-
1
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima, N. and Komatsu, M. (2011) Autophagy: renovation of cells and tissues. Cell 147, 728-741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
2
-
-
79959415069
-
Biogenesis and cargo selectivity of autophagosomes
-
Weidberg, H., Shvets, E. and Elazar, Z. (2011) Biogenesis and cargo selectivity of autophagosomes. Annu. Rev. Biochem. 80, 125-156
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 125-156
-
-
Weidberg, H.1
Shvets, E.2
Elazar, Z.3
-
3
-
-
80054025654
-
The role of Atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T. and Ohsumi, Y. (2012) The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27, 107-132
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
5
-
-
84859386792
-
Autophagy and the immune system
-
Kuballa, P., Nolte, W.M., Castoreno, A.B. and Xavier, R.J. (2012) Autophagy and the immune system. Annu. Rev. Immunol. 30, 611-646
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 611-646
-
-
Kuballa, P.1
Nolte, W.M.2
Castoreno, A.B.3
Xavier, R.J.4
-
6
-
-
84877323647
-
Regulation of nutrientsensitive autophagy by uncoordinated 51-like kinases 1 and 2
-
McAlpine, F., Williamson, L.E., Tooze, S.A. and Chan, E.Y. (2013) Regulation of nutrientsensitive autophagy by uncoordinated 51-like kinases 1 and 2. Autophagy 9, 361-373
-
(2013)
Autophagy
, vol.9
, pp. 361-373
-
-
McAlpine, F.1
Williamson, L.E.2
Tooze, S.A.3
Chan, E.Y.4
-
7
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim, J., Kundu, M., Viollet, B. and Guan, K.L. (2011) AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132-141
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
8
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan, D.F., Shackelford, D.B., Mihaylova, M.M., Gelino, S., Kohnz, R.A., Mair, W., Vasquez, D.S., Joshi, A., Gwinn, D.M., Taylor, R. et al. (2011) Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331, 456-461
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
-
9
-
-
0025363276
-
Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
-
Dunn, W. (1990) Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J. Cell Biol. 110, 1923-1933
-
(1990)
J. Cell Biol.
, vol.110
, pp. 1923-1933
-
-
Dunn, W.1
-
10
-
-
0026059280
-
Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver
-
Ueno, T., Muno, D. and Kominami, E. (1991) Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver. J. Biol. Chem. 266, 18995-18999
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18995-18999
-
-
Ueno, T.1
Muno, D.2
Kominami, E.3
-
11
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe, E.L., Walker, S.A., Manifava, M., Chandra, P., Roderick, H.L., Habermann, A., Griffiths, G. and Ktistakis, N.T. (2008) Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J. Cell Biol. 182, 685-701
-
(2008)
J. Cell Biol.
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
Chandra, P.4
Roderick, H.L.5
Habermann, A.6
Griffiths, G.7
Ktistakis, N.T.8
-
12
-
-
0035199161
-
FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments
-
Ridley, S.H., Ktistakis, N., Davidson, K., Anderson, K.E., Manifava, M., Ellson, C.D., Lipp, P., Bootman, M., Coadwell, J., Nazarian, A. et al. (2001) FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments. J. Cell Sci. 114, 3991-4000
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3991-4000
-
-
Ridley, S.H.1
Ktistakis, N.2
Davidson, K.3
Anderson, K.E.4
Manifava, M.5
Ellson, C.D.6
Lipp, P.7
Bootman, M.8
Coadwell, J.9
Nazarian, A.10
-
13
-
-
77953507889
-
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation
-
Hayashi-Nishino, M., Fujita, N., Noda, T., Yamaguchi, A., Yoshimori, T. and Yamamoto, A. (2010) Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation. Autophagy 6, 301-303
-
(2010)
Autophagy
, vol.6
, pp. 301-303
-
-
Hayashi-Nishino, M.1
Fujita, N.2
Noda, T.3
Yamaguchi, A.4
Yoshimori, T.5
Yamamoto, A.6
-
14
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
Hailey, D.W., Rambold, A.S., Satpute-Krishnan, P., Mitra, K., Sougrat, R., Kim, P.K. and Lippincott-Schwartz, J. (2010) Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 141, 656-667
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
Rambold, A.S.2
Satpute-Krishnan, P.3
Mitra, K.4
Sougrat, R.5
Kim, P.K.6
Lippincott-Schwartz, J.7
-
15
-
-
71649112895
-
3D tomography reveals connections between the phagophore and endoplasmic reticulum
-
Ylau-Anttila, P., Vihinen, H., Jokitalo, E. and Eskelinen, E.L. (2009) 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 5, 1180-1185
-
(2009)
Autophagy
, vol.5
, pp. 1180-1185
-
-
Ylau-Anttila, P.1
Vihinen, H.2
Jokitalo, E.3
Eskelinen, E.L.4
-
16
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki, M., Furuta, N., Matsuda, A., Nezu, A., Yamamoto, A., Fujita, N., Oomori, H., Noda, T., Haraguchi, T., Hiraoka, Y. et al. (2013) Autophagosomes form at ER-mitochondria contact sites. Nature 495, 389-393
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
Nezu, A.4
Yamamoto, A.5
Fujita, N.6
Oomori, H.7
Noda, T.8
Haraguchi, T.9
Hiraoka, Y.10
-
17
-
-
77955131007
-
Plasma membrane contributes to the formation of pre-autophagosomal structures
-
Ravikumar, B., Moreau, K., Jahreiss, L., Puri, C. and Rubinsztein, D.C. (2010) Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat. Cell Biol. 12, 747-757
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.C.5
-
18
-
-
34447276502
-
Human WIPI-1 puncta-formation: A novel assay to assess mammalian autophagy
-
Proikas-Cezanne, T., Ruckerbauer, S., Stierhof, Y.D., Berg, C. and Nordheim, A. (2007) Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy. FEBS Lett. 581, 3396-3404
-
(2007)
FEBS Lett.
