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Volumn 232, Issue 3, 2014, Pages 308-318

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis

Author keywords

EZH2; KPNB1; miR 30d; MPNST; tumourigenesis

Indexed keywords

KARYOPHERIN BETA; KARYOPHERIN BETA 1; MICRORNA; MICRORNA 30D; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

EID: 84892379559     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4294     Document Type: Article
Times cited : (56)

References (28)
  • 1
    • 77951761066 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumour (MPNST): The clinical implications of cellular signalling pathways
    • Katz D, Lazar A, Lev D,. Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways. Expert Rev Mol Med 2009; 11: e30.
    • (2009) Expert Rev Mol Med , vol.11
    • Katz, D.1    Lazar, A.2    Lev, D.3
  • 2
    • 67649388216 scopus 로고    scopus 로고
    • Current status of sporadic and neurofi bromatosis type 1-associated malignant peripheral nerve sheath tumors
    • Widemann BC,. Current status of sporadic and neurofi bromatosis type 1-associated malignant peripheral nerve sheath tumors. Curr Oncol Rep 2009; 11: 322-328.
    • (2009) Curr Oncol Rep , vol.11 , pp. 322-328
    • Widemann, B.C.1
  • 3
    • 67649209942 scopus 로고    scopus 로고
    • Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome
    • Zou C, Smith KD, Liu J, et al., Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg 2009; 249 (6): 1014-1022.
    • (2009) Ann Surg , vol.249 , Issue.6 , pp. 1014-1022
    • Zou, C.1    Smith, K.D.2    Liu, J.3
  • 4
    • 33747872815 scopus 로고    scopus 로고
    • Malignant peripheral nerve sheath tumors: Prognostic factors and survival in a series of patients treated at a single institution
    • Anghileri M, Miceli R, Fiore M, et al., Malignant peripheral nerve sheath tumors: prognostic factors and survival in a series of patients treated at a single institution. Cancer 2006; 107 (5): 1065-1074.
    • (2006) Cancer , vol.107 , Issue.5 , pp. 1065-1074
    • Anghileri, M.1    Miceli, R.2    Fiore, M.3
  • 5
    • 22544487213 scopus 로고    scopus 로고
    • Association between benign and malignant peripheral nerve sheath tumors in NF1
    • Tucker T, Wolkenstein P, Revuz J, et al., Association between benign and malignant peripheral nerve sheath tumors in NF1. Neurology 2005; 65 (2): 205-211.
    • (2005) Neurology , vol.65 , Issue.2 , pp. 205-211
    • Tucker, T.1    Wolkenstein, P.2    Revuz, J.3
  • 6
    • 75449091573 scopus 로고    scopus 로고
    • What's new in neurofibromatosis? Proceedings from the 2009 NF conference: New frontiers
    • Kissil JL, Blakeley JO, Ferner RE, et al., What's new in neurofibromatosis? Proceedings from the 2009 NF conference: new frontiers. Am J Med Genet A 2010; 152A (2): 269-283.
    • (2010) Am J Med Genet A , vol.152 A , Issue.2 , pp. 269-283
    • Kissil, J.L.1    Blakeley, J.O.2    Ferner, R.E.3
  • 7
    • 66849131261 scopus 로고    scopus 로고
    • Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor
    • Zou CY, Smith KD, Zhu Q-S, et al., Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Therap 2009; 8 (5): 1157-1168.
    • (2009) Mol Cancer Therap , vol.8 , Issue.5 , pp. 1157-1168
    • Zou, C.Y.1    Smith, K.D.2    Zhu, Q.-S.3
  • 8
    • 78651390321 scopus 로고    scopus 로고
    • Autophagic survival in resistance to histone deacetylase inhibitors: Novel strategies to treat malignant peripheral nerve sheath tumors
    • Lopez G, Torres K, Liu J, et al., Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Res 2011; 71 (1): 185-196.
