메뉴 건너뛰기




Volumn 1346, Issue , 2010, Pages 224-236

Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease

Author keywords

BDNF; Echinacoside; GDNF; MPTP; Neurorescue; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; DOPAMINE TRANSPORTER; ECHINACOSIDE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NEUROTROPHIC FACTOR; PROTEIN BAX; PROTEIN BCL 2; GLYCOSIDE; NERVE GROWTH FACTOR; TYROSINE 3 MONOOXYGENASE;

EID: 77955514855     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.05.018     Document Type: Article
Times cited : (97)

References (58)
  • 1
    • 67349133927 scopus 로고    scopus 로고
    • Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease
    • L. Andereggen, M. Meyer, R. Guzman, A.D. Ducray, and H.R. Widmer Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease Brain Res. 1276 2009 39 49
    • (2009) Brain Res. , vol.1276 , pp. 39-49
    • Andereggen, L.1    Meyer, M.2    Guzman, R.3    Ducray, A.D.4    Widmer, H.R.5
  • 2
    • 33846501598 scopus 로고    scopus 로고
    • GDNF family receptor complexes are emerging drug targets
    • M.M. Bespalov, and M. Saarma GDNF family receptor complexes are emerging drug targets Trends Pharmacol. Sci. 28 2007 68 74
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 68-74
    • Bespalov, M.M.1    Saarma, M.2
  • 3
    • 0025185581 scopus 로고
    • An assessment of the validity of densitometric measures of striatal tyrosine hydroxylase-positive fibers: Relationship to apomorphine-induced rotations in 6-hydroxydopamine lesioned rats
    • R.E. Burke, J.L. Cadet, J.L. Kent, A.L. Karanas, and V. Jackson-Lewis An assessment of the validity of densitometric measures of striatal tyrosine hydroxylase-positive fibers: relationship to apomorphine-induced rotations in 6-hydroxydopamine lesioned rats J. Neurosci. Meth. 35 1990 63 73
    • (1990) J. Neurosci. Meth. , vol.35 , pp. 63-73
    • Burke, R.E.1    Cadet, J.L.2    Kent, J.L.3    Karanas, A.L.4    Jackson-Lewis, V.5
  • 4
    • 35648956703 scopus 로고    scopus 로고
    • Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats
    • DOI 10.1016/j.jep.2007.07.035, PII S0378874107003698
    • H. Chen, F.C. Jing, C.L. Li, P.F. Tu, Q.S. Zheng, and Z.H. Wang Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats J. Ethnopharmacol. 114 2007 285 289 (Pubitemid 350026211)
    • (2007) Journal of Ethnopharmacology , vol.114 , Issue.3 , pp. 285-289
    • Chen, H.1    Jing, F.C.2    Li, C.L.3    Tu, P.F.4    Zheng, Q.S.5    Wang, Z.H.6
  • 5
    • 34547762666 scopus 로고    scopus 로고
    • Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease
    • L.W. Chen, Y.Q. Wang, L.C. Wei, M. Shi, and Y.S. Chan Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease CNS Neurol. Disord. Drug Targets 6 2007 273 281
    • (2007) CNS Neurol. Disord. Drug Targets , vol.6 , pp. 273-281
    • Chen, L.W.1    Wang, Y.Q.2    Wei, L.C.3    Shi, M.4    Chan, Y.S.5
  • 6
    • 28944434991 scopus 로고    scopus 로고
    • Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins
    • L. Dalby-Brown, H. Barsett, A.K. Landbo, A.S. Meyer, and P. Molgaard Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins J. Agric. Food Chem. 53 2005 9413 9423
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 9413-9423
    • Dalby-Brown, L.1    Barsett, H.2    Landbo, A.K.3    Meyer, A.S.4    Molgaard, P.5
  • 7
    • 8844250790 scopus 로고    scopus 로고
    • Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis
    • M. Deng, J.Y. Zhao, P.F. Tu, Y. Jiang, Z.B. Li, and Y.H. Wang Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis Eur. J. Pharmacol. 28 2004 11 18
