Amelioration of dextran sulphate sodium-induced colitis in mice by echinacoside-enriched extract of cistanche tubulosa

Phytotherapy Research

Volumn 28, Issue 1, 2014, Pages 110-119

  Jia, Yamin ^a,b   Guan, Qiunong ^b   Jiang, Yong ^c   Salh, Baljinder ^d   Guo, Yuhai ^a   Tu, Pengfei ^c   Du, Caigan ^b  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE   (Canada)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

colitis; echinacoside; herba Cistanche; inflammatory bowel disease; TGF beta; tissue repair

Indexed keywords

ECHINACOSIDE; KI 67 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL INFILTRATION; CISTANCHE; CISTANCHE TUBULOSA; COLON INJURY; CONTROLLED STUDY; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DISEASE ACTIVITY; DRUG MECHANISM; HISTOPATHOLOGY; INTESTINE EPITHELIUM; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ULCERATIVE COLITIS; UPREGULATION; WOUND HEALING;

CISTANCHE; CISTANCHE TUBULOSA; MUS;

COLITIS; ECHINACOSIDE; HERBA CISTANCHE; INFLAMMATORY BOWEL DISEASE; TGF-BETA; TISSUE REPAIR;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL PROLIFERATION; CISTANCHE; COLITIS; COLITIS, ULCERATIVE; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; GLYCOSIDES; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED C3H; PLANT EXTRACTS; TRANSFORMING GROWTH FACTOR BETA1; WOUND HEALING;

EID: 84892433928     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4967     Document Type: Article

References (53)

