The orofacial formalin test

Neuroscience and Biobehavioral Reviews

Volumn 28, Issue 2, 2004, Pages 219-226

  Raboisson, Patrick ^b   Dallel, Radhouane ^a  

^a INSERM   (France)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Animal model of tonic pain; Encoding of nociception intensity; Face rubbing; Inflammation; Nociception; Orofacial pain; Trigeminal

Indexed keywords

FORMALDEHYDE; OPIATE; SODIUM CHLORIDE;

AMPLITUDE MODULATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE EXACERBATION; FACE; HISTOLOGY; LEARNING; MALE; MEMORY; NOCICEPTION; NOCICEPTIVE RECEPTOR; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; RAT; REVIEW; SPINAL CORD NERVE CELL; STIMULUS; TISSUE INJURY; UPPER LIP;

EID: 2542479934     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2003.12.003     Document Type: Article

References (56)

1. Abbott F.V., Franklin K.B.J., Westbrook R.F. The formalin test: scoring properties of the first and second phases of the pain response in rats. Pain. 60:1995;91-102
2. Aigouy L., Fondras J.C., Pajot J., Schoeffler P., Woda A. Intrathecal midazolam versus intrathecal morphine in orofacial nociception: an experimental study in rats. Neurosci Lett. 139:1992;97-99
3. Beecher W.K. The measurement of pain: prototype for the quantitative study of subjective responses. Pharmacol Rev. 9:1957;50-209
4. Benoliel R., Wilensky A., Tal M., Eliav E. Application of a pro-inflammatory agent to the orbital portion of the rat infraorbital nerve induces changes indicative of ongoing trigeminal pain. Pain. 99:2002;567-578
5. Berridge K.C. Comparative fine structure of action: rules of form and sequence in the grooming patterns of six rodent species. Behaviour. 113:1990;21-56
6. Bohotin C., Scholsem M., Multon S., Martin D., Bohotin V., Schoenen J. Vagus nerve stimulation in awake rats reduces formalin-induced nociceptive behaviour and fos-immunoreactivity in trigeminal nucleus caudalis. Pain. 101:2003;3-12
7. Cahusac P.M.B., Morris R., Salt T.E., Hill R.G. Sensory responses of caudal trigeminal neurons to thermal and mechanical stimuli and their behavioural correlates in the rat. Neuroscience. 36:1990;543-551
8. Clavelou P., Dallel R., Orliaguet T., Woda A., Raboisson P. The orofacial formalin test in rats: effects of different formalin concentrations. Pain. 62:1995;295-301
9. Clavelou P., Pajot J., Dallel R., Raboisson P. Application of the formalin test to the study of orofacial pain in the rat. Neurosci Lett. 103:1989;349-353
10. Coderre T.J., Fundytus M.E., McKenna J.E., Dalal S., Melzack R. The formalin test: a validation of the weighted-scores method of behavioural pain rating. Pain. 54:1993;43-50
11. Coderre T.J., Melzack R. The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury. J Neurosci. 12:1992;3665-3670
12. Coderre T.J., Melzack R. The role of NMDA receptor-operated calcium channels in persistent nociception after formalin-induced tissue injury. J Neurosci. 12:1992;3671-3675
13. Dallel R., Clavelou P., Woda A. Effects of tractotomy on nociceptive reactions induced by tooth pulp stimulation in the rat. Exp Neurol. 106:1989;78-84
14. Dallel R., Raboisson P., Clavelou P., Saade M., Woda A. Evidence for a peripheral origin of the tonic nociceptive response to subcutaneous formalin. Pain. 61:1995;11-16
15. Dickenson A.H., Sullivan A.F. Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones. Neurosci Lett. 83:1987;207-211
16. Dickenson A.H., Sullivan A.F. Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin. Pain. 30:1987;349-360
17. Dubuisson D., Dennis S.G. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain. 4:1977;161-174
18. Eisenberg E., Vos B.P., Strassman A.M. The NMDA antagonist Memantine blocks pain behavior in a rat model of formalin-induced facial pain. Pain. 54:1993;301-307
19. Eisenberg E., Vos B.P., Strassman A.M. The peripheral antinociceptive effect of morphine in a rat model of facial pain. Neuroscience. 72:1996;519-525
20. Gilbert S.D., Clark T.M., Flores C.M. Antihyperalgesic activity of epibatidine in the formalin model of facial pain. Pain. 89:2001;159-165
21. Grabow T.S., Dougherty P.M. Cervicomedullary intrathecal injection of morphine produces antinociception in the orofacial formalin test in the rat. Anesthesiology. 95:2001;1427-1434
22. Grabow T.S., Dougherty P.M. Gabapentin produces dose-dependent antinociception in the orofacial formalin test in the rat. Reg Anesth Pain Med. 27:2002;277-283
23. Haley J.E., Dickenson A.H., Schachter M. Electrophysiological evidence for a role of bradykinin in chemical nociception in the rat. Neurosci Lett. 97:1989;198-202
24. Haley J.E., Sullivan A.F., Dickenson A.H. Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res. 518:1990;218-226
25. Hammond D.L. Inference of pain and its modulation from simple behaviors. Chapmann C.R., Loeser J.D. Issues in Pain Measurement. 1989;69-91 Raven Press, New York
