메뉴 건너뛰기




Volumn 102, Issue , 2014, Pages 95-105

Experimental rhinovirus infection in COPD: Implications for antiviral therapies

Author keywords

Chronic obstructive pulmonary disease (COPD); Exacerbations; Respiratory viruses; Rhinovirus

Indexed keywords

ANTIVIRUS AGENT;

EID: 84892142574     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.12.006     Document Type: Review
Times cited : (27)

References (119)
  • 3
    • 84861466279 scopus 로고    scopus 로고
    • Exhaled eicosanoids and biomarkers of oxidative stress in exacerbation of chronic obstructive pulmonary disease
    • A. Antczak, M. Ciebiada, T. Pietras, W.J. Piotrowski, Z. Kurmanowska, and P. Gorski Exhaled eicosanoids and biomarkers of oxidative stress in exacerbation of chronic obstructive pulmonary disease Arch. Med. Sci. 8 2012 277 285
    • (2012) Arch. Med. Sci. , vol.8 , pp. 277-285
    • Antczak, A.1    Ciebiada, M.2    Pietras, T.3    Piotrowski, W.J.4    Kurmanowska, Z.5    Gorski, P.6
  • 4
    • 73449129243 scopus 로고    scopus 로고
    • Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes
    • A. Anzueto, I. Leimer, and S. Kesten Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes Int. J. Chron. Obstruct. Pulm. Dis. 4 2009 245 251
    • (2009) Int. J. Chron. Obstruct. Pulm. Dis. , vol.4 , pp. 245-251
    • Anzueto, A.1    Leimer, I.2    Kesten, S.3
  • 7
    • 84873265676 scopus 로고    scopus 로고
    • Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD
    • K.J. Baines, A.C. Hsu, M. Tooze, L.P. Gunawardhana, P.G. Gibson, and P.A. Wark Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD Respir. Res. 14 2013 15
    • (2013) Respir. Res. , vol.14 , pp. 15
    • Baines, K.J.1    Hsu, A.C.2    Tooze, M.3    Gunawardhana, L.P.4    Gibson, P.G.5    Wark, P.A.6
  • 9
    • 77954814658 scopus 로고    scopus 로고
    • Inhaled corticosteroids in COPD: A controversy
    • P.J. Barnes Inhaled corticosteroids in COPD: a controversy Respiration 80 2010 89 95
    • (2010) Respiration , vol.80 , pp. 89-95
    • Barnes, P.J.1
  • 12
    • 17344366818 scopus 로고    scopus 로고
    • Respiratory viral infections in patients with chronic, obstructive pulmonary disease
    • DOI 10.1016/j.jinf.2004.07.011, PII S0163445304001665
    • J.D. Beckham, A. Cadena, J. Lin, P.A. Piedra, W.P. Glezen, S.B. Greenberg, and R.L. Atmar Respiratory viral infections in patients with chronic, obstructive pulmonary disease J. Infect. 50 2005 322 330 (Pubitemid 40533369)
    • (2005) Journal of Infection , vol.50 , Issue.4 , pp. 322-330
    • Beckham, J.D.1    Cadena, A.2    Lin, J.3    Piedra, P.A.4    Glezen, W.P.5    Greenberg, S.B.6    Atmar, R.L.7
  • 13
    • 0034018102 scopus 로고    scopus 로고
    • Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations
    • DOI 10.1136/thorax.55.2.114
    • A. Bhowmik, T.A. Seemungal, R.J. Sapsford, and J.A. Wedzicha Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations Thorax 55 2000 114 120 (Pubitemid 30245950)
    • (2000) Thorax , vol.55 , Issue.2 , pp. 114-120
    • Bhowmik, A.1    Seemungal, T.A.R.2    Sapsford, R.J.3    Wedzicha, J.A.4
  • 14
    • 0345073628 scopus 로고    scopus 로고
    • Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD
    • DOI 10.1136/thorax.58.4.294
    • W.A. Biernacki, S.A. Kharitonov, and P.J. Barnes Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD Thorax 58 2003 294 298 (Pubitemid 36411413)
    • (2003) Thorax , vol.58 , Issue.4 , pp. 294-298
    • Biernacki, W.A.1    Kharitonov, S.A.2    Barnes, P.J.3
  • 15
    • 84860459038 scopus 로고    scopus 로고
    • Clinical and molecular features of human rhinovirus C
    • Y.A. Bochkov, and J.E. Gern Clinical and molecular features of human rhinovirus C Microbes Infect. 14 2012 485 494
    • (2012) Microbes Infect. , vol.14 , pp. 485-494
    • Bochkov, Y.A.1    Gern, J.E.2
  • 16
    • 84892152133 scopus 로고    scopus 로고
    • Effect of inhaled SNG001 (interferon-beta 1a) on sputum and blood antiviral biomarkers following a respiratory virus infection in asthmatic subjects
    • Abstract 4369
    • Boxall, C., Dudley, S., Beegan, R., Tear, V., Hrebien, S., Lunn, K., Monk, P., 2013. Effect of inhaled SNG001 (interferon-beta 1a) on sputum and blood antiviral biomarkers following a respiratory virus infection in asthmatic subjects. ERS Congress 2013. Abstract 4369.
