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Volumn 87, Issue 1, 2014, Pages 131-139

Animal models of asthma: Reprise or reboot?

Author keywords

Animal models; Asthma; Asthma phenotypes; T cell immunity; Translational pharmacology

Indexed keywords

ALLERGEN; BRONCHODILATING AGENT; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 13; LEBRIKIZUMAB; MONOCLONAL ANTIBODY; OVALBUMIN; TRALOKINUMAB;

EID: 84892374397     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.06.026     Document Type: Review
Times cited : (61)

References (83)
  • 3
    • 77956394681 scopus 로고    scopus 로고
    • 2- agonists: The importance of striking the right balance between risks and benefits of therapy?
    • 2-agonists: the importance of striking the right balance between risks and benefits of therapy? J Allergy Clin Immunol 126 2010 449 452
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 449-452
    • Lemanske, Jr.R.F.1    Busse, W.W.2
  • 4
    • 80052915442 scopus 로고    scopus 로고
    • Omalizumab: The evidence for its place in the treatment of allergic asthma
    • D.M. McNicholl, and L.G. Heaney Omalizumab: the evidence for its place in the treatment of allergic asthma Core Evid 3 2008 55 66
    • (2008) Core Evid , vol.3 , pp. 55-66
    • McNicholl, D.M.1    Heaney, L.G.2
  • 6
    • 35648929946 scopus 로고    scopus 로고
    • Asthma cases attributable to atopy: Results from the Third National Health and Nutrition Examination Survey
    • DOI 10.1016/j.jaci.2007.07.056, PII S0091674907014601
    • S.J. Arbes, P.J. Gergen, B. Vaughn, and D.C. Zeldin Asthma cases attributable to atopy: results from the third National Health and Nutrition Examination Survey J Alleregy Clin Immunol 120 2007 1139 1145 (Pubitemid 350029902)
    • (2007) Journal of Allergy and Clinical Immunology , vol.120 , Issue.5 , pp. 1139-1145
    • Arbes Jr., S.J.1    Gergen, P.J.2    Vaughn, B.3    Zeldin, D.C.4
  • 7
    • 69349104813 scopus 로고    scopus 로고
    • Total IgE and asthma prevalence in the US population: Results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006
    • P.J. Gergen, S.J. Arbes, A. Calatroni, H.E. Mitchell, and D.C. Zeldin Total IgE and asthma prevalence in the US population: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006 J Allergy Clin Immunol 124 2009 447 453
    • (2009) J Allergy Clin Immunol , vol.124 , pp. 447-453
    • Gergen, P.J.1    Arbes, S.J.2    Calatroni, A.3    Mitchell, H.E.4    Zeldin, D.C.5
  • 8
    • 77649119443 scopus 로고    scopus 로고
    • Disordered microbial communities in asthmatic airways
    • M. Hilty, C. Burke, H. Pedro, P. Cardenas, and A. Bush et al. Disordered microbial communities in asthmatic airways PLoS ONE 5 2010 e8578
    • (2010) PLoS ONE , vol.5 , pp. 8578
    • Hilty, M.1    Burke, C.2    Pedro, H.3    Cardenas, P.4    Bush, A.5
  • 9
    • 84869207266 scopus 로고    scopus 로고
    • Nous sommes tous des bacteries: Implications for medicine, pharmacology and public health
    • D.J. Triggle Nous sommes tous des bacteries: implications for medicine, pharmacology and public health Biochem Pharmacol 84 2012 1543 1550
    • (2012) Biochem Pharmacol , vol.84 , pp. 1543-1550
    • Triggle, D.J.1
  • 10
    • 84892367364 scopus 로고    scopus 로고
    • Animal models of human disease: Inflammation
    • Webb D Animal models of human disease: inflammation Biochem Pharm 87 2014 121 130
    • (2014) Biochem Pharm , vol.87 , pp. 121-130
    • Webb, D.1
  • 11
    • 80051670719 scopus 로고    scopus 로고
    • Animal models of asthma: Value, limitations and opportunities for alternative approaches
