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Volumn 592, Issue 2, 2014, Pages 377-390

Maximal heart rate does not limit cardiovascular capacity in healthy humans: Insight from right atrial pacing during maximal exercise

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CATECHOLAMINE;

EID: 84892445064     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.262246     Document Type: Article
Times cited : (50)

References (56)
  • 1
    • 0022270890 scopus 로고
    • Maximal perfusion of skeletal muscle in man
    • Andersen P & Saltin B (1985). Maximal perfusion of skeletal muscle in man. J Physiol 366, 233-249.
    • (1985) J Physiol , vol.366 , pp. 233-249
    • Andersen, P.1    Saltin, B.2
  • 3
    • 84859707251 scopus 로고    scopus 로고
    • Peripheral vasodilation determines cardiac output in exercising humans: insight from atrial pacing
    • Bada AA, Svendsen JH, Secher NH, Saltin B & Mortensen SP (2012). Peripheral vasodilation determines cardiac output in exercising humans: insight from atrial pacing. J Physiol 590, 2051-2060.
    • (2012) J Physiol , vol.590 , pp. 2051-2060
    • Bada, A.A.1    Svendsen, J.H.2    Secher, N.H.3    Saltin, B.4    Mortensen, S.P.5
  • 4
    • 0034982960 scopus 로고    scopus 로고
    • Ventricular interaction: from bench to bedside
    • Belenkie I, Smith ER & Tyberg JV (2001). Ventricular interaction: from bench to bedside. Ann Med 33, 236-241.
    • (2001) Ann Med , vol.33 , pp. 236-241
    • Belenkie, I.1    Smith, E.R.2    Tyberg, J.V.3
  • 5
    • 0014075829 scopus 로고
    • Regulation of the circulation during exercise in man
    • Bevegard BS & Shepherd JT (1967). Regulation of the circulation during exercise in man. Physiol Rev 47, 178-213.
    • (1967) Physiol Rev , vol.47 , pp. 178-213
    • Bevegard, B.S.1    Shepherd, J.T.2
  • 6
    • 0000112876 scopus 로고
    • Determinants of duration and mean rate of ventricular ejection
    • Braunwald E, Sarnoff SJ & Stainsby WN (1958). Determinants of duration and mean rate of ventricular ejection. Circ Res 6, 319-325.
    • (1958) Circ Res , vol.6 , pp. 319-325
    • Braunwald, E.1    Sarnoff, S.J.2    Stainsby, W.N.3
  • 7
    • 33846863143 scopus 로고    scopus 로고
    • Maximal oxygen uptake is not limited by a central nervous system governor
    • Brink-Elfegoun T, Kaijser L, Gustafsson T & Ekblom B (2007). Maximal oxygen uptake is not limited by a central nervous system governor. J Appl Physiol 102, 781-786.
    • (2007) J Appl Physiol , vol.102 , pp. 781-786
    • Brink-Elfegoun, T.1    Kaijser, L.2    Gustafsson, T.3    Ekblom, B.4
  • 9
    • 0020636610 scopus 로고
    • The effect of ventilation on the accuracy of pulmonary artery and wedge pressure measurements
    • Cengiz M, Crapo RO & Gardner RM (1983). The effect of ventilation on the accuracy of pulmonary artery and wedge pressure measurements. Crit Care Med 11, 502-507.
    • (1983) Crit Care Med , vol.11 , pp. 502-507
    • Cengiz, M.1    Crapo, R.O.2    Gardner, R.M.3
  • 10
    • 0015236415 scopus 로고
    • Filling pressures in the right and left sides of the heart in acute myocardial infarction. A reappraisal of central-venous-pressure monitoring
    • Forrester JS, Diamond G, McHugh TJ & Swan HJ (1971). Filling pressures in the right and left sides of the heart in acute myocardial infarction. A reappraisal of central-venous-pressure monitoring. N Engl J Med 285, 190-193.
    • (1971) N Engl J Med , vol.285 , pp. 190-193
    • Forrester, J.S.1    Diamond, G.2    McHugh, T.J.3    Swan, H.J.4
  • 12
    • 0037448790 scopus 로고    scopus 로고
    • Reductions in systemic and skeletal muscle blood flow and oxygen delivery limit maximal aerobic capacity in humans
    • González-Alonso J & Calbet JA (2003). Reductions in systemic and skeletal muscle blood flow and oxygen delivery limit maximal aerobic capacity in humans. Circulation 107, 824-830.
