Activation of src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathway

Journal of Pain

Volumn 13, Issue 10, 2012, Pages 1008-1015

  Tan, Yong Hui ^a   Li, Kai ^a   Chen, Xin Yi ^a   Cao, Ye ^a   Light, Alan R ^b   Fu, Kai Yuan ^a  

^a PEKING UNIVERSITY SCHOOL AND HOSPITAL OF STOMATOLOGY   (China)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic pain; formalin; microglia; p38 mitogen activated protein kinase; Src family kinases

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FORMALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; ENZYME ACTIVATION; FOOT; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LUMBAR SPINAL CORD; MALE; MICROGLIA; NONHUMAN; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

ANIMALS; MALE; MICROGLIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PAIN; PAIN MEASUREMENT; PHOSPHORYLATION; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPINAL CORD; SRC-FAMILY KINASES;

EID: 84866932868     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.07.010     Document Type: Article

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