    • A.M. Holmes, R. Solari, and S.T. Holgate Animal models of asthma: value, limitations and opportunities for alternative approaches Drug Discov Today 16 2011 659 670
    • (2011) Drug Discov Today , vol.16 , pp. 659-670
    • Holmes, A.M.1    Solari, R.2    Holgate, S.T.3
  • 12
    • 78649516124 scopus 로고    scopus 로고
    • Functions of T cells in asthma: More than just Th2 cells
    • C.M. Lloyd, and E.M. Hessel Functions of T cells in asthma: more than just Th2 cells Nat Rev Immunol 10 2010 838 848
    • (2010) Nat Rev Immunol , vol.10 , pp. 838-848
    • Lloyd, C.M.1    Hessel, E.M.2
  • 13
    • 80051548418 scopus 로고    scopus 로고
    • Asthma translational medicine: Report card
    • K. Mullane Asthma translational medicine: report card Biochem Pharmacol 82 2011 567 585
    • (2011) Biochem Pharmacol , vol.82 , pp. 567-585
    • Mullane, K.1
  • 14
    • 33644774556 scopus 로고    scopus 로고
    • Asthma genetics 2006: The long and winding road to gene discovery
    • DOI 10.1038/sj.gene.6364284, PII 6364284
    • C. Ober, and S. Hoffjan Asthma genetics 2006: the long and winding road to gene discovery Genes Immun 7 2006 95 100 (Pubitemid 43336051)
    • (2006) Genes and Immunity , vol.7 , Issue.2 , pp. 95-100
    • Ober, C.1    Hoffjan, S.2
  • 15
    • 84871973438 scopus 로고    scopus 로고
    • Genome-wide association studies in asthma: What they really told us about pathogenesis
    • M. Wjst, M. Sargurupremraj, and M. Arnold Genome-wide association studies in asthma: what they really told us about pathogenesis Curr Opin Allergy Clin Immunol 13 2013 112 118
    • (2013) Curr Opin Allergy Clin Immunol , vol.13 , pp. 112-118
    • Wjst, M.1    Sargurupremraj, M.2    Arnold, M.3
  • 16
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • M.F. Moffatt, I.G. Gut, F. Demenais, D.P. Strachan, and E. Bouzigon et al. A large-scale, consortium-based genomewide association study of asthma New Engl J Med 363 2010 1211 1221
    • (2010) New Engl J Med , vol.363 , pp. 1211-1221
    • Moffatt, M.F.1    Gut, I.G.2    Demenais, F.3    Strachan, D.P.4    Bouzigon, E.5
  • 17
    • 80052947350 scopus 로고    scopus 로고
    • Genome-wide association studies have not been useful in understanding asthma
    • I.M. Adcock, and Barnes P.J. Con Genome-wide association studies have not been useful in understanding asthma Am J Respir Crit Care Med 184 2011 633 636
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 633-636
    • Adcock, I.M.1    Con, B.P.J.2
  • 18
    • 80655149205 scopus 로고    scopus 로고
    • New IBD genetics: Common pathways with other diseases
    • C.W. Lees, J.C. Barrett, M. Parkes, and J. Satsangi New IBD genetics: common pathways with other diseases Gut 60 2011 1739 1753
    • (2011) Gut , vol.60 , pp. 1739-1753
    • Lees, C.W.1    Barrett, J.C.2    Parkes, M.3    Satsangi, J.4
  • 19
    • 84867375353 scopus 로고    scopus 로고
    • ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6
    • M. Miller, A.B. Tam, J.Y. Cho, T.A. Doherty, and A. Pham et al. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6 Proc Natn Acad Sci 109 2012 16648 16653
    • (2012) Proc Natn Acad Sci , vol.109 , pp. 16648-16653
    • Miller, M.1    Tam, A.B.2    Cho, J.Y.3    Doherty, T.A.4    Pham, A.5
  • 20
    • 84881156244 scopus 로고    scopus 로고
    • Genome-wide association study identifies Th1 pathway genes associated with lung function in asthmatic patients
    • 10.1016/j.jaci.2013.01.051
    • X. Li, G.A. Hawkins, E.J. Ampleford, W.C. Moore, and H. Li et al. Genome-wide association study identifies Th1 pathway genes associated with lung function in asthmatic patients J Allergy Clin Immunol 2013 10.1016/j.jaci.2013. 01.051