    • (2003) Circulation , vol.107 , pp. 824-830
    • González-Alonso, J.1    Calbet, J.A.2
  • 14
    • 33645319183 scopus 로고    scopus 로고
    • Erythrocytes and the regulation of human skeletal muscle blood flow and oxygen delivery: role of erythrocyte count and oxygenation state of haemoglobin
    • González-Alonso J, Mortensen SP, Dawson EA, Secher NH & Damsgaard R (2006). Erythrocytes and the regulation of human skeletal muscle blood flow and oxygen delivery: role of erythrocyte count and oxygenation state of haemoglobin. J Physiol 572, 295-305.
    • (2006) J Physiol , vol.572 , pp. 295-305
    • González-Alonso, J.1    Mortensen, S.P.2    Dawson, E.A.3    Secher, N.H.4    Damsgaard, R.5
  • 15
    • 42949127088 scopus 로고    scopus 로고
    • Haemodynamic responses to exercise, ATP infusion and thigh compression in humans: insight into the role of muscle mechanisms on cardiovascular function
    • González-Alonso J, Mortensen SP, Jeppesen TD, Ali L, Barker H, Damsgaard R, Secher NH, Dawson EA & Dufour SP (2008). Haemodynamic responses to exercise, ATP infusion and thigh compression in humans: insight into the role of muscle mechanisms on cardiovascular function. J Physiol 586, 2405-2417.
    • (2008) J Physiol , vol.586 , pp. 2405-2417
    • González-Alonso, J.1    Mortensen, S.P.2    Jeppesen, T.D.3    Ali, L.4    Barker, H.5    Damsgaard, R.6    Secher, N.H.7    Dawson, E.A.8    Dufour, S.P.9
  • 16
    • 0014201127 scopus 로고
    • Regulation of cardiac output
    • Guyton AC (1967). Regulation of cardiac output. N Engl J Med 277, 805-812.
    • (1967) N Engl J Med , vol.277 , pp. 805-812
    • Guyton, A.C.1
  • 17
    • 0000757505 scopus 로고
    • Instantaneous increase in mean circulatory pressure and cardiac output at onset of muscular activity
    • Guyton AC, Douglas BH, Langston JB & Richardson TQ (1962). Instantaneous increase in mean circulatory pressure and cardiac output at onset of muscular activity. Circ Res 11, 431-441.
    • (1962) Circ Res , vol.11 , pp. 431-441
    • Guyton, A.C.1    Douglas, B.H.2    Langston, J.B.3    Richardson, T.Q.4
  • 18
    • 0021966454 scopus 로고
    • Normal and abnormal heart rate responses to exercise
    • Hammond HK & Froelicher VF (1985). Normal and abnormal heart rate responses to exercise. Prog Cardiovasc Dis 27, 271-296.
    • (1985) Prog Cardiovasc Dis , vol.27 , pp. 271-296
    • Hammond, H.K.1    Froelicher, V.F.2
  • 19
    • 84871077211 scopus 로고    scopus 로고
    • Vasodilator interactions in skeletal muscle blood flow regulation
    • Hellsten Y, Nyberg M, Jensen LG & Mortensen SP (2012). Vasodilator interactions in skeletal muscle blood flow regulation. J Physiol 590, 6297-6305.
    • (2012) J Physiol , vol.590 , pp. 6297-6305
    • Hellsten, Y.1    Nyberg, M.2    Jensen, L.G.3    Mortensen, S.P.4
  • 22
    • 37749040527 scopus 로고    scopus 로고
    • V̇O2 max: What do we know, and what do we still need to know
    • Levine BD (2008). V̇O2 max: What do we know, and what do we still need to know? J Physiol 586, 25-34.
    • (2008) J Physiol , vol.586 , pp. 25-34
    • Levine, B.D.1
  • 23
    • 2642658089 scopus 로고
    • The inotropic state of the heart
    • ed. Linden R - Churchill Livingstone, New York.
    • Linden R & Snow H (1974). The inotropic state of the heart. In Recent Advances in Physiology, ed. Linden R, pp. 148-190. Churchill Livingstone, New York.
    • (1974) Recent Advances in Physiology , pp. 148-190
    • Linden, R.1    Snow, H.2
  • 25
    • 0005332280 scopus 로고
    • Effect of ventricular rate on the cardiac output in the dog with chronic heart block
    • Miller DE, Gleason WL, Whalen RE, Morris JJ & Mclntosh HD (1962). Effect of ventricular rate on the cardiac output in the dog with chronic heart block. Circ Res 10, 658-663.
