메뉴 건너뛰기




Volumn 8, Issue 12, 2013, Pages

The prognostic value of Phosphorylated AKT expression in non-small cell lung cancer: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B;

EID: 84891917101     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081451     Document Type: Article
Times cited : (21)

References (33)
  • 2
    • 79952306961 scopus 로고    scopus 로고
    • The prognostic value of RASSF1A promoter hypermethylation in non-small cell lung carcinoma: A systematic review and meta-analysis
    • doi:10.1093/carcin/bgq266. PubMed: 21156971
    • Wang J, Wang B, Chen X, Bi J (2011) The prognostic value of RASSF1A promoter hypermethylation in non-small cell lung carcinoma: a systematic review and meta-analysis. Carcinogenesis 32:411-416. doi:10.1093/carcin/bgq266. PubMed: 21156971.
    • (2011) Carcinogenesis , vol.32 , pp. 411-416
    • Wang, J.1    Wang, B.2    Chen, X.3    Bi, J.4
  • 3
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I, Sawyers CL (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2:489-501. doi:10.1038/nrc839. PubMed: 12094235. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 4
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer PJ, Jin J, Woodgett JR (1998) Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 335(1):1-13. PubMed: 9742206. (Pubitemid 28477043)
    • (1998) Biochemical Journal , vol.335 , Issue.1 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 5
    • 0001582482 scopus 로고
    • Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
    • DOI 10.1073/pnas.84.14.5034
    • Staal SP (1987) Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc Natl Acad Sci U S A 84:5034-5037. doi:10.1073/pnas.84.14. 5034. PubMed: 3037531. (Pubitemid 17095859)
    • (1987) Proceedings of the National Academy of Sciences of the United States of America , vol.84 , Issue.14 , pp. 5034-5037
    • Staal, S.P.1
  • 7
    • 0031936947 scopus 로고    scopus 로고
    • Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
    • DOI 10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R
    • Ruggeri BA, Huang L, Wood M, Cheng JQ, Testa JR (1998) Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas. Mol Carcinog 21:81-86. doi:10.1002/(SICI) 1098-2744 (199802) 21:2. PubMed: 9496907. (Pubitemid 28122842)
    • (1998) Molecular Carcinogenesis , vol.21 , Issue.2 , pp. 81-86
    • Ruggeri, B.A.1    Huang, L.2    Wood, M.3    Cheng, J.Q.4    Testa, J.R.5
  • 11
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • doi:10.1038/21224. PubMed: 10376603
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R et al. (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601-605. doi:10.1038/21224. PubMed: 10376603.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5
  • 12
    • 0037093274 scopus 로고    scopus 로고
    • Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer
    • Nakanishi K, Sakamoto M, Yasuda J, Takamura M, Fujita N et al. (2002) Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. Cancer Res 62:2971-2975. PubMed: 12019180. (Pubitemid 34525787)
    • (2002) Cancer Research , vol.62 , Issue.10 , pp. 2971-2975
    • Nakanishi, K.1    Sakamoto, M.2    Yasuda, J.3    Takamura, M.4    Fujita, N.5    Tsuruo, T.6    Todo, S.7    Hirohashi, S.8
  • 13
    • 84885951502 scopus 로고    scopus 로고
    • The prognostic value of MGMT promoter methylation in Glioblastoma multiforme: A metaanalysis
    • Zhang K, Wang XQ, Zhou B, Zhang L (2013) The prognostic value of MGMT promoter methylation in Glioblastoma multiforme: a metaanalysis. Fam. Cancer.
