An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE)

Toxicology in Vitro

Volumn 24, Issue 3, 2010, Pages 942-952

  Sogorb, Miguel A ^a   González González, Iván ^a   Pamies, David ^a   Vilanova, Eugenio ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

Alternative method; Delayed polyneuropathy; In vitro; Inhibition and aging; Neuroblastoma; NTE; Organophosphorus compound

Indexed keywords

ACETYLCHOLINESTERASE; LEPTOPHOS; MIPAFOX; NEUROTOXIC ESTERASE; ORGANOPHOSPHORUS COMPOUND; PARAOXON;

AGING; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; HEN; HUMAN; HUMAN CELL; IC 50; LONG TERM EXPOSURE; MATHEMATICAL MODEL; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; POLYNEUROPATHY; TOXICITY TESTING;

ACETYLCHOLINESTERASE; ALGORITHMS; ANIMALS; BRAIN; CARBOXYLIC ESTER HYDROLASES; CELL LINE; CHICKENS; CHOLINESTERASE INHIBITORS; DRUG RESISTANCE; ENZYME INHIBITORS; HUMANS; KINETICS; MODELS, STATISTICAL; NEUROTOXICITY SYNDROMES; NEUROTOXINS; ORGANOPHOSPHORUS COMPOUNDS; PARAOXON;

EID: 77649183580     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.01.008     Document Type: Article

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