    • (2013) ERS Congress 2013
    • Boxall, C.1    Dudley, S.2    Beegan, R.3    Tear, V.4    Hrebien, S.5    Lunn, K.6    Monk, P.7
  • 19
    • 0018097566 scopus 로고
    • Infections with viruses and Mycoplasma pneumonaiae during exacerbations of chronic bronchitis
    • R.O. Buscho, D. Saxtan, P.S. Shultz, E. Finch, and M.A. Mufson Infections with viruses and Mycoplasma pneumoniae during exacerbations of chronic bronchitis J. Infect. Dis. 137 1978 377 383 (Pubitemid 8327250)
    • (1978) Journal of Infectious Diseases , vol.137 , Issue.4 , pp. 377-383
    • Buscho, R.O.1    Saxtan, D.2    Shultz, P.S.3
  • 22
    • 33745442788 scopus 로고    scopus 로고
    • Virus infection in exacerbations of chronic obstructive pulmonary disease requiring ventilation
    • DOI 10.1007/s00134-006-0202-x
    • R.J. Cameron, D. de Wit, T.N. Welsh, J. Ferguson, T.V. Grissell, and P.J. Rye Virus infection in exacerbations of chronic obstructive pulmonary disease requiring ventilation Intensive Care Med. 32 2006 1022 1029 (Pubitemid 43952717)
    • (2006) Intensive Care Medicine , vol.32 , Issue.7 , pp. 1022-1029
    • Cameron, R.J.1    De Wit, D.2    Welsh, T.N.3    Ferguson, J.4    Grissell, T.V.5    Rye, P.J.6
  • 23
    • 84877603164 scopus 로고    scopus 로고
    • Inhaled corticosteroids in COPD: Quantifying risks and benefits
    • C. Cates Inhaled corticosteroids in COPD: quantifying risks and benefits Thorax 68 2013 499 500
    • (2013) Thorax , vol.68 , pp. 499-500
    • Cates, C.1
  • 25
    • 84877862567 scopus 로고    scopus 로고
    • Role of the Arylhydrocarbon Receptor (AhR) in the pathology of asthma and COPD
    • T. Chiba, J. Chihara, and M. Furue Role of the Arylhydrocarbon Receptor (AhR) in the pathology of asthma and COPD J. Allergy 2012 2012 372384
    • (2012) J. Allergy , vol.2012 , pp. 372384
    • Chiba, T.1    Chihara, J.2    Furue, M.3
  • 26
    • 1842671720 scopus 로고    scopus 로고
    • Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)
    • A.F. Connors Jr., N.V. Dawson, C. Thomas, F.E. Harrell Jr., N. Desbiens, W.J. Fulkerson, P. Kussin, P. Bellamy, L. Goldman, and W.A. Knaus Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments) Am. J. Respir. Crit. Care Med. 154 1996 959 967
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 959-967
    • Connors, Jr.A.F.1    Dawson, N.V.2    Thomas, C.3    Harrell, Jr.F.E.4    Desbiens, N.5    Fulkerson, W.J.6    Kussin, P.7    Bellamy, P.8    Goldman, L.9    Knaus, W.A.10
  • 29
    • 84859424158 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease
    • M. Decramer, W. Janssens, and M. Miravitlles Chronic obstructive pulmonary disease Lancet 379 2012 1341 1351
    • (2012) Lancet , vol.379 , pp. 1341-1351
    • Decramer, M.1    Janssens, W.2    Miravitlles, M.3
  • 34
    • 0036794862 scopus 로고    scopus 로고
    • Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
    • DOI 10.1136/thorax.57.10.847
    • G.C. Donaldson, T.A. Seemungal, A. Bhowmik, and J.A. Wedzicha Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease Thorax 57 2002 847 852 (Pubitemid 35178607)
    • (2002) Thorax , vol.57 , Issue.10 , pp. 847-852
    • Donaldson, G.C.1    Seemungal, T.A.R.2    Bhowmik, A.3    Wedzicha, J.A.4
  • 36
    • 16844364420 scopus 로고    scopus 로고
