-
1
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky, D. K. Inflammatory bowel disease. N. Engl. J. Med. 347, 417-429 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
2
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
Bouma, G. & Strober, W. The immunological and genetic basis of inflammatory bowel disease. Nat. Rev. Immunol. 3, 521-533 (2003).
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
3
-
-
0027724228
-
Transforming growth factor-β1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease
-
Kulkarni, A. B. & Karlsson, S. Transforming growth factor-β1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease. Am. J. Pathol. 143, 3-9 (1993).
-
(1993)
Am. J. Pathol
, vol.143
, pp. 3-9
-
-
Kulkarni, A.B.1
Karlsson, S.2
-
4
-
-
0036372440
-
Transforming growth factor-β in T-cell biology
-
Goreli, L. & Flavell, R. A. Transforming growth factor-β in T-cell biology. Nat. Rev. Immunol. 2, 46-53 (2002).
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 46-53
-
-
Goreli, L.1
Flavell, R.A.2
-
5
-
-
0029995799
-
Experimental granulomatous colitis in mice is abrogated by induction of TGF-β---mediated oral tolerance
-
Neurath, M. F. et al. Experimental granulomatous colitis in mice is abrogated by induction of TGF-β---mediated oral tolerance. J. Exp. Med. 183, 2605-2616 (1996).
-
(1996)
J. Exp. Med
, vol.183
, pp. 2605-2616
-
-
Neurath, M.F.1
-
6
-
-
0032538915
-
Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4
-
Boirivant, M., Fuss, I. J., Chu, A. & Strober, W. Oxazolone colitis: a murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J. Exp. Med. 188, 1929-1939 (1998).
-
(1998)
J. Exp. Med
, vol.188
, pp. 1929-1939
-
-
Boirivant, M.1
Fuss, I.J.2
Chu, A.3
Strober, W.4
-
7
-
-
0029956024
-
A critical role for transforming growth factor-β but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RBlow CD4+ T cells
-
Powrie, F., Carlino, J., Leach, M. W., Mauze, S. & Coffman, R. L. A critical role for transforming growth factor-β but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RBlow CD4+ T cells. J. Exp. Med. 183, 2669-2674 (1996).
-
(1996)
J. Exp. Med
, vol.183
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
8
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C.-H., Kohei, M. & ten Dijke, P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471 (1997).
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Kohei, M.2
Ten Dijke, P.3
-
9
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T-cell responsiveness to TGF-β
-
Yang, X. et al. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T-cell responsiveness to TGF-β. EMBO J. 18, 1280-1291 (1999).
-
(1999)
EMBO J
, vol.18
, pp. 1280-1291
-
-
Yang, X.1
-
10
-
-
42549143615
-
Blockade of transforming growth factor-β upregulates T-box transcription factor T-bet, and increases T-helper-cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa
-
Di Sabatino, A. et al. Blockade of transforming growth factor-β upregulates T-box transcription factor T-bet, and increases T-helper-cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa. Gut 57, 605-612 (2008).
-
(2008)
Gut
, vol.57
, pp. 605-612
-
-
Di Sabatino, A.1
-
11
-
-
0034894059
-
Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease
-
Monteleone, G. et al. Blocking Smad7 restores TGF-β1 signaling in chronic inflammatory bowel disease. J. Clin. Invest. 108, 601-609 (2001).
-
(2001)
J. Clin. Invest
, vol.108
, pp. 601-609
-
-
Monteleone, G.1
-
12
-
-
0029913624
-
Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease
-
Babyatsky, M. W., Rossiter, G. & Podolsky, D. K. Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease. Gastroenterology 110, 975-984 (1996).
-
(1996)
Gastroenterology
, vol.110
, pp. 975-984
-
-
Babyatsky, M.W.1
Rossiter, G.2
Podolsky, D.K.3
-
13
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling
-
Nakao, A. et al. Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling. Nature 389, 631-635 (1997).
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
-
14
-
-
1042266673
-
A failure of transforming growth factor-β 1 negative regulation maintains sustained NF-κB activation in gut inflammation
-
Monteleone, G. et al. A failure of transforming growth factor-β 1 negative regulation maintains sustained NF-κB activation in gut inflammation. J. Biol. Chem. 279, 3925-3932 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 3925-3932
-
-
Monteleone, G.1
-
15
-
-
10744231157
-
Induction and regulation of Smad7 in the gastric mucosa of patients with Helicobacter pylori infection
-
Monteleone, G. et al. Induction and regulation of Smad7 in the gastric mucosa of patients with Helicobacter pylori infection. Gastroenterology 126, 674-682 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 674-682
-
-
Monteleone, G.1
-
16
-
-
33947322862
-
Inhibition of TGF-β signaling by IL-15, a new role for IL-15 in the loss of immune homeostasis in celiac disease
-
Benahmed, M. et al. Inhibition of TGF-β signaling by IL-15, a new role for IL-15 in the loss of immune homeostasis in celiac disease. Gastroenterology 132, 994-1008 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 994-1008
-
-
Benahmed, M.1
-
17
-
-
19344374130
-
Smad7 in TGF-β-mediated negative regulation of gut inflammation
-
Monteleone, G., Pallone, F. & MacDonald, T. T. Smad7 in TGF-β-mediated negative regulation of gut inflammation. Trends Immunol. 25, 513-517 (2004).
-
(2004)
Trends Immunol
, vol.25
, pp. 513-517
-
-
Monteleone, G.1
Pallone, F.2
MacDonald, T.T.3
-
18
-
-
27744485015
-
Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease
-
Monteleone, G. et al. Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease. Gastroenterology 129, 1420-1429 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 1420-1429
-
-
Monteleone, G.1
-
19
-
-
33845647693
-
Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-β1-mediated suppression of colitis
-
Boirivant, M. et al. Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-β1-mediated suppression of colitis. Gastroenterology 131, 1786-1798 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 1786-1798
-
-
Boirivant, M.1
|