    • (1962) Circ Res , vol.10 , pp. 658-663
    • Miller, D.E.1    Gleason, W.L.2    Whalen, R.E.3    Morris, J.J.4    Mclntosh, H.D.5
  • 26
    • 33745858991 scopus 로고    scopus 로고
    • Expiratory threshold loading impairs cardiovascular function in health and chronic heart failure during submaximal exercise
    • Miller JD, Hemauer SJ, Smith CA, Stickland MK & Dempsey JA (2006). Expiratory threshold loading impairs cardiovascular function in health and chronic heart failure during submaximal exercise. J Appl Physiol 101, 213-227.
    • (2006) J Appl Physiol , vol.101 , pp. 213-227
    • Miller, J.D.1    Hemauer, S.J.2    Smith, C.A.3    Stickland, M.K.4    Dempsey, J.A.5
  • 27
    • 0000265580 scopus 로고
    • The transport function of the atrium. Factors influencing the relation between mean left atrial pressure and left ventricular end diastolic pressure
    • Mitchell JH, Gilmore JP & Sarnoff SJ (1962). The transport function of the atrium. Factors influencing the relation between mean left atrial pressure and left ventricular end diastolic pressure. Am J Cardiol 9, 237-247.
    • (1962) Am J Cardiol , vol.9 , pp. 237-247
    • Mitchell, J.H.1    Gilmore, J.P.2    Sarnoff, S.J.3
  • 28
    • 43749105804 scopus 로고    scopus 로고
    • Restrictions in systemic and locomotor skeletal muscle perfusion, oxygen supply and V̇O2 during high-intensity whole-body exercise in humans
    • Mortensen SP, Damsgaard R, Dawson EA, Secher NH & González-Alonso J (2008). Restrictions in systemic and locomotor skeletal muscle perfusion, oxygen supply and V̇O2 during high-intensity whole-body exercise in humans. J Physiol 586, 2621-2635.
    • (2008) J Physiol , vol.586 , pp. 2621-2635
    • Mortensen, S.P.1    Damsgaard, R.2    Dawson, E.A.3    Secher, N.H.4    González-Alonso, J.5
  • 30
    • 34249745856 scopus 로고    scopus 로고
    • Inhibition of nitric oxide and prostaglandins, but not endothelial-derived hyperpolarizing factors, reduces blood flow and aerobic energy turnover in the exercising human leg
    • Mortensen SP, González-Alonso J, Damsgaard R, Saltin B & Hellsten Y (2007). Inhibition of nitric oxide and prostaglandins, but not endothelial-derived hyperpolarizing factors, reduces blood flow and aerobic energy turnover in the exercising human leg. J Physiol 581, 853-861.
    • (2007) J Physiol , vol.581 , pp. 853-861
    • Mortensen, S.P.1    González-Alonso, J.2    Damsgaard, R.3    Saltin, B.4    Hellsten, Y.5
  • 31
    • 84876677794 scopus 로고    scopus 로고
    • Skeletal muscle signaling and the heart rate and blood pressure response to exercise: insight from heart rate pacing during exercise with a trained and a deconditioned muscle group
    • Mortensen SP, Svendsen JH, Ersbøll M, Hellsten Y, Secher NH & Saltin B (2013). Skeletal muscle signaling and the heart rate and blood pressure response to exercise: insight from heart rate pacing during exercise with a trained and a deconditioned muscle group. Hypertension 61, 1126-1133.
    • (2013) Hypertension , vol.61 , pp. 1126-1133
    • Mortensen, S.P.1    Svendsen, J.H.2    Ersbøll, M.3    Hellsten, Y.4    Secher, N.H.5    Saltin, B.6
  • 33
    • 37249072979 scopus 로고    scopus 로고
    • Arterial oxygenation, central motor output and exercise performance in humans
    • Noakes TD & Marino FE (2007). Arterial oxygenation, central motor output and exercise performance in humans. J Physiol 585, 919-921.
    • (2007) J Physiol , vol.585 , pp. 919-921
    • Noakes, T.D.1    Marino, F.E.2
  • 35
    • 0015014274 scopus 로고
    • Analysis of left ventricular function by atrial pacing
    • Parker JO, Khaja F & Case RB (1971). Analysis of left ventricular function by atrial pacing. Circulation 43, 241-252.