    • Oxidative stress and airway inflammation in severe exacerbations of COPD
    • DOI 10.1136/thx.2004.027946
    • E.M. Drost, K.M. Skwarski, J. Sauleda, N. Soler, J. Roca, A. Agusti, and W. MacNee Oxidative stress and airway inflammation in severe exacerbations of COPD Thorax 60 2005 293 300 (Pubitemid 40522365)
    • (2005) Thorax , vol.60 , Issue.4 , pp. 293-300
    • Drost, E.M.1    Skwarski, K.M.2    Sauleda, J.3    Soler, N.4    Roca, J.5    Agusti, A.6    MacNee, W.7
  • 40
    • 17244382260 scopus 로고    scopus 로고
    • Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease
    • DOI 10.1183/09031936.05.00047504
    • K. Fujimoto, M. Yasuo, K. Urushibata, M. Hanaoka, T. Koizumi, and K. Kubo Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease Eur. Respir. J. 25 2005 640 646 (Pubitemid 40528756)
    • (2005) European Respiratory Journal , vol.25 , Issue.4 , pp. 640-646
    • Fujimoto, K.1    Yasuo, M.2    Urushibata, K.3    Hanaoka, M.4    Koizumi, T.5    Kubo, K.6
  • 45
    • 0043234165 scopus 로고    scopus 로고
    • Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD
    • DOI 10.1378/chest.124.2.459
    • K.H. Groenewegen, A.M. Schols, and E.F. Wouters Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD Chest 124 2003 459 467 (Pubitemid 37000120)
    • (2003) Chest , vol.124 , Issue.2 , pp. 459-467
    • Groenewegen, K.H.1    Schols, A.M.W.J.2    Wouters, E.F.M.3
  • 47
    • 0020267625 scopus 로고
    • Prophylactic activity of intranasal enviroxime against experimentally induced rhinovirus type 39 infection
    • F.G. Hayden, and J.M. Gwaltney Jr. Prophylactic activity of intranasal enviroxime against experimentally induced rhinovirus type 39 infection Antimicrob. Agents Chemother. 21 1982 892 897 (Pubitemid 12012603)
    • (1982) Antimicrobial Agents and Chemotherapy , vol.21 , Issue.6 , pp. 892-897
    • Hayden, F.G.1    Gwaltney Jr., J.M.2
  • 48
    • 0021279737 scopus 로고
    • 2 treatment of experimental rhinoviral colds
    • F.G. Hayden, and J.M. Gwaltney Jr. Intranasal interferon-alpha 2 treatment of experimental rhinoviral colds J. Infect. Dis. 150 1984 174 180 (Pubitemid 14073356)
    • (1984) Journal of Infectious Diseases , vol.150 , Issue.2 , pp. 174-180
    • Hayden, F.G.1    Gwaltney Jr., J.M.2
  • 49
    • 0023813222 scopus 로고
    • Modification of experimental rhinovirus colds by receptor blockade
    • F.G. Hayden, J.M. Gwaltney Jr., and R.J. Colonno Modification of experimental rhinovirus colds by receptor blockade Antivir. Res. 9 1988 233 247
    • (1988) Antivir. Res. , vol.9 , pp. 233-247
    • Hayden, F.G.1    Gwaltney, Jr.J.M.2    Colonno, R.J.3
  • 50
    • 0026520723 scopus 로고
    • Safety and efficacy of intranasal pirodavir (R77975) in experimental rhinovirus infection
    • F.G. Hayden, K. Andries, and P.A. Janssen Safety and efficacy of intranasal pirodavir (R77975) in experimental rhinovirus infection Antimicrob. Agents Chemother. 36 1992 727 732
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 727-732
    • Hayden, F.G.1    Andries, K.2    Janssen, P.A.3
  • 53
    • 0344012008 scopus 로고    scopus 로고
    • Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers
    • DOI 10.1128/AAC.47.12.3907-3916.2003