    • (2011) Cancer Res , vol.71 , Issue.1 , pp. 185-196
    • Lopez, G.1    Torres, K.2    Liu, J.3
  • 9
    • 49849084685 scopus 로고    scopus 로고
    • Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors
    • Johansson G, Mahller YY, Collins MH, et al., Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Mol Cancer Ther 2008; 7 (5): 1237-1245.
    • (2008) Mol Cancer Ther , vol.7 , Issue.5 , pp. 1237-1245
    • Johansson, G.1    Mahller, Y.Y.2    Collins, M.H.3
  • 10
    • 79959226237 scopus 로고    scopus 로고
    • Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors
    • Torres KE, Zhu Q-S, Bill K, et al., Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors. Clin Cancer Res 2011; 17 (12): 3943-3955.
    • (2011) Clin Cancer Res , vol.17 , Issue.12 , pp. 3943-3955
    • Torres, K.E.1    Zhu, Q.-S.2    Bill, K.3
  • 11
    • 38549108547 scopus 로고    scopus 로고
    • Induction of abnormal proliferation by nonmyelinating Schwann cells triggers neurofibroma formation
    • Zheng H, Chang L, Patel N, et al., Induction of abnormal proliferation by nonmyelinating Schwann cells triggers neurofibroma formation. Cancer Cell 2008; 13 (2): 117-128.
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 117-128
    • Zheng, H.1    Chang, L.2    Patel, N.3
  • 12
    • 38549108007 scopus 로고    scopus 로고
    • Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells
    • Wu J, Williams JP, Rizvi TA, et al., Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell 2008; 13 (2): 105-116.
    • (2008) Cancer Cell , vol.13 , Issue.2 , pp. 105-116
    • Wu, J.1    Williams, J.P.2    Rizvi, T.A.3
  • 13
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • Cao R, Zhang Y,. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr Opin Genet Dev 2004; 14 (2): 155-164.
    • (2004) Curr Opin Genet Dev , vol.14 , Issue.2 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 14
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • Simon J, Lange C,. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008; 647: 21-29.
    • (2008) Mutat Res , vol.647 , pp. 21-29
    • Simon, J.1    Lange, C.2
  • 15
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • Simon JA, Lange CA,. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008; 647 (1-2): 21-29.
    • (2008) Mutat Res , vol.647 , Issue.12 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 16
    • 80054991835 scopus 로고    scopus 로고
    • PDGF signalling controls age-dependent proliferation in pancreatic (bgr)-cells
    • Chen H, Gu X, Liu Y, et al., PDGF signalling controls age-dependent proliferation in pancreatic (bgr)-cells. Nature 2011; 478 (7369): 349-355.
    • (2011) Nature , vol.478 , Issue.7369 , pp. 349-355
    • Chen, H.1    Gu, X.2    Liu, Y.3
  • 17
    • 84867987203 scopus 로고    scopus 로고
    • EZH2 inhibition: Targeting the crossroad of tumor invasion and angiogenesis
    • Crea F, Fornaro L, Bocci G, et al., EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis. Cancer Metast Rev 2012; 31 (3-4): 753-761.
    • (2012) Cancer Metast Rev , vol.31 , Issue.34 , pp. 753-761
    • Crea, F.1    Fornaro, L.2    Bocci, G.3
  • 18
    • 84856466661 scopus 로고    scopus 로고
    • The role of EZH2 in tumour progression
    • Chang CJ, Hung MC,. The role of EZH2 in tumour progression. Br J Cancer 2012; 106 (2): 243-247.
    • (2012) Br J Cancer , vol.106 , Issue.2 , pp. 243-247
    • Chang, C.J.1    Hung, M.C.2
  • 19
    • 84867606040 scopus 로고    scopus 로고
    • Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B cell lymphomas
