Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum- stress-mediated intestinal mucosal injury and inflammation in zebrafish

DMM Disease Models and Mechanisms

Volumn 7, Issue 1, 2014, Pages 93-106

  Thakur, Prakash C ^a   Davison, Jon M ^b   Stuckenholz, Carsten ^a   Lu, Lili ^a   Bahary, Nathan ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cdipt; IBD; Phosphoinositides; UPR

Indexed keywords

CHAPERONE; CYTIDINE DIPHOSPHATE DIACYLGLYCEROL INOSITOL 3 PHOSPHATIDYLTRANSFERASE; X BOX BINDING PROTEIN 1;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTERIAL OVERGROWTH; CDIPT GENE; CELL DEATH; CELL INFILTRATION; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOPATHOLOGY; ENDOPLASMIC RETICULUM STRESS; ENTERITIS; GENE; GENE EXPRESSION PROFILING; GOBLET CELL; GOLGI COMPLEX; INFLAMMATORY BOWEL DISEASE; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; INTESTINE VILLUS; INTESTINE VILLUS ATROPHY; MACROAUTOPHAGY; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; SIGNAL TRANSDUCTION; ZEBRA FISH;

CDIPT; IBD; PHOSPHOINOSITIDES; UPR;

ALLELES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; GENOTYPE; GLYCOSYLATION; HUMANS; INFLAMMATION; INTESTINAL MUCOSA; INTESTINES; LEUKOCYTES; MITOCHONDRIA; MUTATION; PHENOTYPE; PHOSPHATIDYLINOSITOLS; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84892426885     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.012864     Document Type: Article

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