    • (2013) J Allergy Clin Immunol
    • Li, X.1    Hawkins, G.A.2    Ampleford, E.J.3    Moore, W.C.4    Li, H.5
  • 21
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: The evolution from clinical to molecular approaches
    • S.E. Wenzel Asthma phenotypes: the evolution from clinical to molecular approaches Nature Med 18 2012 716 725
    • (2012) Nature Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 22
    • 84862024217 scopus 로고    scopus 로고
    • Untangling asthma phenotypes and endotypes
    • I. Agache, C. Akdis, M. Jutel, and J.C. Virchow Untangling asthma phenotypes and endotypes Allergy 67 2012 835 846
    • (2012) Allergy , vol.67 , pp. 835-846
    • Agache, I.1    Akdis, C.2    Jutel, M.3    Virchow, J.C.4
  • 23
    • 77951666051 scopus 로고    scopus 로고
    • Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples
    • M.T. Al-Samri, A. Benedetti, D. Prefontaine, R. Olivenstein, and C. Lemiere et al. Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: a prospective study using multiple samples J Allergy Clin Immunol 125 2010 1161 1163
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1161-1163
    • Al-Samri, M.T.1    Benedetti, A.2    Prefontaine, D.3    Olivenstein, R.4    Lemiere, C.5
  • 25
    • 79251582522 scopus 로고    scopus 로고
    • Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways
    • D.F. Choy, B. Modrek, A.R. Abbas, S. Kummerfeld, and H.F. Clark et al. Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways J Immunol 186 2011 1861 1869
    • (2011) J Immunol , vol.186 , pp. 1861-1869
    • Choy, D.F.1    Modrek, B.2    Abbas, A.R.3    Kummerfeld, S.4    Clark, H.F.5
  • 27
    • 84873389433 scopus 로고    scopus 로고
    • A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma
    • E. Piper, C. Brightling, R. Niven, C. Oh, and R. Faggioni et al. A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma Eur Resp J 41 2013 330 338
    • (2013) Eur Resp J , vol.41 , pp. 330-338
    • Piper, E.1    Brightling, C.2    Niven, R.3    Oh, C.4    Faggioni, R.5
  • 28
    • 0034881918 scopus 로고    scopus 로고
    • New insights into the role of cytokines in asthma
    • DOI 10.1136/jcp.54.8.577
    • J-C. Renauld New insights into the role of cytokines in asthma J Clin Pathol 54 2001 577 589 (Pubitemid 32756438)
    • (2001) Journal of Clinical Pathology , vol.54 , Issue.8 , pp. 577-589
    • Renauld, J.-C.1
  • 31
    • 84865696394 scopus 로고    scopus 로고
    • Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
    • G. Jia, R.W. Erickson, D.F. Choy, S. Mosesova, and L.C. Wu et al. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients J Allergy Clin Immunol 130 2012 647 654
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 647-654
    • Jia, G.1    Erickson, R.W.2    Choy, D.F.3    Mosesova, S.4    Wu, L.C.5
  • 32
    • 82755178696 scopus 로고    scopus 로고
    • A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness
    • E.D. Gordon, S.S. Sidhu, Z.E. Wang, P.G. Woodruff, and S. Yuan et al. A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness Clin Exp Allergy 42 2012 144 155
    • (2012) Clin Exp Allergy , vol.42 , pp. 144-155
    • Gordon, E.D.1    Sidhu, S.S.2    Wang, Z.E.3    Woodruff, P.G.4    Yuan, S.5
  • 33
    • 47749152971 scopus 로고    scopus 로고
    • Experimental bronchial asthma - The strength of the species rat
    • DOI 10.2174/138945008784533543
    • T. Tschernig, D. Neumann, A. Pich, M. Dorsch, and R. Pabst Experimental bronchial asthma - the strength of the species rat Curr Drug Targets 9 2008 466 469 (Pubitemid 352025203)
