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Volumn 71, Issue 1, 2014, Pages 46-60

Mechanisms of inhibition of endothelial cell migration by taxanes

Author keywords

Centrosome; Dynamic instability; Focal adhesion; HUVEC; Microtubule; Mitosis

Indexed keywords

DOCETAXEL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PACLITAXEL;

EID: 84892544340     PISSN: 19493584     EISSN: 19493592     Source Type: Journal    
DOI: 10.1002/cm.21153     Document Type: Article
Times cited : (30)

References (58)
  • 1
    • 0034492210 scopus 로고    scopus 로고
    • Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration
    • Ballestrem C, Wehrle-Haller B, Hinz B, Imhof BA. 2000. Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration. Mol Biol Cell 11:2999-3012.
    • (2000) Mol Biol Cell , vol.11 , pp. 2999-3012
    • Ballestrem, C.1    Wehrle-Haller, B.2    Hinz, B.3    Imhof, B.A.4
  • 3
    • 33749565180 scopus 로고    scopus 로고
    • Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton
    • Bijman MN, van Nieuw Amerongen GP, Laurens N, van Hinsbergh VW, Boven E. 2006. Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton. Mol Cancer Ther 5(9):2348-2357.
    • (2006) Mol Cancer Ther , vol.5 , Issue.9 , pp. 2348-2357
    • Bijman, M.N.1    van Nieuw Amerongen, G.P.2    Laurens, N.3    van Hinsbergh, V.W.4    Boven, E.5
  • 4
    • 39149094614 scopus 로고    scopus 로고
    • Asymmetric focal adhesion disassembly in motile cells
    • Broussard JA, Webb DJ, Kaverina I. 2008. Asymmetric focal adhesion disassembly in motile cells. Curr Opin Cell Biol 20(1):85-90.
    • (2008) Curr Opin Cell Biol , vol.20 , Issue.1 , pp. 85-90
    • Broussard, J.A.1    Webb, D.J.2    Kaverina, I.3
  • 5
    • 0030940117 scopus 로고    scopus 로고
    • Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes
    • Derry WB, Wilson L, Khan IA, Luduena RF, Jordan MA. 1997. Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes. Biochemistry 36:3554-3562.
    • (1997) Biochemistry , vol.36 , pp. 3554-3562
    • Derry, W.B.1    Wilson, L.2    Khan, I.A.3    Luduena, R.F.4    Jordan, M.A.5
  • 6
    • 79953647554 scopus 로고    scopus 로고
    • Heterotrimeric G protein signaling in cancer cells with regard to metastasis formation
    • Entschladen F, Zanker KS, Powe DG. 2000. Heterotrimeric G protein signaling in cancer cells with regard to metastasis formation. Cell Cycle 10:1086-1091.
    • (2000) Cell Cycle , vol.10 , pp. 1086-1091
    • Entschladen, F.1    Zanker, K.S.2    Powe, D.G.3
  • 7
    • 20444370219 scopus 로고    scopus 로고
    • Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase
    • Ezratty EJ, Partridge MA, Gundersen GG. 2005. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat Cell Biol 7:581-590.
    • (2005) Nat Cell Biol , vol.7 , pp. 581-590
    • Ezratty, E.J.1    Partridge, M.A.2    Gundersen, G.G.3
  • 8
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: an organizing principle for drug discovery?
    • Folkman J. 2007. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 6(4):273-286.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.4 , pp. 273-286
    • Folkman, J.1
  • 9
    • 79959649836 scopus 로고    scopus 로고
    • Specific β-tubulin isotypes can functionally enhance or diminish epothilone B sensitivity in non-small cell lung cancer cells
    • doi: 10.1371/journal.pone.0021717.
    • Gan PP, McCarroll JA, Byrne FL, Garner J, Kavallaris M. 2011. Specific β-tubulin isotypes can functionally enhance or diminish epothilone B sensitivity in non-small cell lung cancer cells. PLoS One 6(6):e21717. doi: 10.1371/journal.pone.0021717.
