A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes

Developmental Cell

Volumn 21, Issue 5, 2011, Pages 813-824

  Kim, Yeun Ju ^a   Guzman Hernandez, Maria Luisa ^a   Balla, Tamas ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DIPHOSPHATE DIACYLGLYCEROL INOSITOL 3 PHOSPHATIDYLTRANSFERASE; DIACYLGLYCEROL; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL;

ARTICLE; CELL MEMBRANE; CELL ORGANELLE; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE; ENDOPLASMIC RETICULUM; HEK293 CELLS; HUMANS; ORGANELLES; PHOSPHATIDYLINOSITOLS; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS);

EID: 80755129133     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2011.09.005     Document Type: Article

References (48)

1. Acharya J.K., Labarca P., Delgado R., Jalink K., Zuker C.S. Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants. Neuron 1998, 20:1219-1229.
2. Agranoff B.W., Bradley R.M., Brady R.O. The enzymatic synthesis of inositol phosphatide. J. Biol. Chem. 1958, 233:1077-1083.
3. Balla T., Varnai P. Visualization of cellular phosphoinositide pools with GFP-fused protein-domains. Curr. Protoc. Cell Biol. 2009, Chapter 24. Unit 24.4.
4. Balla T., Baukal A.J., Guillemette G., Catt K.J. Multiple pathways of inositol polyphosphate metabolism in angiotensin-stimulated adrenal glomerulosa cells. J. Biol. Chem. 1988, 263:4083-4091.
5. Balla T., Szentpetery Z., Kim Y.J. Phosphoinositide signaling: new tools and insights. Physiology (Bethesda) 2009, 24:231-244.
6. Bannam T., Goldfine H. Mutagenesis of active-site histidines of Listeria monocytogenes phosphatidylinositol-specific phospholipase C: effects on enzyme activity and biological function. Infect. Immun. 1999, 67:182-186.
7. Batty I.H., Downes C.P. The inhibition of phosphoinositide synthesis and muscarinic-receptor-mediated phospholipase C activity by Li+ as secondary, selective, consequences of inositol depletion in 1321N1 cells. Biochem. J. 1994, 297:529-537.
8. Carman G.M., Fischl A.S. Phosphatidylinositol synthase from yeast. Methods Enzymol. 1992, 209:305-312.
9. Cockcroft S., Carvou N. Biochemical and biological functions of class I phosphatidylinositol transfer proteins. Biochim. Biophys. Acta 2007, 1771:677-691.
10. Cockcroft S., Garner K. Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?. Crit. Rev. Biochem. Mol. Biol. 2011, 46:89-117.
11. De Camilli P., Meldolesi J. Subcellular distribution of the PI effect in the pancreas of the guinea pig. Life Sci. 1974, 15:711-721.
12. Donaldson J.G., Jackson C.L. ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat. Rev. Mol. Cell Biol. 2011, 12:362-375.
13. Downes C.P., Gray A., Lucocq J.M. Probing phosphoinositide functions in signaling and membrane trafficking. Trends Cell Biol. 2005, 15:259-268.
14. Dries D.R., Gallegos L.L., Newton A.C. A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production. J. Biol. Chem. 2007, 282:826-830.
15. Gillooly D.J., Morrow I.C., Lindsay M., Gould R., Bryant N.J., Gaullier J.M., Parton R.G., Stenmark H. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 2000, 19:4577-4588.
16. Griffith O.H., Ryan M. Bacterial phosphatidylinositol-specific phospholipase C: structure, function, and interaction with lipids. Biochim. Biophys. Acta 1999, 1441:237-254.
17. Halet G. Imaging phosphoinositide dynamics using GFP-tagged protein domains. Biol. Cell 2005, 97:501-518.
18. Halford S., Dulai K.S., Daw S.C., Fitzgibbon J., Hunt D.M. Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes. Genomics 1998, 54:140-144.
19. Hammond G.R., Schiavo G., Irvine R.F. Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). Biochem. J. 2009, 422:23-35.
20. Heacock A.M., Uhler M.D., Agranoff B.W. Cloning of CDP-diacylglycerol synthase from a human neuronal cell line. J. Neurochem. 1996, 67:2200-2203.
21. Hokin L.E., Hokin M.R. Effects of acetylcholine on the turnover of phosphoryl units in individual phospholipids of pancreas slices and brain cortex slices. Biochim. Biophys. Acta 1955, 18:102-110.
22. Hokin L.E., Hokin M.R. The incorporation of 32P from[32P]ATp into polyphosphoinositides and phosphatidic acid in erythrocyte membranes. Biochim. Biophys. Acta 1964, 84:563-575.
