메뉴 건너뛰기




Volumn 674, Issue 2-3, 2012, Pages 234-238

The antinociceptive effect of intrathecal escin in the rat formalin test

Author keywords

c Fos; Escin; Formalin test; p p38 MAPK

Indexed keywords

ESCIN; FORMALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS;

EID: 84855556945     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.10.025     Document Type: Article
Times cited : (14)

References (34)
  • 1
    • 0031049721 scopus 로고    scopus 로고
    • Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: Studies with remifentanil and lidocaine
    • DOI 10.1016/S0304-3959(96)03285-X, PII S030439599603285X
    • Abbadie, C., Taylor, B.K., Peterson, M.A., Basbaum, A.I., 1997. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentanil and lidocaine. Pain 69, 101-110. (Pubitemid 27081414)
    • (1997) Pain , vol.69 , Issue.1-2 , pp. 101-110
    • Abbadie, C.1    Taylor, B.K.2    Peterson, M.A.3    Basbaum, A.I.4
  • 2
    • 0028833853 scopus 로고
    • The formalin test: Scoring properties of the first and second phases of the pain response in rats
    • Abbott, F.V., Franklin, K.B., Westbrook, R.F., 1995. The formalin test: scoring properties of the first and second phases of the pain response in rats. Pain 60, 91-102.
    • (1995) Pain , vol.60 , pp. 91-102
    • Abbott, F.V.1    Franklin, K.B.2    Westbrook, R.F.3
  • 3
    • 0017706269 scopus 로고
    • The mode of action of aescin and the release of prostaglandins
    • DOI 10.1016/0090-6980(77)90169-1
    • Berti, F., Omini, C., Longiave, D., 1977. The mode of action of aescin and the release of prostaglandins. Prostaglandins 14, 241-249. (Pubitemid 8171138)
    • (1977) Prostaglandins , vol.14 , Issue.2 , pp. 241-249
    • Berti, F.1    Omini, C.2    Longiave, D.3
  • 4
    • 0026647503 scopus 로고
    • The effect of stimulus duration on noxious-stimulus induced c-fos expression in the rodent spinal cord
    • Bullitt, E., Lee, C.L., Light, A.R., Willcockson, H., 1992. The effect of stimulus duration on noxious-stimulus induced c-fos expression in the rodent spinal cord. Brain Res. 580, 172-179.
    • (1992) Brain Res. , vol.580 , pp. 172-179
    • Bullitt, E.1    Lee, C.L.2    Light, A.R.3    Willcockson, H.4
  • 5
    • 0027451727 scopus 로고
    • Report of the results of a double-blind, randomized, single-dose trial of a topical 2% escin gel versus placebo in the acute treatment of experimentally-induced hematoma in volunteers
    • DOI 10.1055/s-2006-959716
    • Calabrese, C., Preston, P., 1993. Report of the results of a double-blind, randomized, single-dose trial of a topical 2% escin gel versus placebo in the acute treatment of experimentally-induced hematoma in volunteers. Planta Med. 59, 394-397. (Pubitemid 23319537)
    • (1993) Planta Medica , vol.59 , Issue.5 , pp. 394-397
    • Calabrese, C.1    Preston, P.2
  • 6
    • 0017643233 scopus 로고
    • The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats
    • DOI 10.1016/0304-3959(77)90130-0
    • Dubuisson, D., Dennis, S.G., 1977. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4, 161-174. (Pubitemid 8234766)
    • (1977) Pain , vol.4 , Issue.2 , pp. 161-174
    • Dubuisson, D.1    Dennis, S.G.2
  • 7
    • 74549130005 scopus 로고    scopus 로고
    • c-Fos and pERK,which is a bettermarker for neuronal activation and central sensitization after noxious stimulation and tissue injury?
    • Gao, Y.J., Ji, R.R., 2009. c-Fos and pERK,which is a bettermarker for neuronal activation and central sensitization after noxious stimulation and tissue injury? Open Pain J 2, 11-17.
    • (2009) Open Pain J , vol.2 , pp. 11-17
    • Gao, Y.J.1    Ji, R.R.2
  • 8
    • 65549155435 scopus 로고    scopus 로고
    • ATP induces long-termpotentiation of C-fiber-evoked field potentials in spinal dorsal horn: The roles of P2X4 receptors and p38 MAPK in microglia