    • (2008) Current Drug Targets , vol.9 , Issue.6 , pp. 466-469
    • Tschernig, T.1    Neumann, D.2    Pich, A.3    Dorsch, M.4    Pabst, R.5
  • 35
    • 50849094871 scopus 로고    scopus 로고
    • The rabbit as a model to study asthma and other lung diseases
    • S. Keir, and C. Page The rabbit as a model to study asthma and other lung diseases Pulm Pharmacol Ther 21 2008 721 730
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 721-730
    • Keir, S.1    Page, C.2
  • 37
    • 50849140491 scopus 로고    scopus 로고
    • Modeling of asthma, COPD and cystic fibrosis in sheep
    • W.M. Abraham Modeling of asthma, COPD and cystic fibrosis in sheep Pulm Pharmacol Ther 21 2008 743 754
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 743-754
    • Abraham, W.M.1
  • 38
    • 50849090306 scopus 로고    scopus 로고
    • The non-human primate as a model for studying COPD and asthma
    • C.G. Plopper, and D.H. Hyde The non-human primate as a model for studying COPD and asthma Pulm Pharmacol Ther 21 2008 755 766
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 755-766
    • Plopper, C.G.1    Hyde, D.H.2
  • 39
  • 43
    • 34249025784 scopus 로고    scopus 로고
    • Building better mouse models of asthma
    • C.M. Lloyd Building better mouse models of asthma Curr Allergy Asthma Rep 7 2007 231 236 (Pubitemid 46784202)
    • (2007) Current Allergy and Asthma Reports , vol.7 , Issue.3 , pp. 231-236
    • Lloyd, C.M.1
  • 44
    • 80051930931 scopus 로고    scopus 로고
    • Orchestrating house dust mite-associated allergy in the lung
    • L.G. Gregory, and C.M. Lloyd Orchestrating house dust mite-associated allergy in the lung Trends Immunol 32 2011 402 411
    • (2011) Trends Immunol , vol.32 , pp. 402-411
    • Gregory, L.G.1    Lloyd, C.M.2
  • 45
    • 84866465887 scopus 로고    scopus 로고
    • Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?
    • 10.3389/fphys.2012.00312
    • R.K. Kumar, and P.S. Foster Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness? Front Physiol 3 2012 10.3389/fphys.2012.00312
    • (2012) Front Physiol , vol.3
    • Kumar, R.K.1    Foster, P.S.2
  • 46
    • 80053237344 scopus 로고    scopus 로고
    • Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model
    • A.R. Abbas, J.K. Jackman, S.L. Bullens, S.M. Davis, and D.F. Choy et al. Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model Am J Pathol 179 2011 1667 1680
    • (2011) Am J Pathol , vol.179 , pp. 1667-1680
    • Abbas, A.R.1    Jackman, J.K.2    Bullens, S.L.3    Davis, S.M.4    Choy, D.F.5
  • 47
    • 0025293523 scopus 로고
    • Utility of animal models in the study of human airway disease
    • A. Wanner Utility of animal models in the study of human airway disease Chest 98 1990 211 217 (Pubitemid 20223692)
    • (1990) Chest , vol.98 , Issue.1 , pp. 211-217
    • Wanner, A.1
  • 48
    • 0032768264 scopus 로고    scopus 로고
    • Current animal models are not predictive for clinical asthma
    • DOI 10.1006/pupt.1999.0193
    • R.A. Coleman Current animal models are not predictive for clinical asthma Pulm Pharmacol Ther 12 1999 87 89 (Pubitemid 29366499)
    • (1999) Pulmonary Pharmacology and Therapeutics , vol.12 , Issue.2 , pp. 87-89
    • Coleman, R.A.1
  • 49
    • 33845870421 scopus 로고    scopus 로고
    • Promise and pitfalls in animal-based asthma research: Building a better mousetrap
    • DOI 10.1385/IR:35:3:279, PII IR353279
    • D.B. Corry, and C.G. Irvin Promise and pitfalls in animal-based asthma research: building a better mousetrap Immunol Res 35 2006 279 294 (Pubitemid 46020728)
