Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease

Aging Cell

Volumn 13, Issue 1, 2014, Pages 49-59

  Atherton, Joe ^a   Kurbatskaya, Ksenia ^a   Bondulich, Marie ^a   Croft, Cara L ^a   Garwood, Claire J ^a   Chhabra, Resham ^a   Wray, Selina ^a   Jeromin, Andreas ^b   Hanger, Diane P ^a   Noble, Wendy ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b NextGen Sciences DX   (United States)

Author keywords

Alzheimer's disease; Beta amyloid; Calcium; Calpain; Sodium calcium exchanger; Tau

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CALCIUM; CALPAIN 1; CALPEPTIN; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN 3; UNCLASSIFIED DRUG; ANTISENSE OLIGONUCLEOTIDE; CALCIUM BINDING PROTEIN; CALPAIN; CALPASTATIN; CASPASE 3; PROTEIN SUBUNIT; SLC38A3 PROTEIN, HUMAN; SLC8A3 PROTEIN, RAT; SPECTRIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; AUTOPSY; BRAIN CELL CULTURE; BRAIN TISSUE; CONTROLLED STUDY; CORTICOBASAL DEGENERATION; EMBRYO; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN TISSUE; NEUROTOXICITY; NONHUMAN; PARKINSONISM; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; RAT; RAT EMBRYO; AGED; ANIMAL; BRAIN; CELL CULTURE; DRUG EFFECTS; ENZYME SPECIFICITY; ENZYMOLOGY; FEMALE; GENE SILENCING; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; POSTMORTEM CHANGE; PROTEIN SUBUNIT; TAUOPATHY; TOXICITY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; CALCIUM-BINDING PROTEINS; CALPAIN; CASPASE 3; CELLS, CULTURED; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDES, ANTISENSE; POSTMORTEM CHANGES; PROTEIN SUBUNITS; RATS; SODIUM-CALCIUM EXCHANGER; SPECTRIN; SUBSTRATE SPECIFICITY; TAUOPATHIES;

EID: 84892556279     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12148     Document Type: Article

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