    • Gong, Q.J., Li, Y.Y., Xin,W.J., Zang, Y., Ren,W.J.,Wei, X.H., Li, Y.Y., Zhang, T., Liu, X.G., 2009. ATP induces long-termpotentiation of C-fiber-evoked field potentials in spinal dorsal horn: the roles of P2X4 receptors and p38 MAPK in microglia. Glia 57, 583-591.
    • (2009) Glia , vol.57 , pp. 583-591
    • Gong, Q.J.1    Li, Y.Y.2    Xin, W.J.3    Zang, Y.4    Ren, W.J.5    Wei, X.H.6    Li, Y.Y.7    Zhang, T.8    Liu, X.G.9
  • 9
    • 0031886959 scopus 로고    scopus 로고
    • Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat
    • Hammond, D.L.,Wang, H., Nakashima, N., Basbaum, A.I., 1998. Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat. J. Pharmacol. Exp. Ther. 284, 378-387. (Pubitemid 28109569)
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.284 , Issue.1 , pp. 378-387
    • Hammond, D.L.1    Wang, H.2    Nakashima, N.3    Basbaum, A.I.4
  • 10
    • 0031985772 scopus 로고    scopus 로고
    • Using c-fos as a neural marker of pain
    • DOI 10.1016/S0361-9230(97)00277-3, PII S0361923097002773
    • Harris, J.A., 1998. Using c-fos as a neural marker of pain. Brain Res. Bull. 45, 1-8. (Pubitemid 28048761)
    • (1998) Brain Research Bulletin , vol.45 , Issue.1 , pp. 1-8
    • Harris, J.A.1
  • 11
    • 0019519939 scopus 로고
    • Effect of escin on adrenocorticotropin and corticosterone levels in rat plasma
    • Hiai, S., Yokoyama, H., Oura, H., 1981. Effect of escin on adrenocorticotropin and corticosterone levels in rat plasma. Chem. Pharm. Bull.(Tokyo) 29, 490-494. (Pubitemid 11121646)
    • (1981) Chemical and Pharmaceutical Bulletin , vol.29 , Issue.2 , pp. 490-494
    • Hiai, S.1    Yokoyama, H.2    Oura, H.3
  • 12
    • 28744435045 scopus 로고    scopus 로고
    • Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia
    • DOI 10.1111/j.1460-9568.2005.04451.x
    • Hua, X.Y., Svensson, C.I., Matsui, T., Fitzsimmons, B., Yaksh, T.L., Webb, M., 2005. Intrathecal minocycline attenuates peripheral inflammation-induced hyperalgesia by inhibiting p38 MAPK in spinal microglia. Eur. J. Neurosci. 22, 2431-2440. (Pubitemid 41758986)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.10 , pp. 2431-2440
    • Hua, X.-Y.1    Svensson, C.I.2    Matsui, T.3    Fitzsimmons, B.4    Yaksh, T.L.5    Webb, M.6
  • 13
    • 0023223448 scopus 로고
    • The formalin test in mice: Dissociation between inflammatory and non-inflammatory pain
    • DOI 10.1016/0304-3959(87)90088-1
    • Hunskaar, S., Hole, K., 1987. The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 30, 103-114. (Pubitemid 17094194)
    • (1987) Pain , vol.30 , Issue.1 , pp. 103-114
    • Hunskaar, S.1    Hole, K.2
  • 14
    • 0023277535 scopus 로고
    • Induction of c-fos-like protein in spinal cord neurons following sensory stimulation
    • DOI 10.1038/328632a0
    • Hunt, S.P., Pini, A., Evan, G., 1987. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328, 632-634. (Pubitemid 17103967)
    • (1987) Nature , vol.328 , Issue.6131 , pp. 632-634
    • Hunt, S.P.1    Pini, A.2    Evan, G.3
  • 15
    • 0028152966 scopus 로고
    • Differential effects of morphine on noxious stimulus-evoked Fos-like immunoreactivity in subpopulations of spinoparabrachial neurons
    • Jasmin, L., Wang, H., Tarczy-Hornoch, K., Levine, J.D., Basbaum, A.I., 1994. Differential effects of morphine on noxious stimulus-evoked fos-like immunoreactivity in subpopulations of spinoparabrachial neurons. J. Neurosci. 14, 7252-7260. (Pubitemid 24379737)
    • (1994) Journal of Neuroscience , vol.14 , Issue.12 , pp. 7252-7260
    • Jasmin, L.1    Wang, H.2    Tarczy-Hornoch, K.3    Levine, J.D.4    Basbaum, A.I.5
  • 16
    • 0037179755 scopus 로고    scopus 로고