    • (1971) Circulation , vol.43 , pp. 241-252
    • Parker, J.O.1    Khaja, F.2    Case, R.B.3
  • 37
    • 0018851902 scopus 로고
    • Left ventricular performance in normal subjects: a comparison of the responses to exercise in the upright and supine positions
    • Poliner LR, Dehmer GJ, Lewis SE, Parkey RW, Blomqvist CG & Willerson JT (1980). Left ventricular performance in normal subjects: a comparison of the responses to exercise in the upright and supine positions. Circulation 62, 528-534.
    • (1980) Circulation , vol.62 , pp. 528-534
    • Poliner, L.R.1    Dehmer, G.J.2    Lewis, S.E.3    Parkey, R.W.4    Blomqvist, C.G.5    Willerson, J.T.6
  • 39
    • 4043183981 scopus 로고    scopus 로고
    • Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscle
    • Rosenmeier JB, Hansen J & González-Alonso J (2004). Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscle. J Physiol 558, 351-365.
    • (2004) J Physiol , vol.558 , pp. 351-365
    • Rosenmeier, J.B.1    Hansen, J.2    González-Alonso, J.3
  • 40
    • 54049092445 scopus 로고    scopus 로고
    • Activation of ATP/UTP selective receptors increase blood flow and blunt sympathetic vasoconstriction in human skeletal muscle
    • Rosenmeier JB, Yegutkin GG & Gonzalez-Alonso J (2008). Activation of ATP/UTP selective receptors increase blood flow and blunt sympathetic vasoconstriction in human skeletal muscle. J Physiol 586, 4993-5002.
    • (2008) J Physiol , vol.586 , pp. 4993-5002
    • Rosenmeier, J.B.1    Yegutkin, G.G.2    Gonzalez-Alonso, J.3
  • 41
    • 0016158329 scopus 로고
    • Human cardiovascular adjustments to exercise and thermal stress
    • Rowell LB (1974). Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev 54, 75-159.
    • (1974) Physiol Rev , vol.54 , pp. 75-159
    • Rowell, L.B.1
  • 42
    • 73449114826 scopus 로고
    • Human cardiovascular control
    • Rowell LB (1993). Human cardiovascular control. Ann Intern Med 119, 1234-123b.
    • (1993) Ann Intern Med , vol.119
    • Rowell, L.B.1
  • 43
    • 84871055884 scopus 로고    scopus 로고
    • Inefficient functional sympatholysis is an overlooked cause of malperfusion in contracting skeletal muscle
    • Saltin B & Mortensen SP (2012). Inefficient functional sympatholysis is an overlooked cause of malperfusion in contracting skeletal muscle. J Physiol 590, 6269-6275.
    • (2012) J Physiol , vol.590 , pp. 6269-6275
    • Saltin, B.1    Mortensen, S.P.2
  • 44
    • 85047680684 scopus 로고
    • Review: Relation between beat interval and force of the heartbeat and its clinical implications
    • Seed WA & Walker JM (1988). Review: Relation between beat interval and force of the heartbeat and its clinical implications. Cardiovasc Res 22, 303-314.
    • (1988) Cardiovasc Res , vol.22 , pp. 303-314
    • Seed, W.A.1    Walker, J.M.2
  • 45
    • 0015900229 scopus 로고
    • Local control of tissue oxygen delivery and its contribution to the regulation of cardiac output
    • Shepherd AP, Granger HJ, Smith EE & Guyton AC (1973). Local control of tissue oxygen delivery and its contribution to the regulation of cardiac output. Am J Physiol 225, 747-755.
    • (1973) Am J Physiol , vol.225 , pp. 747-755
    • Shepherd, A.P.1    Granger, H.J.2    Smith, E.E.3    Guyton, A.C.4
  • 46
    • 0027209492 scopus 로고
    • Dependence of cardiac filling pressure on cardiac output during rest and dynamic exercise in dogs
    • Sheriff DD, Zhou XP, Scher AM & Rowell LB (1993). Dependence of cardiac filling pressure on cardiac output during rest and dynamic exercise in dogs. Am J Physiol Heart Circ Physiol 265, H316-H322.
    • (1993) Am J Physiol Heart Circ Physiol , vol.265
    • Sheriff, D.D.1    Zhou, X.P.2    Scher, A.M.3    Rowell, L.B.4
  • 47
    • 73849161656 scopus 로고
    • Force-velocity relations in mammalian heart muscle
    • Sonnenblick EH (1962). Force-velocity relations in mammalian heart muscle. Am J Physiol 202, 931-939.