    • (2013) Fam. Cancer
    • Zhang, K.1    Wang, X.Q.2    Zhou, B.3    Zhang, L.4
  • 14
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0. CO;2-8
    • Parmar MK, Torri V, Stewart L (1998) Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 17:2815-2834. doi:10.1002/(SICI) 1097-0258 (19981230) 17:24. PubMed: 9921604. (Pubitemid 28562978)
    • (1998) Statistics in Medicine , vol.17 , Issue.24 , pp. 2815-2834
    • Parmar, M.K.B.1    Torri, V.2    Stewart, L.3
  • 15
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH (1997) Quantitative synthesis in systematic reviews. Ann Intern Med 127:820-826. doi: 10.7326/0003-4819-127-9- 199711010-00008. PubMed: 9382404. (Pubitemid 27465551)
    • (1997) Annals of Internal Medicine , vol.127 , Issue.9 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.A.2    Schmid, C.H.3
  • 16
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a metaanalysis
    • doi:10.1002/sim.1186. PubMed: 12111919
    • Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a metaanalysis. Stat Med 21:1539-1558. doi:10.1002/sim.1186. PubMed: 12111919.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 17
    • 6044230919 scopus 로고    scopus 로고
    • Phospho-Akt overexpression in non-small cell lung cancer confers significant stage-independent survival disadvantage
    • DOI 10.1158/1078-0432.CCR-04-0174
    • David O, Jett J, LeBeau H, Dy G, Hughes J, et al. (2004) Phospho-Akt overexpression in non-small cell lung cancer confers significant stageindependent survival disadvantage. Clin Cancer Res 10:6865-6871. (Pubitemid 39383035)
    • (2004) Clinical Cancer Research , vol.10 , Issue.20 , pp. 6865-6871
    • David, O.1    Jett, J.2    LeBeau, H.3    Dy, G.4    Hughes, J.5    Friedman, M.6    Brody, A.R.7
  • 20
    • 33845944849 scopus 로고    scopus 로고
    • Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma
    • DOI 10.1016/j.lungcan.2006.09.026, PII S0169500206005277
    • Tsurutani J, Steinberg SM, Ballas M, Robertson M, LoPiccolo J et al. (2007) Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma. Lung Cancer 55:115-121. doi:10.1016/j.lungcan. 2006.09.026. PubMed: 17097759. (Pubitemid 46038882)
    • (2007) Lung Cancer , vol.55 , Issue.1 , pp. 115-121
    • Tsurutani, J.1    Steinberg, S.M.2    Ballas, M.3    Robertson, M.4    LoPiccolo, J.5    Soda, H.6    Kohno, S.7    Egilsson, V.8    Dennis, P.A.9
  • 21
    • 74949114784 scopus 로고    scopus 로고
    • Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer
    • doi:10.1158/1078-0432. CCR-09-0986. PubMed: 20008839
    • Yoshizawa A, Fukuoka J, Shimizu S, Shilo K, Franks TJ et al. (2010) Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer. Clin Cancer Res 16:240-248. doi:10.1158/1078- 0432. CCR-09-0986. PubMed: 20008839.
    • (2010) Clin Cancer Res , vol.16 , pp. 240-248
    • Yoshizawa, A.1    Fukuoka, J.2    Shimizu, S.3    Shilo, K.4    Franks, T.J.5
  • 22
    • 77955375157 scopus 로고    scopus 로고
    • The expression and clinical significance of AKT2, phosphorylated AKT2 in non-small cell lung cancer
    • PubMed: 20848774
    • Pu R, Li WM, Liu D, Mo XM, Tang Y et al. (2010) The expression and clinical significance of AKT2, phosphorylated AKT2 in non-small cell lung cancer. Sichuan da Xue Xue Bao Yi Xue Ban 41:586-589. PubMed: 20848774.
    • (2010) Sichuan da Xue Xue Bao Yi Xue Ban , vol.41 , pp. 586-589
    • Pu, R.1    Li, W.M.2    Liu, D.3    Mo, X.M.4    Tang, Y.5
  • 23
    • 80051479542 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma
    • doi:10.1002/cncr.25959. PubMed: 21387259
    • Liu D, Huang Y, Chen B, Zeng J, Guo N et al. (2011) Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma. Cancer 117:3763-3773. doi:10.1002/cncr.25959. PubMed: 21387259.