    • (2004) Eur. J. Pharmacol. , vol.28 , pp. 11-18
    • Deng, M.1    Zhao, J.Y.2    Tu, P.F.3    Jiang, Y.4    Li, Z.B.5    Wang, Y.H.6
  • 8
    • 33645841626 scopus 로고    scopus 로고
    • Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease
    • G.P. Dietz, P.C. Valbuena, B. Dietz, K. Meuer, P. Mueller, J.H. Weishaupt, and M. Bahr Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease Brain Res. 1082 2006 61 66
    • (2006) Brain Res. , vol.1082 , pp. 61-66
    • Dietz, G.P.1    Valbuena, P.C.2    Dietz, B.3    Meuer, K.4    Mueller, P.5    Weishaupt, J.H.6    Bahr, M.7
  • 9
    • 0037196246 scopus 로고    scopus 로고
    • A simple method to measure stride length as an index of nigrostriatal dysfunction in mice
    • P.O. Fernagut, E. Diguet, B. Labattu, and F. Tison A simple method to measure stride length as an index of nigrostriatal dysfunction in mice J. Neurosci. Methods 113 2002 123 130
    • (2002) J. Neurosci. Methods , vol.113 , pp. 123-130
    • Fernagut, P.O.1    Diguet, E.2    Labattu, B.3    Tison, F.4
  • 11
    • 34250640707 scopus 로고    scopus 로고
    • Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease
    • DOI 10.1016/j.ejphar.2007.01.084, PII S0014299907001197
    • X. Geng, X. Tian, P. Tu, and X. Pu Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease Eur. J. Pharmacol. 564 2007 66 74 (Pubitemid 46946841)
    • (2007) European Journal of Pharmacology , vol.564 , Issue.1-3 , pp. 66-74
    • Geng, X.1    Tian, X.2    Tu, P.3    Pu, X.4
  • 12
    • 65649142603 scopus 로고    scopus 로고
    • Research progress on pharmacological activities of echinacoside
    • W. He, T. Fang, and P. Tu Research progress on pharmacological activities of echinacoside Zhongguo Zhong Yao Za Zhi 34 2009 476 479
    • (2009) Zhongguo Zhong Yao Za Zhi , vol.34 , pp. 476-479
    • He, W.1    Fang, T.2    Tu, P.3
  • 13
    • 44649154416 scopus 로고    scopus 로고
    • Neurotoxicity of MPTP to migrating neuroblasts: Studies in acute and subacute mouse models of Parkinson's disease
    • X.J. He, H. Yamauchi, K. Uetsuka, and H. Nakayama Neurotoxicity of MPTP to migrating neuroblasts: studies in acute and subacute mouse models of Parkinson's disease Neurotoxicology 29 2008 413 420
    • (2008) Neurotoxicology , vol.29 , pp. 413-420
    • He, X.J.1    Yamauchi, H.2    Uetsuka, K.3    Nakayama, H.4
  • 15
    • 34347259269 scopus 로고    scopus 로고
    • Protocol for the MPTP mouse model of Parkinson's disease
    • V. Jackson-Lewis, and S. Przedborski Protocol for the MPTP mouse model of Parkinson's disease Nat. Protoc. 2 2007 141 151
    • (2007) Nat. Protoc. , vol.2 , pp. 141-151
    • Jackson-Lewis, V.1    Przedborski, S.2
  • 16
    • 41949130335 scopus 로고    scopus 로고
    • Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice
    • X.Y. Kong, Z. Cai, L. Pan, L. Zhang, J. Shu, Y.L. Dong, N. Yang, Q. Li, X.J. Huang, and P.P. Zuo Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice Brain Res. 1205 2008 108 115
    • (2008) Brain Res. , vol.1205 , pp. 108-115
    • Kong, X.Y.1    Cai, Z.2    Pan, L.3    Zhang, L.4    Shu, J.5    Dong, Y.L.6    Yang, N.7    Li, Q.8    Huang, X.J.9    Zuo, P.P.10
  • 17
    • 73349133982 scopus 로고    scopus 로고
    • Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells
    • R. Kuang, Y. Sun, W. Yuan, L. Lei, and X. Zheng Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells Planta Med. 75 2009 1499 1504
    • (2009) Planta Med. , vol.75 , pp. 1499-1504