    • (2006) Immunologic Research , vol.35 , Issue.3 , pp. 279-294
    • Corry, D.B.1    Irvin, C.G.2
  • 52
    • 22344457252 scopus 로고    scopus 로고
    • No audible wheezing: Nuggets and conundrums from mouse asthma models
    • DOI 10.1084/jem.20050584
    • J.A. Boyce, and K.F. Austen No audible wheezing: nuggets and conundrums from mouse asthma models J Exp Med 201 2005 1869 1873 (Pubitemid 41002921)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.12 , pp. 1869-1873
    • Boyce, J.A.1    Austen, K.F.2
  • 54
    • 80255137163 scopus 로고    scopus 로고
    • Harnessing opportunities in non-animal asthma research for a 21st-century science
    • G.L. Buckland Harnessing opportunities in non-animal asthma research for a 21st-century science Drug Discov Today 16 2011 914 927
    • (2011) Drug Discov Today , vol.16 , pp. 914-927
    • Buckland, G.L.1
  • 55
    • 77956623567 scopus 로고    scopus 로고
    • A look at the pathogenesis of asthma: The need for a change in direction
    • S.T. Holgate A look at the pathogenesis of asthma: the need for a change in direction Discov Med 9 2010 439 447
    • (2010) Discov Med , vol.9 , pp. 439-447
    • Holgate, S.T.1
  • 57
    • 67649805319 scopus 로고    scopus 로고
    • An official American Thoracic Society/European Respiratory Society statement: Asthma control and exacerbations
    • H.K. Reddel, D.R. Taylor, E.D. Bateman, L.-P. Boulet, and H.A. Boushey et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations Am J Respir Crit Care Med 180 2009 59 99
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 59-99
    • Reddel, H.K.1    Taylor, D.R.2    Bateman, E.D.3    Boulet, L.-P.4    Boushey, H.A.5
  • 58
    • 77953119597 scopus 로고    scopus 로고
    • Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma
    • S. Fernandez-Rodriguez, K.J. Broadley, W.R. Ford, and E.J. Kidd Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma Pulm Pharmacol Ther 23 2010 300 307
    • (2010) Pulm Pharmacol Ther , vol.23 , pp. 300-307
    • Fernandez-Rodriguez, S.1    Broadley, K.J.2    Ford, W.R.3    Kidd, E.J.4
  • 59
    • 84859720060 scopus 로고    scopus 로고
    • Preclinical development of CAT-345, an IL-13 neutralizing antibody, for the treatment of severe uncontrolled asthma
    • R.D. May, P.D. Monk, E.S. Cohen, D. Manuel, and F. Dempsey et al. Preclinical development of CAT-345, an IL-13 neutralizing antibody, for the treatment of severe uncontrolled asthma Brit J Pharmacol 166 2012 177 193
    • (2012) Brit J Pharmacol , vol.166 , pp. 177-193
    • May, R.D.1    Monk, P.D.2    Cohen, E.S.3    Manuel, D.4    Dempsey, F.5
  • 60
    • 84883759824 scopus 로고    scopus 로고
    • Assessment of murine lung mechanics outcome measures: Alignment with those made in asthmatics
    • 10.3389/fphysiol.2012.00491
    • J.K.L. Walker, M. Kraft, and Fisher JT Assessment of murine lung mechanics outcome measures: alignment with those made in asthmatics Front Physiol 3 2013 10.3389/fphysiol.2012.00491
    • (2013) Front Physiol , vol.3
    • Walker, J.K.L.1    Kraft, M.2    Jt, F.3
  • 61
    • 84873166660 scopus 로고    scopus 로고
    • Models to study airway smooth muscle contractions in vivo, ex vivo and in vitro: Implications in understanding asthma
    • D. Wright, P. Sharma, M-H. Ryu, P-A. Risse, and M. Ngo et al. Models to study airway smooth muscle contractions in vivo, ex vivo and in vitro: implications in understanding asthma Pulm Pharmacol Ther 26 2013 24 36
    • (2013) Pulm Pharmacol Ther , vol.26 , pp. 24-36
    • Wright, D.1    Sharma, P.2    Ryu, M.-H.3    Risse, P.-A.4    Ngo, M.5