    • F.G. Hayden, R.B. Turner, J.M. Gwaltney, K. Chi-Burris, M. Gersten, P. Hsyu, A.K. Patick, G.J. Smith 3rd, and L.S. Zalman Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers Antimicrob.Agents Chemother. 47 2003 3907 3916 (Pubitemid 37485007)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.12 , pp. 3907-3916
    • Hayden, F.G.1    Turner, R.B.2    Gwaltney, J.M.3    Chi-Burris, K.4    Gersten, M.5    Hsyu, P.6    Patick, A.K.7    Smith III, G.J.8    Zalman, L.S.9
  • 54
    • 66149093072 scopus 로고    scopus 로고
    • The pathology of chronic obstructive pulmonary disease
    • J.C. Hogg, and W. Timens The pathology of chronic obstructive pulmonary disease Ann. Rev. Pathol. 4 2009 435 459
    • (2009) Ann. Rev. Pathol. , vol.4 , pp. 435-459
    • Hogg, J.C.1    Timens, W.2
  • 55
    • 27744452381 scopus 로고    scopus 로고
    • Epidemiological relationships between the common cold and exacerbation frequency in COPD
    • DOI 10.1183/09031936.05.00043405
    • J.R. Hurst, G.C. Donaldson, T.M.A. Wilkinson, W.R. Perera, and J.A. Wedzicha Epidemiological relationships between the common cold and exacerbation frequency in COPD Eur. Respir. J. 26 2005 846 852 (Pubitemid 41632041)
    • (2005) European Respiratory Journal , vol.26 , Issue.5 , pp. 846-852
    • Hurst, J.R.1    Donaldson, G.C.2    Wilkinson, T.M.A.3    Perera, W.R.4    Wedzicha, J.A.5
  • 61
    • 0035422691 scopus 로고    scopus 로고
    • 1 decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: Results from the Lung Health Study
    • R.E. Kanner, N.R. Anthonisen, and J.E. Connett Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study Am. J. Respir. Crit. Care Med. 164 2001 358 364 (Pubitemid 32778199)
    • (2001) American Journal of Respiratory and Critical Care Medicine , vol.164 , Issue.3 , pp. 358-364
    • Kanner, R.E.1    Anthonisen, N.R.2    Connett, J.E.3
  • 69
    • 84872660131 scopus 로고    scopus 로고
    • COPD exacerbations: Causes, prevention, and treatment
    • A.J. Mackay, and J.R. Hurst COPD exacerbations: causes, prevention, and treatment Immunol. Allergy Clin. North Am. 33 2013 95 115
    • (2013) Immunol. Allergy Clin. North Am. , vol.33 , pp. 95-115
    • Mackay, A.J.1    Hurst, J.R.2
  • 70
    • 33749184326 scopus 로고    scopus 로고
    • An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: A pilot study
    • P. Mallia, S.D. Message, T. Kebadze, H.L. Parker, O.M. Kon, and S.L. Johnston An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study Respir. Res. 7 2006 116
    • (2006) Respir. Res. , vol.7 , pp. 116
    • Mallia, P.1    Message, S.D.2    Kebadze, T.3    Parker, H.L.4    Kon, O.M.5    Johnston, S.L.6
  • 75
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • C.D. Mathers, and D. Loncar Projections of global mortality and burden of disease from 2002 to 2030 PLoS Med. 3 2006 e442
    • (2006) PLoS Med. , vol.3 , pp. 442
    • Mathers, C.D.1    Loncar, D.2
  • 77
    • 28044444899 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): A prevalence study
    • DOI 10.1016/S0140-6736(05)67632-5, PII S0140673605676325
    • A.M. Menezes, R. Perez-Padilla, J.R. Jardim, A. Muino, M.V. Lopez, G. Valdivia, M. Montes de Oca, C. Talamo, P.C. Hallal, and C.G. Victora Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study Lancet 366 2005 1875 1881 (Pubitemid 41690116)
