Tiotropium sustains the anti-inflammatory action of olodaterol via the cyclic AMP pathway

Pulmonary Pharmacology and Therapeutics

Volumn 27, Issue 1, 2014, Pages 29-37

  Costa, Luigi ^a   Roth, Michael ^a   Miglino, Nicola ^a   Keglowich, Laura ^a   Zhong, Jun ^a   Lardinois, Didier ^a   Tamm, Michael ^a   Borger, Pieter ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Airway biology; Airway pharmacology; Anticholinergics; Asthma therapy; Beta 2 agonists; Fibroblasts

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBACHOL; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; OLODATEROL; PLATELET DERIVED GROWTH FACTOR; TIOTROPIUM BROMIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CELL STIMULATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG FIBROBLAST; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AIRWAY BIOLOGY; AIRWAY PHARMACOLOGY; ANTICHOLINERGICS; ASTHMA THERAPY; BETA-2 AGONISTS; FIBROBLASTS;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ASTHMA; BENZOXAZINES; BRONCHODILATOR AGENTS; CARBACHOL; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; FIBROBLASTS; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MIDDLE AGED; MUSCARINIC ANTAGONISTS; PHOSPHORYLATION; SCOPOLAMINE DERIVATIVES; SIGNAL TRANSDUCTION;

EID: 84892442238     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2013.11.001     Document Type: Article

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