    • p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • Ji, R.R., Samad, T.A., Jin, S.X., Schmoll, R., Woolf, C.J., 2002. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36, 57-68.
    • (2002) Neuron , vol.36 , pp. 57-68
    • Ji, R.R.1    Samad, T.A.2    Jin, S.X.3    Schmoll, R.4    Woolf, C.J.5
  • 18
    • 0037147689 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury
    • Kim, S.Y., Bae, J.C., Kim, J.Y., Lee, H.L., Lee, K.M., Kim, D.S., Cho, H.J., 2002. Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury. Neuroreport 13, 2483-2486.
    • (2002) Neuroreport , vol.13 , pp. 2483-2486
    • Kim, S.Y.1    Bae, J.C.2    Kim, J.Y.3    Lee, H.L.4    Lee, K.M.5    Kim, D.S.6    Cho, H.J.7
  • 19
    • 0030703606 scopus 로고    scopus 로고
    • Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals
    • Matsuda, H., Li, Y., Murakami, T., Ninomiya, K., Yamahara, J., Yoshikawa, M., 1997. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol. Pharm. Bull. 20, 1092-1095.
    • (1997) Biol. Pharm. Bull. , vol.20 , pp. 1092-1095
    • Matsuda, H.1    Li, Y.2    Murakami, T.3    Ninomiya, K.4    Yamahara, J.5    Yoshikawa, M.6
  • 20
    • 0027429186 scopus 로고
    • Spatial and temporal aspects of spinal cord and brainstem activation in the formalin pain model
    • DOI 10.1016/0301-0082(93)90044-S
    • Porro, C.A., Cavazzuti, M., 1993. Spatial and temporal aspects of spinal cord and brainstem activation in the formalin pain model. Prog. Neurobiol. 41, 565-607. (Pubitemid 23307089)
    • (1993) Progress in Neurobiology , vol.41 , Issue.5 , pp. 565-607
    • Porro, C.A.1    Cavazzuti, M.2
  • 21
    • 0025137135 scopus 로고
    • Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord
    • Presley, R.W., Menetrey, D., Levine, J.D., Basbaum, A.I., 1990. Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J. Neurosci. 10, 323-335. (Pubitemid 20059269)
    • (1990) Journal of Neuroscience , vol.10 , Issue.1 , pp. 323-335
    • Presley, R.W.1    Menetrey, D.2    Levine, J.D.3    Basbaum, A.I.4
  • 22
    • 0034828555 scopus 로고    scopus 로고
    • Aescin: Pharmacology, pharmacokinetics and therapeutic profile
    • DOI 10.1006/phrs.2001.0847
    • Sirtori, C.R., 2001. Aescin: pharmacology, pharmacokinetics and therapeutic profile. Pharmacol. Res. 44, 183-193. (Pubitemid 32889461)
    • (2001) Pharmacological Research , vol.44 , Issue.3 , pp. 183-193
    • Sirtori, C.R.1
  • 23
    • 0042267829 scopus 로고    scopus 로고
    • 2 release and thermal hyperalgesia
    • DOI 10.1097/00001756-200306110-00010
    • Svensson, C.I., Hua, X.Y., Protter, A.A., Powell, H.C., Yaksh, T.L., 2003a. Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia. Neuroreport 14, 1153-1157. (Pubitemid 36930264)
    • (2003) NeuroReport , vol.14 , Issue.8 , pp. 1153-1157
    • Svensson, C.I.1    Hua, X.-Y.2    Protter, A.A.3    Powell, H.C.4    Yaksh, T.L.5
  • 25
    • 15244340126 scopus 로고    scopus 로고
    • Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization
    • DOI 10.1111/j.1471-4159.2004.02996.x
    • Svensson, C.I., Fitzsimmons, B., Azizi, S., Powell, H.C., Hua, X.Y., Yaksh, T.L., 2005. Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization. J. Neurochem. 92, 1508-1520. (Pubitemid 40389219)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.6 , pp. 1508-1520
    • Svensson, C.I.1    Fitzsimmons, B.2    Azizi, S.3    Powell, H.C.4    Hua, X.-Y.5    Yaksh, T.L.6
  • 27
    • 0028806234 scopus 로고
    • Attenuation of c-Fos expression in the rat lumbosacral spinal cord by morphine or tramadol following noxious colorectal distention
    • Traub, R.J., Stitt, S., Gebhart, G.F., 1995. Attenuation of c-Fos expression in the rat lumbosacral spinal cord by morphine or tramadol following noxious colorectal distention. Brain Res. 701, 175-182.
