Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment

Toxicology Letters

Volumn 217, Issue 1, 2013, Pages 14-22

  Estevan, Carmen ^a   Vilanova, Eugenio ^a   Sogorb, Miguel A ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

Chlorpyrifos; Chlorpyrifos oxon; Differentiation; Embryonic stem cell; Risk assessment

Indexed keywords

ACETYLCHOLINESTERASE; CHLORPYRIFOS; OCTAMER TRANSCRIPTION FACTOR 4; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DEGRADATION; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; EMBRYOTOXICITY; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; METABOLITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; UPREGULATION;

3T3 CELLS; ANIMALS; ANTIGENS, DIFFERENTIATION; BIOTRANSFORMATION; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CHLORPYRIFOS; CHOLINESTERASE INHIBITORS; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; INSECTICIDES; MICE; OSMOLAR CONCENTRATION; PLURIPOTENT STEM CELLS; PYRIDONES; RISK ASSESSMENT; TERATOGENS; TIME FACTORS;

EID: 84872161015     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.11.026     Document Type: Article

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