23. Ile K.E., Schaaf G., Bankaitis V.A. Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid signaling. Nat. Chem. Biol. 2006, 2:576-583.
24. Imai A., Gershengorn M.C. Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum. Nature 1987, 325:726-728.
25. Inoue T., Heo W.D., Grimley J.S., Wandless T.J., Meyer T. An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways. Nat. Methods 2005, 2:415-418.
26. Jenkinson S., Nahorski S.R., Challiss R.A. Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant m1 muscarinic receptors. Mol. Pharmacol. 1994, 46:1138-1148.
27. Kumano Y., Nikawa J. Functional analysis of mutations in the PIS gene, which encodes Saccharomyces cerevisiae phosphatidylinositol synthase. FEMS Microbiol. Lett. 1995, 126:81-84.
28. Lapetina E.G., Michell R.H. Stimulation by acetylcholine of phosphatidylinositol labelling. Subcellular distribution in rat cerebral-cortex slices. Biochem. J. 1972, 126:1141-1147.
29. Lewis R.S. The molecular choreography of a store-operated calcium channel. Nature 2007, 446:284-287.
30. Lykidis A., Jackson P.D., Rock C.O., Jackowski S. The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content. J. Biol. Chem. 1997, 272:33402-33409.
31. Ma L., Bindokas V.P., Kuznetsov A., Rhodes C., Hays L., Edwardson J.M., Ueda K., Steiner D.F., Philipson L.H. Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc. Natl. Acad. Sci. USA 2004, 101:9266-9271.
32. Michell R.H. Inositol phospholipids and cell surface receptor function. Biochim. Biophys. Acta 1975, 415. 81-47.
33. Michell R.H., Harwood J.L., Coleman R., Hawthorne J.N. Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane. Biochim. Biophys. Acta 1967, 144:649-658.
34. Monaco M.E., Cassai N.D., Sidhu G.S. Subcellular localization of phosphatidylinositol synthesis. Biochem. Biophys. Res. Commun. 2006, 348:1200-1204.
35. Murphy T.R., Vihtelic T.S., Ile K.E., Watson C.T., Willer G.B., Gregg R.G., Bankaitis V.A., Hyde D.R. Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye. Exp. Eye Res. 2011, Published online June 23, 2011. 10.1016/j.exer.2011.06.010.
36. Nakanishi S., Catt K.J., Balla T. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc. Natl. Acad. Sci. USA 1995, 92:5317-5321.
37. Nikawa J., Yamashita S. Yeast mutant defective in synthesis of phosphatidylinositol. Isolation and characterization of a CDPdiacylglycerol-inositol 3-phosphatidyltransferase Km mutant. Eur. J. Biochem. 1982, 125:445-451.
38. Nikawa J., Yamashita S. Phosphatidylinositol synthase from yeast. Biochim. Biophys. Acta 1997, 1348:173-178.
39. Oancea E., Teruel M.N., Quest A.F.G., Meyer T. Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells. J. Cell Biol. 1998, 140:485-498.
40. Patterson G.H., Lippincott-Schwartz J. A photoactivatable GFP for selective photolabeling of proteins and cells. Science 2002, 297:1873-1877.
41. Sasaki T., Takasuga S., Sasaki J., Kofuji S., Eguchi S., Yamazaki M., Suzuki A. Mammalian phosphoinositide kinases and phosphatases. Prog. Lipid Res. 2009, 48:307-343.
42. Sillence D.J., Downes C.P. Subcellular distribution of agonist-stimulated phosphatidylinositol synthesis in 1321 N1 astrocytoma cells. Biochem. J. 1993, 290:381-387.
43. Stefan C.J., Manford A.G., Baird D., Yamada-Hanff J., Mao Y., Emr S.D. Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites. Cell 2011, 144:389-401.
44. Tanaka S., Nikawa J., Imai H., Yamashita S., Hosaka K. Molecular cloning of rat phosphatidylinositol synthase cDNA by functional complementation of the yeast Saccharomyces cerevisiae pis mutation. FEBS Lett. 1996, 393:89-92.
45. Thakur P.C., Stuckenholz C., Rivera M.R., Davison J.M., Yao J.K., Amsterdam A., Sadler K.C., Bahary N. Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish. Hepatology 2011, 54:452-462.
46. Várnai P., Tóth B., Tóth D.J., Hunyady L., Balla T. Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex. J. Biol. Chem. 2007, 282:29678-29690.
47. Wei Z., Zenewicz L.A., Goldfine H. Listeria monocytogenes phosphatidylinositol-specific phospholipase C has evolved for virulence by greatly reduced activity on GPI anchors. Proc. Natl. Acad. Sci. USA 2005, 102:12927-12931.
48. Wu L., Niemeyer B., Colley N., Socolich M., Zuker C.S. Regulation of PLC-mediated signalling in vivo by CDP-diacylglycerol synthase. Nature 1995, 373:216-222.