    • (2011) PLoS One , vol.6 , Issue.6
    • Gan, P.P.1    McCarroll, J.A.2    Byrne, F.L.3    Garner, J.4    Kavallaris, M.5
  • 10
    • 80054705000 scopus 로고    scopus 로고
    • Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance
    • Ganguly A, Yang H, Pedroza M, Bhattacharya R, Cabral F. 2011. Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance. J Biol Chem 286(42):36378-36384.
    • (2011) J Biol Chem , vol.286 , Issue.42 , pp. 36378-36384
    • Ganguly, A.1    Yang, H.2    Pedroza, M.3    Bhattacharya, R.4    Cabral, F.5
  • 12
    • 0019791275 scopus 로고
    • Distribution of microtubule organizing centers in migrating sheets of endothelial cells
    • Gotlieb AI, May LM, Subrahmanyan L, Kalnins VI. 1991. Distribution of microtubule organizing centers in migrating sheets of endothelial cells. J Cell Biol 91(2 Pt 1):589-594.
    • (1991) J Cell Biol 91 2 , Issue.1 PART , pp. 589-594
    • Gotlieb, A.I.1    May, L.M.2    Subrahmanyan, L.3    Kalnins, V.I.4
  • 13
    • 0021752265 scopus 로고
    • Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo
    • Gundersen GG, Kalnoski MH, Bulinski JC. 1984. Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo. Cell 38(3):779-789.
    • (1984) Cell , vol.38 , Issue.3 , pp. 779-789
    • Gundersen, G.G.1    Kalnoski, M.H.2    Bulinski, J.C.3
  • 14
    • 0023371190 scopus 로고
    • Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules
    • Gundersen GG, Khawaja S, Bulinski JC. 1987. Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules. J Cell Biol 105(1):251-264.
    • (1987) J Cell Biol , vol.105 , Issue.1 , pp. 251-264
    • Gundersen, G.G.1    Khawaja, S.2    Bulinski, J.C.3
  • 15
    • 0141725730 scopus 로고    scopus 로고
    • Mode of action of docetaxel-a basis for combination with novel anticancer agents
    • Herbst RS, Khuri FR. 2003. Mode of action of docetaxel-a basis for combination with novel anticancer agents. Cancer Treat Rev 29(5):407-415.
    • (2003) Cancer Treat Rev , vol.29 , Issue.5 , pp. 407-415
    • Herbst, R.S.1    Khuri, F.R.2
  • 16
    • 0038105608 scopus 로고    scopus 로고
    • Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): association with impaired repositioning of the microtubule organizing center
    • Hotchkiss KA, Ashton AW, Mahmood R, Russell RG, Sparano JA, Schwartz EL. 2002. Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): association with impaired repositioning of the microtubule organizing center. Mol Cancer Ther 1(13):1191-2000.
    • (2002) Mol Cancer Ther , vol.1 , Issue.13 , pp. 1191-2000
    • Hotchkiss, K.A.1    Ashton, A.W.2    Mahmood, R.3    Russell, R.G.4    Sparano, J.A.5    Schwartz, E.L.6
  • 17
    • 0036083301 scopus 로고    scopus 로고
    • Mechanism of action of antitumor drugs that interact with microtubules and tubulin
    • Jordan MA. 2002. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anti-Cancer Agents 2:1-17.
    • (2002) Curr Med Chem Anti-Cancer Agents , vol.2 , pp. 1-17
    • Jordan, M.A.1
  • 18
    • 0032621410 scopus 로고    scopus 로고
    • The use and action of drugs in analyzing mitosis
    • Rieder C, editor. San Diego: Academic Press
    • Jordan MA, Wilson L. 1999. The use and action of drugs in analyzing mitosis. In: Rieder C, editor. Methods in Cell Biology. San Diego: Academic Press, Vol. 61. pp 267-295.