    • Kuang, R.1    Sun, Y.2    Yuan, W.3    Lei, L.4    Zheng, X.5
  • 19
    • 33947357645 scopus 로고    scopus 로고
    • Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells
    • K. Hisaoka, M. Takebayashi, M. Tsuchioka, N. Maeda, Y. Nakata, and S. Yamawaki Antidepressants increase glial cell line-derived neurotrophic factor production through monoamine independent activation of protein tyrosine kinase and extracellular signal-regulated kinase in glial cells J. Pharmacol. Exp. Ther. 321 2007 148 157
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 148-157
    • Hisaoka, K.1    Takebayashi, M.2    Tsuchioka, M.3    Maeda, N.4    Nakata, Y.5    Yamawaki, S.6
  • 20
    • 67349284641 scopus 로고    scopus 로고
    • Lipopolysaccharide mitagates methamphetamine-induced striatal dopamine depletion via modulating local TNF-α and dopamine transporter expression
    • Y.T. Lai, Y.P. Tsai, C.G. Cherng, J.J. Ke, M.C. Ho, C.W. Tsai, and L. Yu Lipopolysaccharide mitagates methamphetamine-induced striatal dopamine depletion via modulating local TNF-α and dopamine transporter expression J. Neural. Transm. 116 2009 405 415
    • (2009) J. Neural. Transm. , vol.116 , pp. 405-415
    • Lai, Y.T.1    Tsai, Y.P.2    Cherng, C.G.3    Ke, J.J.4    Ho, M.C.5    Tsai, C.W.6    Yu, L.7
  • 21
    • 62449129138 scopus 로고    scopus 로고
    • Cell death pathways in Parkinson's disease: Proximal triggers, distal effectors, and final steps
    • O.A. Levy, C. Malagelada, and L.A. Greene Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps Apoptosis 14 2009 478 500
    • (2009) Apoptosis , vol.14 , pp. 478-500
    • Levy, O.A.1    Malagelada, C.2    Greene, L.A.3
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 33644848964 scopus 로고    scopus 로고
    • Involvement of neurotrophic factors in aging of noradrenergic innervations in hippocampus and frontal cortex
    • W. Matsunaga, K. Isobe, and T. Shirokawa Involvement of neurotrophic factors in aging of noradrenergic innervations in hippocampus and frontal cortex Neurosci. Res. 54 2006 313 318
    • (2006) Neurosci. Res. , vol.54 , pp. 313-318
    • Matsunaga, W.1    Isobe, K.2    Shirokawa, T.3
  • 24
    • 33748300291 scopus 로고    scopus 로고
    • Behavioral models of Parkinson's disease in rodents: A new look at an old problem
    • G.E. Meredith, and U.J. Kang Behavioral models of Parkinson's disease in rodents: a new look at an old problem Mov. Disord. 21 2006 1595 1606
    • (2006) Mov. Disord. , vol.21 , pp. 1595-1606
    • Meredith, G.E.1    Kang, U.J.2
  • 25
    • 64849110996 scopus 로고    scopus 로고
    • Current status of gene therapy for Parkinson disease
    • H. Mochizuki Current status of gene therapy for Parkinson disease Brain Nerve 61 2009 485 493
    • (2009) Brain Nerve , vol.61 , pp. 485-493
    • Mochizuki, H.1
  • 26
    • 34347403884 scopus 로고    scopus 로고
    • Convective delivery of glial cell line-derived neurotrophic factor in the human putamen
    • P.F. Morrison, R.R. Lonser, and E.H. Oldfield Convective delivery of glial cell line-derived neurotrophic factor in the human putamen J. Neurosurg. 107 2007 74 83
    • (2007) J. Neurosurg. , vol.107 , pp. 74-83
    • Morrison, P.F.1    Lonser, R.R.2    Oldfield, E.H.3
  • 27
    • 33646338882 scopus 로고    scopus 로고
    • Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine/probenecid model of Parkinson's disease
    • L. Novikova, B.L. Garris, D.R. Garris, and Y.S. Lau Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease Neuroscience 19 2006 67 76
