Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration

Biomacromolecules

Volumn 15, Issue 1, 2014, Pages 350-360

  Agrawal, Ashish Kumar ^a   Harde, Harshad ^a   Thanki, Kaushik ^a   Jain, Sanyog ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FREEZE-DRIED FORMULATIONS; FUNCTIONALIZED POLYMERS; NEGATIVELY CHARGED; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; POSITIVELY CHARGED; RELATIVE BIOAVAILABILITY; TARGETING LIGANDS;

BIOCHEMISTRY; DRUG DELIVERY; INSULIN; LIGANDS; LIPOSOMES;

ORGANIC ACIDS;

ALLYLAMINE DERIVATIVE; FOLIC ACID; INSULIN; LIPOSOME; POLYACRYLIC ACID; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BODY FLUID; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG COATING; DRUG CONFORMATION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; DUODENUM; ENCAPSULATION; EX VIVO STUDY; FREEZE DRYING; HYPOGLYCEMIA; IN VIVO STUDY; LIPOSOMAL DELIVERY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE ABSORPTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS;

ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FOLIC ACID; HUMANS; INSULIN; LIPOSOMES; MALE; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84892585292     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm401580k     Document Type: Article

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