    • (2005) Lancet , vol.366 , Issue.9500 , pp. 1875-1881
    • Menezes, A.M.B.1    Perez-Padilla, R.2    Jardim, J.R.B.3    Muino, A.4    Lopez, M.V.5    Valdivia, G.6    De Oca, M.M.7    Talamo, C.8    Hallal, P.C.9    Victora, C.G.10
  • 81
    • 0026746409 scopus 로고
    • Bacterial infection in chronic obstructive pulmonary disease
    • T.F. Murphy, and S. Sethi Bacterial infection in chronic obstructive pulmonary disease Am. Rev. Respir. Dis. 146 1992 1067 1083
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 1067-1083
    • Murphy, T.F.1    Sethi, S.2
  • 83
    • 65649122592 scopus 로고    scopus 로고
    • Airway inflammation and anti-protease defences rapidly improve during treatment of an acute exacerbation of COPD
    • S. Pant, E.H. Walters, A. Griffiths, R. Wood-Baker, D.P. Johns, and D.W. Reid Airway inflammation and anti-protease defences rapidly improve during treatment of an acute exacerbation of COPD Respirology (Carlton, Vic.) 14 2009 495 503
    • (2009) Respirology (Carlton, Vic.) , vol.14 , pp. 495-503
    • Pant, S.1    Walters, E.H.2    Griffiths, A.3    Wood-Baker, R.4    Johns, D.P.5    Reid, D.W.6
  • 85
    • 84859317909 scopus 로고    scopus 로고
    • Acute exacerbations of COPD in the United States: Inpatient burden and predictors of costs and mortality
    • P.N. Perera, E.P. Armstrong, D.L. Sherrill, and G.H. Skrepnek Acute exacerbations of COPD in the United States: inpatient burden and predictors of costs and mortality COPD 9 2012 131 141
    • (2012) COPD , vol.9 , pp. 131-141
    • Perera, P.N.1    Armstrong, E.P.2    Sherrill, D.L.3    Skrepnek, G.H.4
  • 86
    • 84875660026 scopus 로고    scopus 로고
    • Detection of multiple viral and bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: A pilot prospective study
    • J.M. Perotin, S. Dury, F. Renois, G. Deslee, A. Wolak, V. Duval, C. De Champs, F. Lebargy, and L. Andreoletti Detection of multiple viral and bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: a pilot prospective study J. Med. Virol. 85 2013 866 873
    • (2013) J. Med. Virol. , vol.85 , pp. 866-873
    • Perotin, J.M.1    Dury, S.2    Renois, F.3    Deslee, G.4    Wolak, A.5    Duval, V.6    De Champs, C.7    Lebargy, F.8    Andreoletti, L.9
  • 90
    • 0037253901 scopus 로고    scopus 로고
    • Respiratory viruses in exacerbations of chronic obstructive pulmonary disease requiring hospitalisation: A case-control study
    • DOI 10.1136/thorax.58.1.37
    • G. Rohde, A. Wiethege, I. Borg, M. Kauth, T.T. Bauer, A. Gillissen, A. Bufe, and G. Schultze-Werninghaus Respiratory viruses in exacerbations of chronic obstructive pulmonary disease requiring hospitalisation: a case-control study Thorax 58 2003 37 42 (Pubitemid 36135356)
    • (2003) Thorax , vol.58 , Issue.1 , pp. 37-42
    • Rohde, G.1    Wiethege, A.2    Borg, I.3    Kauth, M.4    Bauer, T.T.5    Gillissen, A.6    Bufe, A.7    Schultze-Werninghaus, G.8
  • 92
    • 0035155262 scopus 로고    scopus 로고
    • Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease
    • DOI 10.1136/thorax.56.1.30
    • M. Roland, A. Bhowmik, R.J. Sapsford, T.A. Seemungal, D.J. Jeffries, T.D. Warner, and J.A. Wedzicha Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease Thorax 56 2001 30 35 (Pubitemid 32041716)