26. Harris J.A., Westbrook R.F. Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment. Psychopharmacol (Berl). 115:1994;65-72
27. Hole K., Tjolsen A. The tail-flick and formalin tests in rodents: changes in skin temperature as a confounding factor. Pain. 53:1993;247-254
28. Klein B.G., Misra B.R., White C.F. Orofacial pain sensitivity in adult rats following neonatal infraorbital nerve transection. Behav Brain Res. 46:1991;197-201
29. Le Bars D., Gozariu M., Cadden S.W. Animal models of nociception. Pharmacol Rev. 53:2001;597-652
30. Luccarini P., Cadet R., Saade M., Woda A. Antinociceptive effect of morphine microinjections into the spinal trigeminal subnucleus oralis. Neuroreport. 6:1995;365-368
31. McHaffie J.G., Wang S., Walton N., Stein B.E., Redgrave P. Covariant maturation of nocifensive oral behaviour and c-fos expression in rat superior colliculus. Neuroscience. 109:2002;597-607
32. Miampamba M., Chéry-Croze S., Gorry F., Berger F., Chayvialle J.-A. Inflammation of the colonic wall induced by formalin as a model of acute visceral pain. Pain. 57:1994;327-334
33. Morris R., Cahusac P.M.B., Salt T.E., Morris R.G., Hill R.G. A behavioural model for the study of facial nociception and the effects of descending modulatory systems in the rat. J Neurosci Meth. 6:1982;245-252
34. Poon A., Sawynok J. Antinociception by adenosine analogs and an adenosine kinase inhibitor: dependence on formalin concentration. Eur J Pharmacol. 286:1995;177-184
35. Porro C.A., Cavazzuti M. Spatial and temporal aspects of spinal cord and brainstem activation in the formalin pain model. Prog Neurobiol. 41:1993;565-607
36. Puig S., Sorkin L.S. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain. 64:1995;345-355
37. Raboisson P., Bourdiol P., Dallel R., Clavelou P., Woda A. Responses of trigeminal subnucleus oralis nociceptive neurones to subcutaneous formalin in the rat. Neurosci Lett. 125:1991;179-182
38. Raboisson P., Dallel R., Clavelou P., Sessle B.J., Woda A. Effects of subcutaneous formalin on the activity of trigeminal brain stem nociceptive neurones in the rat. J Neurophysiol. 73:1995;496-505
39. Raboisson P, Størkson R, Berge O-G. Analysis of behavior in the formalin test: analgesic and non-analgesic effects of morphine. [Abstract] 8th World Congress on Pain 1996.
40. Rajaona J., Dallel R., Woda A. Is electrical stimulation of the rat incisor an appropriate experimental nociceptive stimulus? Exp Neurol. 93:1986;291-299
41. Rosenfeld J.P., Broton J.G., Clavier R.M. A reliable, facial nociception device for unrestrained, awake animals: effects of morphine and trigeminal complex lesions. Physiol Behav. 21:1978;287-290
42. Rosland J.H., Tjolsen A., Mæhle B., Hole K. The formalin test in mice: effect of formalin concentration. Pain. 42:1990;235-242
43. Rosland J.H. The formalin test in mice: the influence of ambient temperature. Pain. 45:1991;211-216
44. Sherrington C.S. The integrative action of the nervous system. 1947;Churchill Livingstone, London
45. Sukiennik A.W., Kream R.M. N-Methyl-D-Asppartate receptors and pain. Curr Opin Anaesthesiol. 8:1995;445-449
46. Taylor B.K., Peterson M.A., Basbaum A.I. Persistent cardiovascular and behavioral nociceptive responses to subcutaneous formalin require peripheral nerve input. J Neurosci. 15:1995;7575-7584
47. Tjølsen A., Berge O.-G., Hunskaar S., Rosland J.H., Hole K. The formalin test: an evaluation of the method. Pain. 51:1992;5-17
48. Vierck C.J., Cooper B.Y. Guidelines for assessing pain reactions and pain modulation in laboratory animal subjects. Kruger L., Liebeskind J.C. Advances in Pain Research and Therapy. 1984;305-322 Raven Press, New York
49. Vos B.P., Hans G., Adriaensen H. Behavioral assessment of facial pain in rats: face grooming patterns after painful and non-painful sensory disturbances in the territory of the rat's infraorbital nerve. Pain. 76:1998;173-178
50. Vos B.P., Strassman A.M., Maciewicz R.J. Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve. J Neurosci. 14:1994;2708-2723
51. Wang S., Redgrave P. Microinjections of muscimol into lateral superior colliculus disrupt orienting and oral movements in the formalin model of pain. Neuroscience. 81:1997;967-988
52. Wheeler-Aceto H., Cowan A. Naloxone causes apparent antinociception and pronociception simultaneously in the rat paw formalin test. Eur J Pharmacol. 236:1993;193-199
53. Wheeler-Aceto H., Cowan A. Standardization of the rat paw formalin test for the evaluation of analgesics. Psychopharmacol (Berl). 104:1991;35-44
54. Wheeler-Aceto H., Porreca F., Cowan A. The rat paw formalin test: comparison of noxious agents. Pain. 40:1990;229-238
55. Young R.F., Oleson T.D., Perryman K.M. Effect of trigeminal tractotomy on behavioral response to dental pulp stimulation in the monkey. J Neurosurg. 55:1981;420-423
56. Zimmerman M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:1983;109-110