Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Thorax

Volumn 56, Issue 1, 2001, Pages 30-35

  Roland, M ^a   Bhowmik, A ^a   Sapsford, R J ^a   Seemungal, T A R ^a   Jeffries, D J ^a   Warner, T D ^a   Wedzicha, J A ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease; Cytokines; Endothelin 1; Inflammation; Sputum

Indexed keywords

ENDOTHELIN 1; INTERLEUKIN 6; INTERLEUKIN 8;

ADULT; AGED; ARTICLE; CHLAMYDOPHILA PNEUMONIAE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE EXACERBATION; FORCED EXPIRATORY VOLUME; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; OXYGEN SATURATION; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RHINOVIRUS; SPUTUM LEVEL;

AGED; BIOLOGICAL MARKERS; CHLAMYDOPHILA PNEUMONIAE; CONFIDENCE INTERVALS; CYTOKINES; ENDOTHELIN-1; FORCED EXPIRATORY VOLUME; HUMANS; LUNG DISEASES, OBSTRUCTIVE; PROSPECTIVE STUDIES; RHINOVIRUS; SPUTUM; VITAL CAPACITY;

EID: 0035155262     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.56.1.30     Document Type: Article

References (36)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. Endothelin in bronchoalveolar lavage fluid and its relation to airflow obstruction in asthma
3. Putative mediator role of endothelin-1 in asthma and other lung diseases
4. Endothelin-1 induces GM-CSF, IL-6 and IL-8 but not G-CSF release from a human bronchial epithelial cell line (BEAS-2B)
5. Endothelin immunoreactivity of airway epithelium in asthmatic patients
6. Nitric oxide and endothelin-1 in pulmonary hypertension
7. Endothelins, peptides with potent vasoactive properties, are produced by human macrophages
8. Endothelial cell responses to hypoxic stress
9. Distribution of immunoreactive endothelin in the lungs of mice during respiratory viral infection
10. What turns on the endothelins?
11. Sputum endothelin-1 is increased in cystic fibrosis and chronic obstructive pulmonary disease
12. Increased 24-hour endothelin-1 urinary excretion in patients with chronic obstructive pulmonary disease
13. Detection of rhinovirus in induced sputum at exacerbations of chronic obstructive pulmonary disease
14. Role of infection in chronic bronchitis
15. Virus and chlamydia isolation in COPD exacerbation
16. guidelines for the management of chronic obstructive pulmonary disease
17. Arterialised ear lobe blood gas analysis: An underused technique
18. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease
19. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease
20. Comparison of spontaneous and induced sputum for investigation of airway inflammation in chronic obstructive pulmonary disease
21. Use of induced sputum cell counts to investigate airway inflammation in asthma
22. The activity of peptides of the endothelin family in various mammalian smooth muscle preparations
23. Use of polyrnerase chain reaction for diagnosis of picornavirus infection in subjects with and without respiratory symptoms
24. Chronic chlamydia pneumoniae infection and asthma exacerbations in children
25. Endothelin-1-induced bronchoconstriction in asthma
26. Increased expression of endothelin in bronchial epithelial cells of asthmatic patients and effect of corticostereoids
27. Endotoxin and proinflammatory cytokines stimulate endothelin-1 expression and release by airway epithelial cells
28. Endothelin-1 levels in induced sputum samples from asthmatic and normal subjects
29. Oral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary disease: A prospective randomised controlled trial
30. Pathophysiology of endothelin in the cardiovascular system
31. Endothelin production and effects of endothelin antagonism during experimental airway inflammation
32. Rhinovirus-16 colds in healthy and in asthmatic subjects
33. Airway obstruction, chronic expectoration and rapid decline in FEV in smokers are associated with increased levels of sputum neutrophils
34. Acute respiratory tract infections and risk of first-time acute myocardial infarction
35. Symptoms of chronic bronchitis and the risk of coronary disease
36. Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevation of plasma fibrinogen and serum IL-6 levels