, vol.581
, pp. 3396-3404
-
-
Proikas-Cezanne, T.1
Ruckerbauer, S.2
Stierhof, Y.D.3
Berg, C.4
Nordheim, A.5
-
19
-
-
77953726483
-
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
-
Polson, H.E., de Lartigue, J., Rigden, D.J., Reedijk, M., Urbé, S., Clague, M.J. and Tooze, S.A. (2010) Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 6, 506-522
-
(2010)
Autophagy
, vol.6
, pp. 506-522
-
-
Polson, H.E.1
De Lartigue, J.2
Rigden, D.J.3
Reedijk, M.4
Urbé, S.5
Clague, M.J.6
Tooze, S.A.7
-
20
-
-
11244289333
-
WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
-
Proikas-Cezanne, T., Waddell, S., Gaugel, A., Frickey, T., Lupas, A. and Nordheim, A. (2004) WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy. Oncogene 23, 9314-9325
-
(2004)
Oncogene
, vol.23
, pp. 9314-9325
-
-
Proikas-Cezanne, T.1
Waddell, S.2
Gaugel, A.3
Frickey, T.4
Lupas, A.5
Nordheim, A.6
-
21
-
-
79953127788
-
Autophagosome formation in mammalian cells
-
Burman, C. and Ktistakis, N. (2010) Autophagosome formation in mammalian cells. Semin. Immunopathol. 32, 397-413
-
(2010)
Semin. Immunopathol.
, vol.32
, pp. 397-413
-
-
Burman, C.1
Ktistakis, N.2
-
23
-
-
84861614439
-
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
-
Abrahamsen, H., Stenmark, H. and Platta, H.W. (2012) Ubiquitination and phosphorylation of Beclin 1 and its binding partners: tuning class III phosphatidylinositol 3-kinase activity and tumor suppression. FEBS Lett. 586, 1584-1591
-
(2012)
FEBS Lett.
, vol.586
, pp. 1584-1591
-
-
Abrahamsen, H.1
Stenmark, H.2
Platta, H.W.3
-
24
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by Beclin 1
-
Liang, X.H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H. and Levine, B. (1999) Induction of autophagy and inhibition of tumorigenesis by Beclin 1. Nature 402, 672-676
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
25
-
-
77955895424
-
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
-
Matsunaga, K., Morita, E., Saitoh, T., Akira, S., Ktistakis, N.T., Izumi, T., Noda, T. and Yoshimori, T. (2010) Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J. Cell Biol. 190, 511-521
-
(2010)
J. Cell Biol.
, vol.190
, pp. 511-521
-
-
Matsunaga, K.1
Morita, E.2
Saitoh, T.3
Akira, S.4
Ktistakis, N.T.5
Izumi, T.6
Noda, T.7
Yoshimori, T.8
-
26
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang, C., Feng, P., Ku, B., Dotan, I., Canaani, D., Oh, B.H. and Jung, J.U. (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat. Cell Biol. 8, 688-699
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
Jung, J.U.7
-
27
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
Takahashi, Y., Coppola, D., Matsushita, N., Cualing, H.D., Sun, M., Sato, Y., Liang, C., Jung, J.U., Cheng, J.Q., Mulé, J.J. et al. (2007) Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat. Cell Biol. 9, 1142-1151
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
Sato, Y.6
Liang, C.7
Jung, J.U.8
Cheng, J.Q.9
Mulé, J.J.10
-
28
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Zhong, Y., Wang, Q.J., Li, X., Yan, Y., Backer, J.M., Chait, B.T., Heintz, N. and Yue, Z. (2009) Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat. Cell Biol. 11, 468-476
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
Heintz, N.7
Yue, Z.8
-
29
-
-
77952576359
-
Negative regulation of Vps34 by Cdk mediated phosphorylation
-
Furuya, T., Kim, M., Lipinski, M., Li, J., Kim, D., Lu, T., Shen, Y., Rameh, L., Yankner, B., Tsai, L.H. and Yuan, J. (2010) Negative regulation of Vps34 by Cdk mediated phosphorylation. Mol. Cell 38, 500-511
-
(2010)
Mol. Cell
, vol.38
, pp. 500-511
-
-
Furuya, T.1
Kim, M.2
Lipinski, M.3
Li, J.4
Kim, D.5
Lu, T.6
Shen, Y.7
Rameh, L.8
Yankner, B.9
Tsai, L.H.10
Yuan, J.11
-
30
-
-
84859573948
-
PKD is a kinase of Vps34 that mediates ROSinduced autophagy downstream of DAPk
-
Eisenberg-Lerner, A. and Kimchi, A. (2012) PKD is a kinase of Vps34 that mediates ROSinduced autophagy downstream of DAPk. Cell Death Differ. 19, 788-797
-
(2012)
Cell Death Differ.