    • (2006) Neuroscience , vol.19 , pp. 67-76
    • Novikova, L.1    Garris, B.L.2    Garris, D.R.3    Lau, Y.S.4
  • 29
    • 0037096359 scopus 로고    scopus 로고
    • Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration
    • S. Palfi, L. Leventhal, Y. Chu, S.Y. Ma, M. Emborg, R. Bakay, N. Deglon, P. Hantraye, P. Aebischer, and J.H. Kordower Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration J. Neurosci. 22 2002 4942 4954
    • (2002) J. Neurosci. , vol.22 , pp. 4942-4954
    • Palfi, S.1    Leventhal, L.2    Chu, Y.3    Ma, S.Y.4    Emborg, M.5    Bakay, R.6    Deglon, N.7    Hantraye, P.8    Aebischer, P.9    Kordower, J.H.10
  • 31
    • 41249088472 scopus 로고    scopus 로고
    • Treatment of Parkinson's disease with trophic factors
    • A.L. Peterson, and J.G. Nutt Treatment of Parkinson's disease with trophic factors Neurotherapeutics 5 2008 270 280
    • (2008) Neurotherapeutics , vol.5 , pp. 270-280
    • Peterson, A.L.1    Nutt, J.G.2
  • 32
    • 0035960066 scopus 로고    scopus 로고
    • Mouse model of Parkinsonism: A comparison between subacute MPTP and chronic MPTP/probenecid treatment
    • E. Petroske, G.E. Meredith, S. Callen, S. Totterdell, and Y.S. Lau Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment Neuroscience 106 2001 589 601
    • (2001) Neuroscience , vol.106 , pp. 589-601
    • Petroske, E.1    Meredith, G.E.2    Callen, S.3    Totterdell, S.4    Lau, Y.S.5
  • 33
    • 55049090172 scopus 로고    scopus 로고
    • Driving GDNF expression: The green and the red traffic lights
    • A. Saavedra, G. Baltazar, and E.P. Duarte Driving GDNF expression: the green and the red traffic lights Prog. Neurobiol. 86 2008 186 215
    • (2008) Prog. Neurobiol. , vol.86 , pp. 186-215
    • Saavedra, A.1    Baltazar, G.2    Duarte, E.P.3
  • 34
    • 33751078859 scopus 로고    scopus 로고
    • Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism
    • DOI 10.1016/j.nbd.2006.07.020, PII S0969996106002063
    • Y. Sagi, S. Mandel, T. Amit, and M.B. Youdim Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism Neurobiol. Dis. 25 2007 35 44 (Pubitemid 44765215)
    • (2007) Neurobiology of Disease , vol.25 , Issue.1 , pp. 35-44
    • Sagi, Y.1    Mandel, S.2    Amit, T.3    Youdim, M.B.H.4
  • 35
    • 33746099710 scopus 로고    scopus 로고
    • The synthetic ceramide analog L-PDMP partially protects striatal dopamine levels but does not promote dopamine neuron survival in murine models of parkinsonism
    • J.S. Schneider, K.A. Bradbury, Y. Anada, J. Inokuchi, and D.W. Anderson The synthetic ceramide analog L-PDMP partially protects striatal dopamine levels but does not promote dopamine neuron survival in murine models of parkinsonism Brain Res. 12 2006 199 205
    • (2006) Brain Res. , vol.12 , pp. 199-205
    • Schneider, J.S.1    Bradbury, K.A.2    Anada, Y.3    Inokuchi, J.4    Anderson, D.W.5
  • 36
    • 34047220707 scopus 로고    scopus 로고
    • Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: Response to 1 year of treatment and 1 year of withdrawal
    • J.T. Slevin, D.M. Gash, C.D. Smith, G.A. Gerhardt, R. Kryscio, H. Chebrolu, A. Walton, R. Wagner, and A.B. Young Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal J. Neurosurg. 106 2007 614 620
    • (2007) J. Neurosurg. , vol.106 , pp. 614-620
    • Slevin, J.T.1    Gash, D.M.2    Smith, C.D.3    Gerhardt, G.A.4    Kryscio, R.5    Chebrolu, H.6    Walton, A.7    Wagner, R.8    Young, A.B.9
  • 38
    • 3042739759 scopus 로고    scopus 로고
