Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia

Haematologica

Volumn 98, Issue 8, 2013, Pages 1173-1184

  Larmonie, Nicole S D ^a   Dik, Willem A ^a   Meijerink, Jules P P ^b   Homminga, Irene ^b   van Dongen, Jacques J M ^a   Langerak, Anton W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; BMI1 PROTEIN; BREAKPOINT CLUSTER REGION PROTEIN; LIM KINASE 1; NOTCH1 RECEPTOR; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TAL1;

ACUTE LYMPHOBLASTIC LEUKEMIA; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; DNA REPAIR; GENE LOCUS; GENE REARRANGEMENT; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOMIC INSTABILITY; HUMAN; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; ONCOGENE MYB; ONCOGENE MYC; REVIEW; TRANSCRIPTION INITIATION SITE; VDJ RECOMBINATION;

ANIMALS; CHROMOSOME BREAKPOINTS; HUMANS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, ANTIGEN, T-CELL; V(D)J RECOMBINATION;

EID: 84880993951     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.082156     Document Type: Review

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