, vol.19
, pp. 788-797
-
-
Eisenberg-Lerner, A.1
Kimchi, A.2
-
31
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine, B., Mizushima, N. and Virgin, H.W. (2011) Autophagy in immunity and inflammation. Nature 469, 323-335
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
32
-
-
33947715151
-
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
-
Orvedahl, A., Alexander, D., Tallóczy, Z., Sun, Q., Wei, Y., Zhang, W., Burns, D., Leib, D.A. and Levine, B. (2007) HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 1, 23-35
-
(2007)
Cell Host Microbe
, vol.1
, pp. 23-35
-
-
Orvedahl, A.1
Alexander, D.2
Tallóczy, Z.3
Sun, Q.4
Wei, Y.5
Zhang, W.6
Burns, D.7
Leib, D.A.8
Levine, B.9
-
33
-
-
80655124392
-
Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate
-
Cottam, E.M., Maier, H.J., Manifava, M., Vaux, L.C., Chandra- Schoenfelder, P., Gerner, W., Britton, P., Ktistakis, N.T. and Wileman, T. (2011) Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate. Autophagy 7, 1335-1347
-
(2011)
Autophagy
, vol.7
, pp. 1335-1347
-
-
Cottam, E.M.1
Maier, H.J.2
Manifava, M.3
Vaux, L.C.4
Chandra-Schoenfelder, P.5
Gerner, W.6
Britton, P.7
Ktistakis, N.T.8
Wileman, T.9
-
34
-
-
78650812302
-
Antibacterial autophagy occurs at PI(3)Penriched domains of the endoplasmic reticulum and requires Rab1 GTPase
-
Huang, J., Birmingham, C.L., Shahnazari, S., Shiu, J., Zheng, Y.T., Smith, A.C., Campellone, K.G., Heo, W.D., Gruenheid, S., Meyer, T. et al. (2011) Antibacterial autophagy occurs at PI(3)Penriched domains of the endoplasmic reticulum and requires Rab1 GTPase. Autophagy 7, 17-26
-
(2011)
Autophagy
, vol.7
, pp. 17-26
-
-
Huang, J.1
Birmingham, C.L.2
Shahnazari, S.3
Shiu, J.4
Zheng, Y.T.5
Smith, A.C.6
Campellone, K.G.7
Heo, W.D.8
Gruenheid, S.9
Meyer, T.10
-
35
-
-
77950505030
-
The role of PI3P phosphatases in the regulation of autophagy
-
Vergne, I. and Deretic, V. (2010) The role of PI3P phosphatases in the regulation of autophagy. FEBS Lett. 584, 1313-1318
-
(2010)
FEBS Lett.
, vol.584
, pp. 1313-1318
-
-
Vergne, I.1
Deretic, V.2
-
36
-
-
68249153748
-
Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy
-
Vergne, I., Roberts, E., Elmaoued, R.A., Tosch, V., Delgado, M.A., Proikas-Cezanne, T., Laporte, J. and Deretic, V. (2009) Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy. EMBO J. 28, 2244-2258
-
(2009)
EMBO J.
, vol.28
, pp. 2244-2258
-
-
Vergne, I.1
Roberts, E.2
Elmaoued, R.A.3
Tosch, V.4
Delgado, M.A.5
Proikas-Cezanne, T.6
Laporte, J.7
Deretic, V.8
-
37
-
-
77951708056
-
Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy
-
Taguchi-Atarashi, N., Hamasaki, M., Matsunaga, K., Omori, H., Ktistakis, N.T., Yoshimori, T. and Noda, T. (2010) Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy. Traffic 11, 468-478
-
(2010)
Traffic
, vol.11
, pp. 468-478
-
-
Taguchi-Atarashi, N.1
Hamasaki, M.2
Matsunaga, K.3
Omori, H.4
Ktistakis, N.T.5
Yoshimori, T.6
Noda, T.7
-
38
-
-
78650815265
-
What is the advantage of a transient precursor in autophagosome biogenesis
-
Ktistakis, N.T., Andrews, S. and Long, J. (2011) What is the advantage of a transient precursor in autophagosome biogenesis. Autophagy 7, 118-122
-
(2011)
Autophagy
, vol.7
, pp. 118-122
-
-
Ktistakis, N.T.1
Andrews, S.2
Long, J.3
|