    • (1999) Methods in Cell Biology , vol.61 , pp. 267-295
    • Jordan, M.A.1    Wilson, L.2
  • 19
    • 1942438028 scopus 로고    scopus 로고
    • Microtubules as a target for anticancer drugs
    • Jordan MA, Wilson L. 2004. Microtubules as a target for anticancer drugs. Nat Rev Cancer 4(4):253-265.
    • (2004) Nat Rev Cancer , vol.4 , Issue.4 , pp. 253-265
    • Jordan, M.A.1    Wilson, L.2
  • 20
    • 0027360552 scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
    • Jordan MA, Toso RJ, Thrower D, Wilson L. 1993. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 90:9552-9556.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9552-9556
    • Jordan, M.A.1    Toso, R.J.2    Thrower, D.3    Wilson, L.4
  • 21
    • 0030020158 scopus 로고    scopus 로고
    • Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
    • Jordan MA, Wendell, K, Gardiner S, Derry B, Copp H, Wilson L. 1996. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56:816-825.
    • (1996) Cancer Res , vol.56 , pp. 816-825
    • Jordan, M.A.1    Wendell, K.2    Gardiner, S.3    Derry, B.4    Copp, H.5    Wilson, L.6
  • 22
    • 16844365749 scopus 로고    scopus 로고
    • BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability
    • Kamath K, Wilson L, Cabral F, Jordan MA. 2005. BetaIII-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability. J Biol Chem 280(13):12902-12907.
    • (2005) J Biol Chem , vol.280 , Issue.13 , pp. 12902-12907
    • Kamath, K.1    Wilson, L.2    Cabral, F.3    Jordan, M.A.4
  • 23
    • 0032514208 scopus 로고    scopus 로고
    • Targeting, capture, and stabilization of microtubules at early focal adhesions
    • Kaverina I, Rottner K, Small JV. 1998. Targeting, capture, and stabilization of microtubules at early focal adhesions. J Cell Biol 142:181-190.
    • (1998) J Cell Biol , vol.142 , pp. 181-190
    • Kaverina, I.1    Rottner, K.2    Small, J.V.3
  • 24
    • 0032872870 scopus 로고    scopus 로고
    • Microtubule targeting of substrate contacts promotes their relaxation and dissociation
    • Kaverina I, Krylyshkina O, Small JV. 1999. Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J Cell Biol 146(5):1033-1044.
    • (1999) J Cell Biol , vol.146 , Issue.5 , pp. 1033-1044
    • Kaverina, I.1    Krylyshkina, O.2    Small, J.V.3
  • 25
    • 0023877365 scopus 로고
    • Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level
    • Khawaja S, Gundersen GG, Bulinski JC. 1988. Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level. J Cell Biol 106(1):141-149.
    • (1988) J Cell Biol , vol.106 , Issue.1 , pp. 141-149
    • Khawaja, S.1    Gundersen, G.G.2    Bulinski, J.C.3
  • 26
    • 79953237846 scopus 로고    scopus 로고
    • Mitosis is not a key target of microtubule agents in patient tumors
    • Komlodi-Pasztor E, Sackett D, Wilkerson J, Fojo T. 2011. Mitosis is not a key target of microtubule agents in patient tumors. Nat Rev Clin Oncol 8(4):244-250.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.4 , pp. 244-250
    • Komlodi-Pasztor, E.1    Sackett, D.2    Wilkerson, J.3    Fojo, T.4
  • 27
    • 0023403268 scopus 로고
    • Microtubules containing detyrosinated tubulin are less dynamic
    • Kreis TE. 1987. Microtubules containing detyrosinated tubulin are less dynamic. EMBO J 6(9):2597-2606.
    • (1987) EMBO J , vol.6 , Issue.9 , pp. 2597-2606
    • Kreis, T.E.1
  • 28
    • 0036228955 scopus 로고    scopus 로고
    • Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    • Krendel M, Zenke FT, Bokoch GM. 2002. Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton. Nat Cell Biol 4:294-301.
