Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

International Journal of Molecular Sciences

Volumn 15, Issue 1, 2014, Pages 905-926

  Pamies, David ^a,b,c   Sogorb, Miguel A ^a   Fabbri, Marco ^b,d   Gribaldo, Laura ^b   Collotta, Angelo ^b   Scelfo, Bibiana ^b   Vilanova, Eugenio ^a   Harris, Georgina ^b,c   Bal Price, Anna ^b  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b JOINT RESEARCH CENTRE   (Italy)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Human embryonal carcinoma stem cells; Neurodevelopmental toxicity; Neurodifferentiation; NT2; NTE; Organophosphorus pesticides

Indexed keywords

4', 6 DIAMIDINO 2 PHENYLINDOLE; ACETYLCHOLINESTERASE; BETA TUBULIN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; HISTONE H1; HISTONE H2B; HISTONE H4; MESSENGER RNA; MIPAFOX; NEUROTOXIC ESTERASE; PARAOXON; RETINOIC ACID; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA MODIFICATION; DRUG EXPOSURE; EMBRYONAL CARCINOMA STEM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION; GENOMICS; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; MTT ASSAY; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROTOXICITY; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLURIPOTENT STEM CELL; TERATOGENESIS; ULTRAVIOLET SPECTROPHOTOMETRY;

CHROMATIN ASSEMBLY AND DISASSEMBLY; EMBRYONAL CARCINOMA STEM CELLS; GENOME, HUMAN; HISTONES; HUMANS; INSECTICIDES; ISOFLUROPHATE; NEUROGENESIS; NEURONS; NUCLEOSOMES; PARAOXON; PHENOTYPE; TRETINOIN;

EID: 84892155292     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15010905     Document Type: Article

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