    • Molecular basis of anti-apoptotic effect of immunophilin ligands on hydrogen peroxide-induced apoptosis in human glioma cells
    • K. Tanaka, M. Asanuma, and N. Ogawa Molecular basis of anti-apoptotic effect of immunophilin ligands on hydrogen peroxide-induced apoptosis in human glioma cells Neurochem. Res. 29 2004 1529 1536
    • (2004) Neurochem. Res. , vol.29 , pp. 1529-1536
    • Tanaka, K.1    Asanuma, M.2    Ogawa, N.3
  • 39
    • 0030888286 scopus 로고    scopus 로고
    • In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
    • N.A. Tatton, and S.J. Kish In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining Neuroscience 77 1997 1037 1048
    • (1997) Neuroscience , vol.77 , pp. 1037-1048
    • Tatton, N.A.1    Kish, S.J.2
  • 40
    • 0036447089 scopus 로고    scopus 로고
    • Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine
    • J.L. Tillerson, W.M. Caudle, M.E. Reveron, and G.W. Miller Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Exp. Neurol. 178 2002 80 90
    • (2002) Exp. Neurol. , vol.178 , pp. 80-90
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 43
    • 0036708174 scopus 로고    scopus 로고
    • Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: Involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways
    • G. Toth, H. Yang, R.A. Anguelov, J. Vettraino, Y. Wang, and G. Acsadi Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways J. Neurosci. Res. 69 2002 622 632
    • (2002) J. Neurosci. Res. , vol.69 , pp. 622-632
    • Toth, G.1    Yang, H.2    Anguelov, R.A.3    Vettraino, J.4    Wang, Y.5    Acsadi, G.6
  • 44
    • 46749109164 scopus 로고    scopus 로고
    • PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP + in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease
    • N.P. Visanji, A. Orsi, T.H. Johnston, P.A. Howson, K. Dixon, N. Callizot, J.M. Brotchie, and D.D. Rees PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP + in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease FASEB J. 22 2008 2488 2497
    • (2008) FASEB J. , vol.22 , pp. 2488-2497
    • Visanji, N.P.1    Orsi, A.2    Johnston, T.H.3    Howson, P.A.4    Dixon, K.5    Callizot, N.6    Brotchie, J.M.7    Rees, D.D.8
  • 45
    • 34447633219 scopus 로고    scopus 로고
    • Protecting effect of Cistanche extracts on MPP +-induced injury of the Parkinson's disease cell model
    • H. Wang, W.W. Li, D.F. Cai, and R. Yang Protecting effect of Cistanche extracts on MPP +-induced injury of the Parkinson's disease cell model Zhong Xi Yi Jie He Xue Bao 5 2007 407 411
    • (2007) Zhong Xi Yi Jie He Xue Bao , vol.5 , pp. 407-411
    • Wang, H.1    Li, W.W.2    Cai, D.F.3    Yang, R.4
  • 46
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson disease
    • D.C. Wu, V. Jackson-Lewis, M. Vila, K. Tieu, P. Teismann, C. Vadseth, D.K. Choi, H. Ischiropoulos, and S. Przedborski Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson disease J. Neurosci. 22 2002 1763 1771
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 47
    • 33847100476 scopus 로고    scopus 로고
    • Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats
    • Y. Wu, L. Li, T. Wen, and Y.Q. Li Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats Toxicology 232 2007 50 56
    • (2007) Toxicology , vol.232 , pp. 50-56
    • Wu, Y.1    Li, L.2    Wen, T.3    Li, Y.Q.4
  • 48
    • 0036679207 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor up-regulates the expression of tyrosine hydroxylase gene in human neuroblastoma cell lines