    • Zhang X, Zhao X, Fiskus W, et al., Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B cell lymphomas. Cancer Cell 2012; 22 (4): 506-523.
    • (2012) Cancer Cell , vol.22 , Issue.4 , pp. 506-523
    • Zhang, X.1    Zhao, X.2    Fiskus, W.3
  • 20
    • 80051590718 scopus 로고    scopus 로고
    • Coordinated regulation of polycomb group complexes through microRNAs in cancer
    • Cao Q, Mani R-S, Ateeq B, et al., Coordinated regulation of polycomb group complexes through microRNAs in cancer. Cancer Cell 2011; 20 (2): 187-199.
    • (2011) Cancer Cell , vol.20 , Issue.2 , pp. 187-199
    • Cao, Q.1    Mani, R.-S.2    Ateeq, B.3
  • 21
    • 84859408905 scopus 로고    scopus 로고
    • MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling
    • Zhang P, Bill K, Liu J, et al., MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling. Cancer Res 2012; 72 (7): 1751-1762.
    • (2012) Cancer Res , vol.72 , Issue.7 , pp. 1751-1762
    • Zhang, P.1    Bill, K.2    Liu, J.3
  • 22
    • 42049095870 scopus 로고    scopus 로고
    • MicroRNA expression profiling using microarrays
    • Liu C-G, Calin GA, Volinia S, et al., MicroRNA expression profiling using microarrays. Nat Protoc 2008; 3 (4): 563-578.
    • (2008) Nat Protoc , vol.3 , Issue.4 , pp. 563-578
    • Liu, C.-G.1    Calin, G.A.2    Volinia, S.3
  • 23
    • 73649129263 scopus 로고    scopus 로고
    • Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours
    • Subramanian S, Thayanithy V, West RB, et al., Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours. J Pathol 2010; 220 (1): 58-70.
    • (2010) J Pathol , vol.220 , Issue.1 , pp. 58-70
    • Subramanian, S.1    Thayanithy, V.2    West, R.B.3
  • 24
    • 62449215108 scopus 로고    scopus 로고
    • The Karyopherin proteins, Crm1 and Karyopherin-β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation
    • van der Watt PJ, Maske CP, Hendricks DT, et al., The Karyopherin proteins, Crm1 and Karyopherin-β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation. Int J Cancer 2009; 124 (8): 1829-1840.
    • (2009) Int J Cancer , vol.124 , Issue.8 , pp. 1829-1840
    • Van Der Watt, P.J.1    Maske, C.P.2    Hendricks, D.T.3
  • 25
    • 36749081534 scopus 로고    scopus 로고
    • Crossing the nuclear envelope: Hierarchical regulation of nucleocytoplasmic transport
    • Terry LJ, Shows EB, Wente SR,. Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport. Science 2007; 318 (5855): 1412-1416.
    • (2007) Science , vol.318 , Issue.5855 , pp. 1412-1416
    • Terry, L.J.1    Shows, E.B.2    Wente, S.R.3
  • 26
    • 80955176375 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: First implications
    • Ciarapica R, Miele L, Giordano A, et al., Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. BMC Med 2011; 9 (1): 63.
    • (2011) BMC Med , vol.9 , Issue.1 , pp. 63
    • Ciarapica, R.1    Miele, L.2    Giordano, A.3
  • 27
    • 0034913423 scopus 로고    scopus 로고
    • Importin-β-like nuclear transport receptors
    • reviews 3008.
    • Strom AC, Weis K,. Importin-β-like nuclear transport receptors. Genome Biol 2001; 2 (6): reviews 3008.
    • (2001) Genome Biol , vol.2 , Issue.6
    • Strom, A.C.1    Weis, K.2
  • 28
    • 14544272335 scopus 로고    scopus 로고
    • Regulation of nuclear transport: Central role in development and transformation?
    • Poon IK, Jans DA,. Regulation of nuclear transport: central role in development and transformation? Traffic 2005; 6 (3): 173-186.
    • (2005) Traffic , vol.6 , Issue.3 , pp. 173-186
    • Poon, I.K.1    Jans, D.A.2


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