Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish

Hepatology

Volumn 54, Issue 2, 2011, Pages 452-462

  Thakur, Prakash C ^a   Stuckenholz, Carsten ^a   Rivera, Marcus R ^b   Davison, Jon M ^a   Yao, Jeffrey K ^c   Amsterdam, Adam ^d   Sadler, Kirsten C ^e   Bahary, Nathan ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALR PROTEIN; CYTIDINE DIPHOSPHATE DIACYLGLYCEROL INOSITOL 3 PHOSPHATIDYLTRANSFERASE; HSPA5 PROTEIN; PHOSPHATIDYLINOSITOL; PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; FERTILIZATION; GENE DISRUPTION; GENE EXPRESSION; GENE ISOLATION; GENE LIBRARY; HEPATOMEGALY; LIVER CELL; LIVER DEVELOPMENT; MICROARRAY ANALYSIS; MUTANT; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; UPREGULATION; ZEBRA FISH;

ANIMALS; CDP-DIACYLGLYCEROL-INOSITOL 3-PHOSPHATIDYLTRANSFERASE; ENDOPLASMIC RETICULUM; FATTY LIVER; HEPATOCYTES; MEMBRANE PROTEINS; MUTATION; PHOSPHATIDYLINOSITOLS; STRESS, PHYSIOLOGICAL; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79960739850     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24349     Document Type: Article

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