1. Abdelaziz N, Colombo F, Mercier I, Calderone A,. 2001. Nitric oxide attenuates the expression of transforming growth factor-beta3 mRNA in rat cardiac fibroblasts via destabilization. Hypertension 38: 261-266.
2. Aharoni R, Kayhan B, Brenner O, Domev H, Labunskay G, Arnon R,. 2006. Immunomodulatory therapeutic effect of glatiramer acetate on several murine models of inflammatory bowel disease. J Pharmacol Exp Ther 318: 68-78.
3. Baumgart DC, Sandborn WJ,. 2007. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369: 1641-1657.
4. Bernstein CN, Nugent Z, Blanchard JF,. 2011. 5-Aminosalicylate is not chemoprophylactic for colorectal cancer in IBD: a population based study. Am J Gastroenterol 106: 731-736.
5. Bernstein CN, Wajda A, Svenson LW, et al,. 2006. The epidemiology of inflammatory bowel disease in Canada: a population-based study. Am J Gastroenterol 101: 1559-1568.
6. Bruckner M, Westphal S, Domschke W, Kucharzik T, Lugering A,. 2012. Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis. J Crohns Colitis 6: 226-235.
7. Bullwinkel J, Baron-Luhr B, Ludemann A, Wohlenberg C, Gerdes J, Scholzen T,. 2006. Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells. J Cell Physiol 206: 624-635.
8. Cervellati R, Renzulli C, Guerra MC, Speroni E,. 2002. Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. J Agric Food Chem 50: 7504-7509.
9. Chen H, Jing FC, Li CL, Tu PF, Zheng QS, Wang ZH,. 2007. Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats. J Ethnopharmacol 114: 285-289.
10. Dalby-Brown L, Barsett H, Landbo AK, Meyer AS, Molgaard P,. 2005. Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins. J Agric Food Chem 53: 9413-9423.
11. Deng M, Zhao JY, Tu PF, Jiang Y, Li ZB, Wang YH,. 2004. Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis. Eur J Pharmacol 505: 11-18.
12. Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T,. 1999. Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res 59: 3379-3386.
13. Engle SJ, Ormsby I, Pawlowski S, et al,. 2002. Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice. Cancer Res 62: 6362-6366.
14. Facino RM, Carini M, Aldini G, Saibene L, Pietta P, Mauri P,. 1995. Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage. Planta Med 61: 510-514.
15. Geng X, Tian X, Tu P, Pu X,. 2007. Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease. Eur J Pharmacol 564: 66-74.
16. Grisham MB, Everse J, Janssen HF,. 1988. Endotoxemia and neutrophil activation in vivo. Am J Physiol 254: H1017-H1022.
17. Hahm KB, Im YH, Parks TW, et al,. 2001. Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut 49: 190-198.
18. Hausmann M, Obermeier F, Paper DH, et al,. 2007. In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis. Clin Exp Immunol 148: 373-381.
19. He WJ, Fang TH, Ma X, Zhang K, Ma ZZ, Tu PF,. 2009. Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway. Planta Med 75: 1400-1404.
20. Jia Y, Guan Q, Guo Y, Du C,. 2012. Echinacoside stimulates cell proliferation and prevents cell apoptosis in intestinal epithelial MODE-K cells by up-regulation of transforming growth factor-beta1 expression. J Pharmacol Sci 118: 99-108.
21. Jiang Y, Tu PF,. 2009. Analysis of chemical constituents in Cistanche species. J Chromatogr A 1216: 1970-1979.
22. Kalyan Kumar G, Dhamotharan R, Kulkarni NM, Mahat MY, Gunasekaran J, Ashfaque M,. 2011. Embelin reduces cutaneous TNF-alpha level and ameliorates skin edema in acute and chronic model of skin inflammation in mice. Eur J Pharmacol 662: 63-69.
23. Kruidenier L, Van Meeteren ME, Kuiper I, et al,. 2003. Attenuated mild colonic inflammation and improved survival from severe DSS-colitis of transgenic Cu/Zn-SOD mice. Free Radic Biol Med 34: 753-765.
24. 2-induced cytotoxicity in PC12 cells. Planta Med 75: 1499-1504.
25. Kucharzik T, Hudson JT 3rd, Lugering A, et al,. 2005. Acute induction of human IL-8 production by intestinal epithelium triggers neutrophil infiltration without mucosal injury. Gut 54: 1565-1572.
26. Laukoetter MG, Nava P, Lee WY, et al,. 2007. JAM-A regulates permeability and inflammation in the intestine in vivo. J Exp Med 204: 3067-3076.
27. Loftus EV Jr., 2004. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 126: 1504-1517.
28. Mangat BK, Evaschen C, Lee T, Yoshida EM, Salh B,. 2011. Ethnic variation in the annual rates of adult inflammatory bowel disease in hospitalized patients in Vancouver, British Columbia. Can J Gastroenterol 25: 73-77.
29. Matsuura M, Okazaki K, Nishio A, et al,. 2005. Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis. Gastroenterology 128: 975-986.
30. Monteleone G, Boirivant M, Pallone F, Macdonald TT,. 2008. TGF-beta1 and Smad7 in the regulation of IBD. Mucosal Immunol 1 (Suppl 1): S50-S53.
31. Moustakas A, Pardali K, Gaal A, Heldin CH,. 2002. Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation. Immunol Lett 82: 85-91.
32. Owen CR, Yuan L, Basson MD,. 2008. Smad3 knockout mice exhibit impaired intestinal mucosal healing. Lab Invest 88: 1101-1109.
33. Oz HS, Chen TS, Mcclain CJ, De Villiers WJ,. 2005. Antioxidants as novel therapy in a murine model of colitis. J Nutr Biochem 16: 297-304.
34. Ozawa T, Miyata M, Nishimura M, et al,. 2009. Transforming growth factor-beta activity in commercially available pasteurized cow milk provides protection against inflammation in mice. J Nutr 139: 69-75.
35. Pellati F, Benvenuti S, Magro L, Melegari M, Soragni F,. 2004. Analysis of phenolic compounds and radical scavenging activity of Echinacea spp. J Pharm Biomed Anal 35: 289-301.
36. Perry NB, Burgess EJ, Glennie WL,. 2001. Echinacea standardization: analytical methods for phenolic compounds and typical levels in medicinal species. J Agric Food Chem 49: 1702-1706.
37. Rahmanzadeh R, Huttmann G, Gerdes J, Scholzen T,. 2007. Chromophore-assisted light inactivation of PKi-67 leads to inhibition of ribosomal RNA synthesis. Cell Prolif 40: 422-430.
38. Rani R, Smulian AG, Greaves DR, Hogan SP, Herbert DR,. 2011. TGF-beta limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. Eur J Immunol 41: 2000-2009.
39. Sakuraba H, Ishiguro Y, Yamagata K, Munakata A, Nakane A,. 2007. Blockade of TGF-beta accelerates mucosal destruction through epithelial cell apoptosis. Biochem Biophys Res Commun 359: 406-412.
40. Sanchez-Fidalgo S, Cardeno A, Villegas I, Talero E, De La Lastra CA,. 2010. Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice. Eur J Pharmacol 633: 78-84.
41. Satoh Y, Ishiguro Y, Sakuraba H, et al,. 2009. Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling. Am J Physiol Gastrointest Liver Physiol 297: G514-G519.
42. Scholzen T, Gerdes J,. 2000. The Ki-67 protein: from the known and the unknown. J Cell Physiol 182: 311-322.
43. Sloley BD, Urichuk LJ, Tywin C, Coutts RT, Pang PK, Shan JJ,. 2001. Comparison of chemical components and antioxidants capacity of different Echinacea species. J Pharm Pharmacol 53: 849-857.
44. Speroni E, Govoni P, Guizzardi S, Renzulli C, Guerra MC,. 2002. Anti-inflammatory and cicatrizing activity of Echinacea pallida Nutt. root extract. J Ethnopharmacol 79: 265-272.
45. Vidal K, Grosjean I, Evillard JP, Gespach C, Kaiserlian D,. 1993. Immortalization of mouse intestinal epithelial cells by the SV40-large T gene. Phenotypic and immune characterization of the MODE-K cell line. J Immunol Methods 166: 63-73.
46. Wirtz S, Neufert C, Weigmann B, Neurath MF,. 2007. Chemically induced mouse models of intestinal inflammation. Nat Protoc 2: 541-546.
47. Wu Y, Li L, Wen T, Li YQ,. 2007. Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats. Toxicology 232: 50-56.
48. Xie H, Zhu H, Cheng C, Liang Y, Wang Z,. 2009. Echinacoside retards cellular senescence of human fibroblastic cells MRC-5. Pharmazie 64: 752-754.
49. Xie J, Deng J, Tan F, Su J,. 2010. Separation and purification of echinacoside from Penstemon barbatus (Can.) Roth by recycling high-speed counter-current chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 878: 2665-2668.
50. Xiong Q, Kadota S, Tani T, Namba T,. 1996. Antioxidative effects of phenylethanoids from Cistanche deserticola. Biol Pharm Bull 19: 1580-1585.
51. Zhang Y, Xing J, Ai T, Wen T, Guan L, Zhao J,. 2007. Protection of echinacoside against acute lung injury caused by oleic acid in rats. Free Radic Res 41: 798-805.
52. Zhao Q, Gao J, Li W, Cai D,. 2010. Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease. Brain Res 1346: 224-236.
53. Zhu H, Li YR,. 2012. Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence. Exp Biol Med (Maywood) 237: 474-480.