Role of genetic polymorphisms of CYP1A1, CYP3A5, CYP2C9, CYP2D6, and PON1 in the modulation of DNA damage in workers occupationally exposed to organophosphate pesticides

Toxicology and Applied Pharmacology

Volumn 257, Issue 1, 2011, Pages 84-92

  Singh, Satyender ^a   Kumar, Vivek ^b   Vashisht, Kapil ^a   Singh, Priyanka ^a   Banerjee, Basu Dev ^a   Rautela, Rajender Singh ^a   Grover, Shyam Sunder ^a   Rawat, Devendra Singh ^a   Pasha, Syed Tazeen ^a   Jain, Sudhir Kumar ^a   Rai, Arvind ^a  

^a National Centre for Disease Control 22   (India)

^b UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

Cytochrome P 450; DNA damage; Genetic polymorphisms; Organophosphate pesticides; PON1

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; CYTOCHROME P450 1A1; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A5; ORGANOPHOSPHATE PESTICIDE;

ADULT; ARTICLE; BLOOD SAMPLING; COMET ASSAY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ARYL HYDROCARBON HYDROXYLASES; ARYLDIALKYLPHOSPHATASE; COMET ASSAY; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 CYP3A; DNA DAMAGE; GENOTYPE; HUMANS; MIDDLE AGED; OCCUPATIONAL EXPOSURE; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 81255141977     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.08.021     Document Type: Article

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