    • (1995) Brain Res. , vol.701 , pp. 175-182
    • Traub, R.J.1    Stitt, S.2    Gebhart, G.F.3
  • 28
    • 55049086520 scopus 로고    scopus 로고
    • Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis
    • Wang, X.H., Xu, B., Liu, J.T., Cui, J.R., 2008. Effect of beta-escin sodium on endothelial cells proliferation, migration and apoptosis. Vascul. Pharmacol. 49, 158-165.
    • (2008) Vascul. Pharmacol. , vol.49 , pp. 158-165
    • Wang, X.H.1    Xu, B.2    Liu, J.T.3    Cui, J.R.4
  • 29
    • 70549111637 scopus 로고    scopus 로고
    • Effects of escin on acute inflammation and the immune system in mice
    • Wang, T., Fu, F., Zhang, L., Han, B., Zhu, M., Zhang, X., 2009. Effects of escin on acute inflammation and the immune system in mice. Pharmacol. Rep. 61, 697-704.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 697-704
    • Wang, T.1    Fu, F.2    Zhang, L.3    Han, B.4    Zhu, M.5    Zhang, X.6
  • 30
    • 0036089362 scopus 로고    scopus 로고
    • Escin/diethylammonium salicylate/heparin combination gels for the topical treatmentof acute impact injuries: A randomised, double blind, placebo controlled, multicentre study
    • DOI 10.1136/bjsm.36.3.183
    • Wetzel, D., Menke, W., Dieter, R., Smasal, V., Giannetti, B., Bulitta, M., 2002. Escin/ diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study. Br. J. Sports Med. 36, 183-188. (Pubitemid 34651936)
    • (2002) British Journal of Sports Medicine , vol.36 , Issue.3 , pp. 183-188
    • Wetzel, D.1    Menke, W.2    Dieter, R.3    Smasal, V.4    Giannetti, B.5    Bulitta, M.6
  • 31
    • 33749486775 scopus 로고    scopus 로고
    • Role of phosphorylation of ERK in induction and maintenance of LTP of the C-fiber evoked field potentials in spinal dorsal horn
    • DOI 10.1002/jnr.21013
    • Xin, W.J., Gong, Q.J., Xu, J.T., Yang, H.W., Zang, Y., Zhang, T., Li, Y.Y., Liu, X.G., 2006. Role of phosphorylation of ERK in induction and maintenance of LTP of the C-fiber evoked field potentials in spinal dorsal horn. J. Neurosci. Res. 84, 934-943. (Pubitemid 44521037)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.5 , pp. 934-943
    • Xin, W.-J.1    Gong, Q.-J.2    Xu, J.-T.3    Yang, H.-W.4    Zang, Y.5    Zhang, T.6    Li, Y.-Y.7    Liu, X.-G.8
  • 32
    • 79953300382 scopus 로고    scopus 로고
    • Effects of intrathecal escin and clonidine in the treatment of neuropathic pain in rats
    • Yao, X.H., Zhou, P., Huang, Y., Wang, B., Chen, C.Y., Qing, Z.H., 2009. Effects of intrathecal escin and clonidine in the treatment of neuropathic pain in rats. Nan Fang Yi Ke Da Xue Xue Bao 29, 1840-1842.
    • (2009) Nan Fang Yi Ke Da Xue Xue Bao , vol.29 , pp. 1840-1842
    • Yao, X.H.1    Zhou, P.2    Huang, Y.3    Wang, B.4    Chen, C.Y.5    Qing, Z.H.6
  • 33
    • 0041324602 scopus 로고    scopus 로고
    • Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test
    • DOI 10.1097/00000542-200309000-00027
    • Yoon, M.H., Choi, J.I., 2003. Pharmacologic interaction between cannabinoid and either clonidine or neostigmine in the rat formalin test. Anesthesiology 99, 701-707. (Pubitemid 37051987)
    • (2003) Anesthesiology , vol.99 , Issue.3 , pp. 701-707
    • Yoon, M.H.1    Choi II, J.2
  • 34
    • 0032934646 scopus 로고    scopus 로고
    • + pump inhibitor ouabain and its interaction with morphine and lidocaine in rats
    • DOI 10.1097/00000542-199902000-00026
    • Zeng, W., Dohi, S., Shimonaka, H., Asano, T., 1999. Spinal antinociceptive action of Na+ -K+ pump inhibitor ouabain and its interaction with morphine and lidocaine in rats. Anesthesiology 90, 500-508. (Pubitemid 29071520)
    • (1999) Anesthesiology , vol.90 , Issue.2 , pp. 500-508
    • Zeng, W.1    Dohi, S.2    Shimonaka, H.3    Asano, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.