The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

EMBO Reports

Volumn 11, Issue 4, 2010, Pages 292-298

  Rooney, Claire ^a   White, Gavin ^a   Nazgiewicz, Alicja ^b   Woodcock, Simon A ^a   Anderson, Kurt I ^c   Ballestrem, Christoph ^b   Malliri, Angeliki ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Focal adhesions; Microtubules; Rac; STEF; Tiam2

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; NOCODAZOLE; RAC PROTEIN; SIF GUANINE NUCLEOTIDE EXCHANGE FACTOR; TIAM1 LIKE EXCHANGE FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ENLARGEMENT; CELL GROWTH; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; FOCAL ADHESION; MICROTUBULE; MICROTUBULE ASSEMBLY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; FOCAL ADHESIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MICE; MICROSCOPY, FLUORESCENCE; MICROTUBULES; NOCODAZOLE; RAC GTP-BINDING PROTEINS; RNA INTERFERENCE;

EID: 77950369457     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2010.10     Document Type: Article

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