  • 62
    • 78651372560 scopus 로고    scopus 로고
    • Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice
    • A. Berndt, A.S. Leme, L.K. Williams, R. Von Smith, and H.S. Savage et al. Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice Physiol Genomics 43 2011 1 11
    • (2011) Physiol Genomics , vol.43 , pp. 1-11
    • Berndt, A.1    Leme, A.S.2    Williams, L.K.3    Von Smith, R.4    Savage, H.S.5
  • 63
    • 84874004801 scopus 로고    scopus 로고
    • Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene
    • B.E. Himes, K. Sheppard, A. Berndt, A.S. Leme, and R.A. Myers et al. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene PLoS 8 2013 e56179
    • (2013) PLoS , vol.8 , pp. 56179
    • Himes, B.E.1    Sheppard, K.2    Berndt, A.3    Leme, A.S.4    Myers, R.A.5
  • 64
    • 80051548564 scopus 로고    scopus 로고
    • The increasing challenge of discovering asthma drugs
    • K. Mullane The increasing challenge of discovering asthma drugs Biochem Pharmacol 82 2011 586 599
    • (2011) Biochem Pharmacol , vol.82 , pp. 586-599
    • Mullane, K.1
  • 67
    • 84873369705 scopus 로고    scopus 로고
    • β2-adrenoceptor agonists are required for development of the asthma phenotype in a murine model
    • V.J. Thanawala, G.S. Forkuo, N. Al-Sawalha, Z. Azzegagh, and L.P. Nguyen et al. β2-adrenoceptor agonists are required for development of the asthma phenotype in a murine model Am J Respir Cell Mol Biol 48 2013 220 229
    • (2013) Am J Respir Cell Mol Biol , vol.48 , pp. 220-229
    • Thanawala, V.J.1    Forkuo, G.S.2    Al-Sawalha, N.3    Azzegagh, Z.4    Nguyen, L.P.5
  • 68
    • 77954357471 scopus 로고    scopus 로고
    • Effect of tiotropium bromide on airway inflammation and remodeling in a mouse model of asthma
    • S. Ohta, N. Oda, T. Yokoe, A. Tanaka, and Y. Yamamoto et al. Effect of tiotropium bromide on airway inflammation and remodeling in a mouse model of asthma Clin Exp Allergy 40 2010 1266 1275
    • (2010) Clin Exp Allergy , vol.40 , pp. 1266-1275
    • Ohta, S.1    Oda, N.2    Yokoe, T.3    Tanaka, A.4    Yamamoto, Y.5
  • 71
    • 77954075135 scopus 로고    scopus 로고
    • Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation
    • K. Takeda, Y. Shiraishi, S. Matsubara, N. Miyahara, and H. Matsuda et al. Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation Brit J Pharmacol 160 2010 1399 1407
    • (2010) Brit J Pharmacol , vol.160 , pp. 1399-1407
    • Takeda, K.1    Shiraishi, Y.2    Matsubara, S.3    Miyahara, N.4    Matsuda, H.5
  • 72
    • 12444292117 scopus 로고    scopus 로고
    • Differential effects of fluticasone and montelukast on allergen-induced asthma
    • M. Palmqvist, C. Bruce, M. Sjostrand, P. Arvidsson, and J. Lotvall Differential effects of fluticasone and montelukast on allergen-induced asthma Allergy 60 2005 65 70
    • (2005) Allergy , vol.60 , pp. 65-70
    • Palmqvist, M.1    Bruce, C.2    Sjostrand, M.3    Arvidsson, P.4    Lotvall, J.5
  • 73
    • 77957069991 scopus 로고    scopus 로고
    • Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus
    • J. Han, Y. Jia, K. Takeda, Y. Shiraishi, and M. Okamoto et al. Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus Am J Respir Crit Care Med 182 2010 455 463
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 455-463
    • Han, J.1    Jia, Y.2    Takeda, K.3    Shiraishi, Y.4    Okamoto, M.5
  • 75
    • 0033037430 scopus 로고    scopus 로고
    • Suppression of immediate and late responses to antigen by a non- anaphylactogenic anti-IgE antibody in a murine model of asthma
    • DOI 10.1034/j.1399-3003.1999.13e06.x