    • (2011) Cancer , vol.117 , pp. 3763-3773
    • Liu, D.1    Huang, Y.2    Chen, B.3    Zeng, J.4    Guo, N.5
  • 24
    • 84862655352 scopus 로고    scopus 로고
    • Combinations of laminin 5 with PTEN, p-EGFR and p-Akt define a group of distinct molecular subsets indicative of poor prognosis in patients with nonsmall cell lung cancer
    • PubMed: 23139712
    • An SJ, Lin QX, Chen ZH, Su J, Cheng H et al. (2012) Combinations of laminin 5 with PTEN, p-EGFR and p-Akt define a group of distinct molecular subsets indicative of poor prognosis in patients with nonsmall cell lung cancer. Exp Ther Med 4:226-230. PubMed: 23139712.
    • (2012) Exp Ther Med , vol.4 , pp. 226-230
    • An, S.J.1    Lin, Q.X.2    Chen, Z.H.3    Su, J.4    Cheng, H.5
  • 26
    • 0035008874 scopus 로고    scopus 로고
    • Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
    • DOI 10.1128/MCB.21.6.2203-2212.2001
    • Hutchinson J, Jin J, Cardiff RD, Woodgett JR, Muller WJ (2001) Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol 21:2203-2212. doi:10.1128/MCB.21.6.2203-2212.2001. PubMed: 11238953. (Pubitemid 32479640)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.6 , pp. 2203-2212
    • Hutchinson, J.1    Jin, J.2    Cardiff, R.D.3    Woodgett, J.R.4    Muller, W.J.5
  • 27
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
    • doi:10.1074/jbc. M010840200. PubMed: 11139588
    • Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S et al. (2001) Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 276:9817-9824. doi:10.1074/jbc. M010840200. PubMed: 11139588.
    • (2001) J Biol Chem , vol.276 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5
  • 28
    • 0032534025 scopus 로고    scopus 로고
    • The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70(s6k)-dependent pathway
    • Moore SM, Rintoul RC, Walker TR, Chilvers ER, Haslett C et al. (1998) The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway. Cancer Res 58:5239-5247. PubMed: 9823338. (Pubitemid 28521188)
    • (1998) Cancer Research , vol.58 , Issue.22 , pp. 5239-5247
    • Moore, S.M.1    Rintoul, R.C.2    Walker, T.R.3    Chilvers, E.R.4    Haslett, C.5    Sethi, T.6
  • 29
    • 0035872199 scopus 로고    scopus 로고
    • Akt/pbotein kinace B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • Brognard J, Clark AS, Ni Y, Dennis PA (2001) Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 61:3986-3997. PubMed: 11358816. (Pubitemid 32720961)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3    Dennis, P.A.4
  • 31
    • 0037304479 scopus 로고    scopus 로고
    • Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma
    • DOI 10.1016/S0022-5347(05)63998-5
    • Horiguchi A, Oya M, Uchida A, Marumo K, Murai M (2003) Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma. J Urol 169:710-713. doi:10.1016/S0022-5347 (05) 63998-5. PubMed: 12544348. (Pubitemid 36133028)
    • (2003) Journal of Urology , vol.169 , Issue.2 , pp. 710-713
    • Horiguchi, A.1    Oya, M.2    Uchida, A.3    Marumo, K.4    Murai, M.5
  • 33
    • 84891956610 scopus 로고    scopus 로고
    • Clinical significance of EGFR gene mutations and Expression of Downstream Phosphorylated Signal Transduction Proteins AKT and ERK protein expression in Non-Small Cell Lung Carcinoma
    • Cheng YH, Zhang CF (2011) Clinical significance of EGFR gene mutations and Expression of Downstream Phosphorylated Signal Transduction Proteins AKT and ERK protein expression in Non-Small Cell Lung Carcinoma. Master's degree thesis
    • (2011) Master's Degree Thesis
    • Cheng, Y.H.1    Zhang, C.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.