    • (1962) Am J Physiol , vol.202 , pp. 931-939
    • Sonnenblick, E.H.1
  • 48
    • 2342559242 scopus 로고    scopus 로고
    • Influence of expiratory loading and hyperinflation on cardiac output during exercise
    • Stark-Leyva KN, Beck KC & Johnson BD (2004). Influence of expiratory loading and hyperinflation on cardiac output during exercise. J Appl Physiol 96, 1920-1927.
    • (2004) J Appl Physiol , vol.96 , pp. 1920-1927
    • Stark-Leyva, K.N.1    Beck, K.C.2    Johnson, B.D.3
  • 49
    • 79961041006 scopus 로고    scopus 로고
    • Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise
    • Stöhr EJ, González-Alonso J & Shave R (2011). Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise. Am J Physiol Heart Circ Physiol 301, H478-H487.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Stöhr, E.J.1    González-Alonso, J.2    Shave, R.3
  • 50
    • 0014046403 scopus 로고
    • The effect in humans of increased sympathetic activity on the blood flow to active muscles
    • Strandell T & Shepherd JT (1967). The effect in humans of increased sympathetic activity on the blood flow to active muscles. Acta Med Scand Suppl 472, 146-167.
    • (1967) Acta Med Scand Suppl , vol.472 , pp. 146-167
    • Strandell, T.1    Shepherd, J.T.2
  • 51
    • 0022610887 scopus 로고
    • The effect of pericardiectomy on maximal oxygen consumption and maximal cardiac output in untrained dogs
    • Stray-Gundersen J, Musch TI, Haidet GC, Swain DP, Ordway GA & Mitchell JH (1986). The effect of pericardiectomy on maximal oxygen consumption and maximal cardiac output in untrained dogs. Circ Res 58, 523-530.
    • (1986) Circ Res , vol.58 , pp. 523-530
    • Stray-Gundersen, J.1    Musch, T.I.2    Haidet, G.C.3    Swain, D.P.4    Ordway, G.A.5    Mitchell, J.H.6
  • 52
    • 0026101615 scopus 로고
    • Ventricular external constraint by the lung and pericardium during positive end-expiratory pressure
    • Takata M & Robotham JL (1991). Ventricular external constraint by the lung and pericardium during positive end-expiratory pressure. Am Rev Respir Dis 143, 872-875.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 872-875
    • Takata, M.1    Robotham, J.L.2
  • 53
    • 85047679621 scopus 로고
    • Left ventricular stiffness during diastole and systole: the influence of changes in volume and inotropic state
    • Templeton GH, Ecker RR & Mitchell JH (1972). Left ventricular stiffness during diastole and systole: the influence of changes in volume and inotropic state. Cardiovasc Res 6, 95-100.
    • (1972) Cardiovasc Res , vol.6 , pp. 95-100
    • Templeton, G.H.1    Ecker, R.R.2    Mitchell, J.H.3
  • 54
    • 33750960272 scopus 로고    scopus 로고
    • Assessment of left ventricular function by cardiac ultrasound
    • Thomas JD & Popović ZB (2006). Assessment of left ventricular function by cardiac ultrasound. J Am Coll Cardiol 48, 2012-2025.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2012-2025
    • Thomas, J.D.1    Popović, Z.B.2
  • 55
    • 84856546666 scopus 로고    scopus 로고
    • Attenuated relationship between cardiac output and oxygen uptake during high-intensity exercise
    • Trinity JD, Lee JF, Pahnke MD, Beck KC & Coyle EF (2012). Attenuated relationship between cardiac output and oxygen uptake during high-intensity exercise. Acta Physiol 204, 362-370.
    • (2012) Acta Physiol , vol.204 , pp. 362-370
    • Trinity, J.D.1    Lee, J.F.2    Pahnke, M.D.3    Beck, K.C.4    Coyle, E.F.5
  • 56
    • 0018120744 scopus 로고
    • Evidence of incomplete left ventricular relaxation in the dog: prediction from the time constant for isovolumic pressure fall
    • Weisfeldt ML, Frederiksen JW, Yin FC & Weiss JL (1978). Evidence of incomplete left ventricular relaxation in the dog: prediction from the time constant for isovolumic pressure fall. J Clin Invest 62, 1296-1302.
    • (1978) J Clin Invest , vol.62 , pp. 1296-1302
    • Weisfeldt, M.L.1    Frederiksen, J.W.2    Yin, F.C.3    Weiss, J.L.4


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