmermann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.