    • H. Xiao, Y. Hirata, K. Isobe, and K. Kiuchi Glial cell line-derived neurotrophic factor up-regulates the expression of tyrosine hydroxylase gene in human neuroblastoma cell lines J. Neurochem. 82 2002 801 808
    • (2002) J. Neurochem. , vol.82 , pp. 801-808
    • Xiao, H.1    Hirata, Y.2    Isobe, K.3    Kiuchi, K.4
  • 49
    • 0031976872 scopus 로고    scopus 로고
    • Hepatoprotective activity of phenylethanoids from Cistanche deserticola
    • Q. Xiong, K. Hase, Y. Tezuka, T. Tani, T. Namba, and S. Kadota Hepatoprotective activity of phenylethanoids from Cistanche deserticola Planta Med. 64 1998 120 125
    • (1998) Planta Med. , vol.64 , pp. 120-125
    • Xiong, Q.1    Hase, K.2    Tezuka, Y.3    Tani, T.4    Namba, T.5    Kadota, S.6
  • 51
    • 77950368837 scopus 로고    scopus 로고
    • Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum
    • G. Xu, Z. Xiong, Y. Yong, Z. Wang, Z. Ke, Z. Xia, and Y. Hu Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum Neuroscience 167 2010 174 184
    • (2010) Neuroscience , vol.167 , pp. 174-184
    • Xu, G.1    Xiong, Z.2    Yong, Y.3    Wang, Z.4    Ke, Z.5    Xia, Z.6    Hu, Y.7
  • 52
    • 44949242548 scopus 로고    scopus 로고
    • Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice
    • H. Yokoyama, S. Takagi, Y. Watanabe, H. Kato, and T. Araki Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice J. Neural Transm. 115 2008 831 842
    • (2008) J. Neural Transm. , vol.115 , pp. 831-842
    • Yokoyama, H.1    Takagi, S.2    Watanabe, Y.3    Kato, H.4    Araki, T.5
  • 53
    • 33744942908 scopus 로고    scopus 로고
    • Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently
    • H. Yu, K. Oh-Hashi, T. Tanaka, A. Sai, M. Inoue, Y. Hirata, and K. Kiuchi Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently Pharmacol. Res. 54 2006 39 45
    • (2006) Pharmacol. Res. , vol.54 , pp. 39-45
    • Yu, H.1    Oh-Hashi, K.2    Tanaka, T.3    Sai, A.4    Inoue, M.5    Hirata, Y.6    Kiuchi, K.7
  • 54
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • J. Yuan, and B.A. Yankner Apoptosis in the nervous system Nature 407 2000 802 809
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 55
    • 34347256412 scopus 로고    scopus 로고
    • Protection of echinacoside against acute lung injury caused by oleic acid in rats
    • Y. Zhang, J. Xing, T. Ai, T. Wen, L. Guan, and J. Zhao Protection of echinacoside against acute lung injury caused by oleic acid in rats Free Radic. Res. 41 2007 798 805
    • (2007) Free Radic. Res. , vol.41 , pp. 798-805
    • Zhang, Y.1    Xing, J.2    Ai, T.3    Wen, T.4    Guan, L.5    Zhao, J.6
  • 56
    • 0028827643 scopus 로고
    • Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: A potential use of Echinacea extracts in the prevention of skin photodamage
    • R.M. Facino, M. Carini, G. Aldini, L. Saibene, P. Pietta, and P. Mauri Echinacoside and caffeoyl conjugates protect collagen from free radical-induced degradation: a potential use of Echinacea extracts in the prevention of skin photodamage Planta Med. 61 1995 510 514
    • (1995) Planta Med. , vol.61 , pp. 510-514
    • Facino, R.M.1    Carini, M.2    Aldini, G.3    Saibene, L.4    Pietta, P.5    Mauri, P.6
  • 58
    • 0025327731 scopus 로고
    • Unbiased stereological estimation of the number of neurons in the human hippocampus
    • M.J. West, and H.J. Gundersen Unbiased stereological estimation of the number of neurons in the human hippocampus J. Comp. Neurol. 296 1990 1 22
    • (1990) J. Comp. Neurol. , vol.296 , pp. 1-22
    • West, M.J.1    Gundersen, H.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.