    • (2001) Thorax , vol.56 , Issue.1 , pp. 30-35
    • Roland, M.1    Bhowmik, A.2    Sapsford, R.J.3    Seemungal, T.A.R.4    Jeffries, D.J.5    Warner, T.D.6    Wedzicha, J.A.7
  • 95
    • 0033955181 scopus 로고    scopus 로고
    • Clinical activity of pleconaril in an experimentally induced coxsackievirus A21 respiratory infection
    • DOI 10.1086/315176
    • G.M. Schiff, and J.R. Sherwood Clinical activity of pleconaril in an experimentally induced coxsackievirus A21 respiratory infection J. Infect. Dis. 181 2000 20 26 (Pubitemid 30049028)
    • (2000) Journal of Infectious Diseases , vol.181 , Issue.1 , pp. 20-26
    • Schiff, G.M.1    Sherwood, J.R.2
  • 99
    • 0033773356 scopus 로고    scopus 로고
    • Detection of rhinovirus in induced sputum at exacerbation of chronic obstructive pulmonary disease
    • T.A. Seemungal, R. Harper-Owen, A. Bhowmik, D.J. Jeffries, and J.A. Wedzicha Detection of rhinovirus in induced sputum at exacerbation of chronic obstructive pulmonary disease Eur. Respir. J. 16 2000 677 683
    • (2000) Eur. Respir. J. , vol.16 , pp. 677-683
    • Seemungal, T.A.1    Harper-Owen, R.2    Bhowmik, A.3    Jeffries, D.J.4    Wedzicha, J.A.5
  • 101
    • 0036580905 scopus 로고    scopus 로고
    • FDA panel rejects common cold treatment
    • K. Senior FDA panel rejects common cold treatment Lancet Infect. Dis. 2 2002 264
    • (2002) Lancet Infect. Dis. , vol.2 , pp. 264
    • Senior, K.1
  • 102
    • 79953795292 scopus 로고    scopus 로고
    • Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease
    • S. Sethi Molecular diagnosis of respiratory tract infection in acute exacerbations of chronic obstructive pulmonary disease Clin. Infect. Dis. 52 Suppl. 4 2011 S290 S295
    • (2011) Clin. Infect. Dis. , vol.52 , Issue.SUPPL. 4
    • Sethi, S.1
  • 103
    • 77956695581 scopus 로고    scopus 로고
    • Inhaled corticosteroids and risk of pneumonia: Evidence for and against the proposed association
    • A. Singanayagam, J.D. Chalmers, and A.T. Hill Inhaled corticosteroids and risk of pneumonia: evidence for and against the proposed association QJM 103 2010 379 385
    • (2010) QJM , vol.103 , pp. 379-385
    • Singanayagam, A.1    Chalmers, J.D.2    Hill, A.T.3
  • 105
    • 0018827121 scopus 로고
    • Association of viral and Mycoplasma pneumoniae infections with acute respiratory illness in patients with chronic obstructive pulmonary diseases
    • C.B. Smith, C.A. Golden, R.E. Kanner, and A.D. Renzetti Jr. Association of viral and Mycoplasma pneumoniae infections with acute respiratory illness in patients with chronic obstructive pulmonary diseases Am. Rev. Respir. Dis. 121 1980 225 232 (Pubitemid 10095215)
    • (1980) American Review of Respiratory Disease , vol.121 , Issue.2 , pp. 225-232
    • Smith, C.B.1    Golden, C.A.2    Kanner, R.E.3    Renzetti Jr., A.D.4
  • 106
    • 33846311358 scopus 로고    scopus 로고
    • Antibiotic treatment of exacerbations of COPD: A randomized, controlled trial comparing procalcitonin-guidance with standard therapy
    • DOI 10.1378/chest.06-1500
    • D. Stolz, M. Christ-Crain, R. Bingisser, J. Leuppi, D. Miedinger, C. Muller, P. Huber, B. Muller, and M. Tamm Antibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapy Chest 131 2007 9 19 (Pubitemid 46122969)