    • (2002) Nat Cell Biol , vol.4 , pp. 294-301
    • Krendel, M.1    Zenke, F.T.2    Bokoch, G.M.3
  • 31
    • 0020316410 scopus 로고
    • Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound
    • Kupfer A, Louvard D, Singer SJ. 1982. Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc Natl Acad Sci USA 79:2603-2607.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2603-2607
    • Kupfer, A.1    Louvard, D.2    Singer, S.J.3
  • 32
    • 84879214561 scopus 로고    scopus 로고
    • Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy
    • LaPointe NE, Morfini G, Brady ST, Feinstein SC, Wilson L, Jordan MA. 2013. Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy. NeuroToxicology 37:231-239.
    • (2013) NeuroToxicology , vol.37 , pp. 231-239
    • LaPointe, N.E.1    Morfini, G.2    Brady, S.T.3    Feinstein, S.C.4    Wilson, L.5    Jordan, M.A.6
  • 33
    • 0028857104 scopus 로고
    • Low concentrations of of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion
    • Liao G, Nagasaki T, Gundersen GG. 1995. Low concentrations of of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion. J Cell Sci 108:3473-3483.
    • (1995) J Cell Sci , vol.108 , pp. 3473-3483
    • Liao, G.1    Nagasaki, T.2    Gundersen, G.G.3
  • 34
    • 33645103854 scopus 로고    scopus 로고
    • The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with docetaxel (Taxotere)
    • Lu H, Murtagh J, Schwartz EL. 2006. The microtubule binding drug laulimalide inhibits vascular endothelial growth factor-induced human endothelial cell migration and is synergistic when combined with docetaxel (Taxotere). Mol Pharmacol 69:1207-1215.
    • (2006) Mol Pharmacol , vol.69 , pp. 1207-1215
    • Lu, H.1    Murtagh, J.2    Schwartz, E.L.3
  • 36
    • 0021686169 scopus 로고
    • Dynamic instability of microtubule growth
    • Mitchison TJ, Kirschner M. 1984. Dynamic instability of microtubule growth. Nature 312:237-242.
    • (1984) Nature , vol.312 , pp. 237-242
    • Mitchison, T.J.1    Kirschner, M.2
  • 37
    • 84879236626 scopus 로고    scopus 로고
    • Naturally derived factors and their role in the promotion of angiogenesis for the healing of chronic wounds
    • Morgan C, Nigam Y. 2013. Naturally derived factors and their role in the promotion of angiogenesis for the healing of chronic wounds. Angiogenesis 16:493-502.
    • (2013) Angiogenesis , vol.16 , pp. 493-502
    • Morgan, C.1    Nigam, Y.2
  • 38
    • 33748047460 scopus 로고    scopus 로고
    • Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation
    • Murtagh J, Lu H, Schwartz EL. 2006. Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation. Cancer Res 66(16):8192-8199.
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 8192-8199
    • Murtagh, J.1    Lu, H.2    Schwartz, E.L.3
  • 40
    • 4644314377 scopus 로고    scopus 로고
    • Microtubule-actin cross-talk at focal adhesions
    • Palazzo AF, Gundersen GG. 2002. Microtubule-actin cross-talk at focal adhesions. Sci STKE 2002:pe31. http://www.stke.org/cgi/content/full/sigtrans;2002/139/pe31.
    • (2002) Sci STKE , vol.2002
    • Palazzo, A.F.1    Gundersen, G.G.2
  • 42
    • 16844381714 scopus 로고    scopus 로고
    • Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells
    • Pasquier E, Honore S, Pourroy B, Jordan MA, Lehmann M, Briand C, Braguer D. 2005. Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells. Cancer Res 65(6):2433-2440.
    • (2005) Cancer Res , vol.65 , Issue.6 , pp. 2433-2440
    • Pasquier, E.1    Honore, S.2    Pourroy, B.3    Jordan, M.A.4    Lehmann, M.5    Briand, C.6    Braguer, D.7
  • 43
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton EMBO J
    • Ren XD, Kiosses WB, Schwartz MA. 1999. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton EMBO J. 18(3):578-585.