    • S. Haile, J. Lefort, S.Y. Eum, M. Huerre, C. Heusser, and B.B. Vargaftig Suppression of immediate and late responses to antigen by a non-anaphylactogenic anti-IgE antibody in a murine model of asthma Eur Resp J 13 1999 961 969 (Pubitemid 29288915)
    • (1999) European Respiratory Journal , vol.13 , Issue.5 , pp. 961-969
    • Haile, S.1    Lefort, J.2    Eum, S.Y.3    Dumarey, C.4    Huerre, M.5    Heusser, C.6    Vargaftig, B.B.7
  • 76
    • 8244226656 scopus 로고    scopus 로고
    • Inhibitory effects of an anti-igE antibody E25 on allergen-induced early asthmatic response
    • L.P. Boulet, K.R. Chapman, J. Cote, S. Kalra, and R. Bhagat et al. Inhibitory effects of an anti-igE antibody E25 on allergen-induced early asthmatic response Am J Respir Crit Care Med 155 1997 1835 1840
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1835-1840
    • Boulet, L.P.1    Chapman, K.R.2    Cote, J.3    Kalra, S.4    Bhagat, R.5
  • 77
    • 17744376022 scopus 로고    scopus 로고
    • Anti-immunoglobulin E treatment with omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
    • DOI 10.1111/j.1365-2222.2005.02191.x
    • S.T. Holgate, R. Djukanovic, T. Casale, and J. Bousquet Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy Clin Exp Allergy 35 2005 408 416 (Pubitemid 40577231)
    • (2005) Clinical and Experimental Allergy , vol.35 , Issue.4 , pp. 408-416
    • Holgate, S.T.1    Djukanovic, R.2    Casale, T.3    Bousquet, J.4
  • 78
    • 84869239729 scopus 로고    scopus 로고
    • New cell for asthma: Enter the myeloid
    • T.J. Williams New cell for asthma: enter the myeloid Thorax 67 2012 1114 1115
    • (2012) Thorax , vol.67 , pp. 1114-1115
    • Williams, T.J.1
  • 79
    • 84862528505 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Past, present, and future
    • S. Yamanaka Induced pluripotent stem cells: past, present, and future Cell Stem Cell 10 2012 678 684
    • (2012) Cell Stem Cell , vol.10 , pp. 678-684
    • Yamanaka, S.1
  • 80
    • 84873733109 scopus 로고    scopus 로고
    • A TALEN genome-editing system for generating human stem cell-based disease models
    • Q. Ding, Y-K. Lee, E.A.K. Schaefer, D.T. Peters, and A. Veres et al. A TALEN genome-editing system for generating human stem cell-based disease models Cell Stem Cell 12 2013 238 251
    • (2013) Cell Stem Cell , vol.12 , pp. 238-251
    • Ding, Q.1    Lee, Y.-K.2    Schaefer, E.A.K.3    Peters, D.T.4    Veres, A.5
  • 81
    • 77953973017 scopus 로고    scopus 로고
    • Allergen-induced airway inflammation and its therapeutic intervention
    • P.M. O'Byrne Allergen-induced airway inflammation and its therapeutic intervention Allergy Asthma Immunol Res 1 2009 3 9
    • (2009) Allergy Asthma Immunol Res , vol.1 , pp. 3-9
    • O'Byrne, P.M.1
  • 82
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
    • DOI 10.1016/S0140-6736(07)61600-6, PII S0140673607616006
    • S.E. Wenzel, D. Wilbraham, R. Fuller, E.B. Getz, and M. Longphre Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two Phase 2a studies Lancet 370 2007 1422 1431 (Pubitemid 47576168)
    • (2007) Lancet , vol.370 , Issue.9596 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3    Getz, E.B.4    Longphre, M.5
  • 83
    • 84892372761 scopus 로고    scopus 로고
    • American Lung Association. Trends in asthma morbidity and mortality. February 2010.
    • American Lung Association. Trends in asthma morbidity and mortality. February 2010. http://www.lungusa.org/finding-cures/our-research/trend-reports/ asthma-trend-report.pdf.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.