    • (2007) Chest , vol.131 , Issue.1 , pp. 9-19
    • Stolz, D.1    Christ-Grain, M.2    Bingisser, R.3    Leuppi, J.4    Miedinger, D.5    Muller, C.6    Huber, P.7    Muller, B.8    Tamm, M.9
  • 107
    • 69249124565 scopus 로고    scopus 로고
    • Inhaled corticosteroids in COPD: The case against
    • S. Suissa, and P.J. Barnes Inhaled corticosteroids in COPD: the case against Eur. Respir. J. 34 2009 13 16
    • (2009) Eur. Respir. J. , vol.34 , pp. 13-16
    • Suissa, S.1    Barnes, P.J.2
  • 108
    • 0041377790 scopus 로고    scopus 로고
    • Epidemiology of respiratory viruses in patients hospitalized with near-fatal asthma, acute exacerbations of asthma, or chronic obstructive pulmonary disease
    • DOI 10.1016/S0002-9343(03)00353-X
    • W.C. Tan, X. Xiang, D. Qiu, T.P. Ng, S.F. Lam, and R.G. Hegele Epidemiology of respiratory viruses in patients hospitalized with near-fatal asthma, acute exacerbations of asthma, or chronic obstructive pulmonary disease Am. J. Med. 115 2003 272 277 (Pubitemid 37088188)
    • (2003) American Journal of Medicine , vol.115 , Issue.4 , pp. 272-277
    • Tan, W.C.1    Xiang, X.2    Qiu, D.3    Ng, T.P.4    Lam, S.F.5    Hegele, R.G.6
  • 110
    • 21844476459 scopus 로고    scopus 로고
    • Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD
    • M. Tsoumakidou, N. Tzanakis, G. Chrysofakis, and N.M. Siafakas Nitrosative stress, heme oxygenase-1 expression and airway inflammation during severe exacerbations of COPD Chest 127 2005 1911 1918
    • (2005) Chest , vol.127 , pp. 1911-1918
    • Tsoumakidou, M.1    Tzanakis, N.2    Chrysofakis, G.3    Siafakas, N.M.4
  • 113
    • 2942517739 scopus 로고    scopus 로고
    • Markers of inflammation and oxidative stress during lower respiratory tract infections in COPD patiets
    • Van Beurden, W.J., Smeenk, F.W., Harff, G.A., Dekhuijzen, P.N., 2003. Markers of inflammation and oxidative stress during lower respiratory tract infections in COPD patients. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace/Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Universita di Napoli, Secondo ateneo 59, 273-280. (Pubitemid 38745284)
    • (2003) Monaldi Archives for Chest Disease - Pulmonary Series , vol.59 , Issue.4 , pp. 273-280
    • Van Beurden, W.J.C.1    Smeenk, F.W.J.M.2    Harff, G.A.3    Dekhuijzen, P.N.R.4
  • 118
    • 56049106616 scopus 로고    scopus 로고
    • Antibiotics at COPD exacerbations: The debate continues
    • J.A. Wedzicha Antibiotics at COPD exacerbations: the debate continues Thorax 63 2008 940 942
    • (2008) Thorax , vol.63 , pp. 940-942
    • Wedzicha, J.A.1
  • 119
    • 37849011194 scopus 로고    scopus 로고
    • The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
    • Investigators I.
    • J.A. Wedzicha, P.M. Calverley, T.A. Seemungal, G. Hagan, Z. Ansari, R.A. Stockley, and I. Investigators The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide Am. J. Respir. Crit. Care Med. 177 2008 19 26
    • (2008) Am. J. Respir. Crit. Care Med. , vol.177 , pp. 19-26
    • Wedzicha, J.A.1    Calverley, P.M.2    Seemungal, T.A.3    Hagan, G.4    Ansari, Z.5    Stockley, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.