    • (1999) 18(3) , pp. 578-585
    • Ren, X.D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 44
    • 33748994545 scopus 로고    scopus 로고
    • Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
    • Ridley AJ. 2006. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 16:522-529.
    • (2006) Trends Cell Biol , vol.16 , pp. 522-529
    • Ridley, A.J.1
  • 45
    • 77950369457 scopus 로고    scopus 로고
    • The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly
    • Rooney C, White G, Nazgiewicz A, Woodcock SA, Anderson KI, Ballestrem C, Malliri A. 2010. The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly. EMBO Rep 11(4):292-298.
    • (2010) EMBO Rep , vol.11 , Issue.4 , pp. 292-298
    • Rooney, C.1    White, G.2    Nazgiewicz, A.3    Woodcock, S.A.4    Anderson, K.I.5    Ballestrem, C.6    Malliri, A.7
  • 46
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents
    • Rowinsky EK. 1997. The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents. Annu Rev Med 48:353-374.
    • (1997) Annu Rev Med , vol.48 , pp. 353-374
    • Rowinsky, E.K.1
  • 47
    • 0034715923 scopus 로고    scopus 로고
    • Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics
    • Sastry SK, Burridge K. 2000. Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. Exp Cell Res 261:25-36.
    • (2000) Exp Cell Res , vol.261 , pp. 25-36
    • Sastry, S.K.1    Burridge, K.2
  • 48
    • 0000297058 scopus 로고
    • Taxol stabilizes microtubules in mouse fibroblast cells
    • Schiff PB, Horwitz SB. 1980. Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci USA 77:1561-1565.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1561-1565
    • Schiff, P.B.1    Horwitz, S.B.2
  • 49
    • 0023608861 scopus 로고
    • Posttranslational modification and microtubule stability
    • Schulze E, Asai DJ, Bulinski JC, Kirschner M. 1987. Posttranslational modification and microtubule stability. J Cell Biol 105:2167-2177.
    • (1987) J Cell Biol , vol.105 , pp. 2167-2177
    • Schulze, E.1    Asai, D.J.2    Bulinski, J.C.3    Kirschner, M.4
  • 51
    • 84866415731 scopus 로고    scopus 로고
    • Androgen receptor on the move: boarding the microtubule expressway to the nucleus
    • Thadani-Mulero M, Nanus DM, Giannakakou P. 2012. Androgen receptor on the move: boarding the microtubule expressway to the nucleus. Cancer Res 72:4611-4615.
    • (2012) Cancer Res , vol.72 , pp. 4611-4615
    • Thadani-Mulero, M.1    Nanus, D.M.2    Giannakakou, P.3
  • 52
    • 36049026898 scopus 로고    scopus 로고
    • Microtubule-based nuclear movement occurs independently of centrosome positioning in migrating neurons
    • Umeshima H, Hirano T, Kengaku M. 2007. Microtubule-based nuclear movement occurs independently of centrosome positioning in migrating neurons. Proc Natl Acad Sci USA 104:16182-16187.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16182-16187
    • Umeshima, H.1    Hirano, T.2    Kengaku, M.3
  • 55
    • 0036222784 scopus 로고    scopus 로고
    • Adhesion assembly, disassembly and turnover in migrating cells-over and over and over again
    • Webb DJ, Parsons JT, Horwitz AF. 2002. Adhesion assembly, disassembly and turnover in migrating cells-over and over and over again. Nat Cell Biol 4:E97-E100.
    • (2002) Nat Cell Biol , vol.4
    • Webb, D.J.1    Parsons, J.T.2    Horwitz, A.F.3
  • 57
    • 77957793033 scopus 로고    scopus 로고
    • Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs
    • Yang H, Ganguly A, Cabral F. 2010. Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs. J Biol Chem 285:32242-32250.
    • (2010) J Biol Chem , vol.285 , pp. 32242-32250
    • Yang, H.1    Ganguly, A.2    Cabral, F.3


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