-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55:74-108. doi:10.3322/canjclin. 55.2.74. PubMed: 15761078. (Pubitemid 40372904)
-
(2005)
Ca-A Cancer Journal for Clinicians
, vol.55
, Issue.2
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
79952306961
-
The prognostic value of RASSF1A promoter hypermethylation in non-small cell lung carcinoma: A systematic review and meta-analysis
-
doi:10.1093/carcin/bgq266. PubMed: 21156971
-
Wang J, Wang B, Chen X, Bi J (2011) The prognostic value of RASSF1A promoter hypermethylation in non-small cell lung carcinoma: a systematic review and meta-analysis. Carcinogenesis 32:411-416. doi:10.1093/carcin/bgq266. PubMed: 21156971.
-
(2011)
Carcinogenesis
, vol.32
, pp. 411-416
-
-
Wang, J.1
Wang, B.2
Chen, X.3
Bi, J.4
-
3
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2:489-501. doi:10.1038/nrc839. PubMed: 12094235. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
4
-
-
0032189381
-
Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
-
Coffer PJ, Jin J, Woodgett JR (1998) Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 335(1):1-13. PubMed: 9742206. (Pubitemid 28477043)
-
(1998)
Biochemical Journal
, vol.335
, Issue.1
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
5
-
-
0001582482
-
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
-
DOI 10.1073/pnas.84.14.5034
-
Staal SP (1987) Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc Natl Acad Sci U S A 84:5034-5037. doi:10.1073/pnas.84.14. 5034. PubMed: 3037531. (Pubitemid 17095859)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.14
, pp. 5034-5037
-
-
Staal, S.P.1
-
6
-
-
0036094711
-
Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival
-
Ermoian RP, Furniss CS, Lamborn KR, Basila D, Berger MS et al. (2002) Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. Clin Cancer Res 8:1100-1106. PubMed: 12006525. (Pubitemid 34517646)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.5
, pp. 1100-1106
-
-
Ermoian, R.P.1
Furniss, C.S.2
Lamborn, K.R.3
Basila, D.4
Berger, M.S.5
Gottschalk, A.R.6
Nicholas, M.K.7
Stokoe, D.8
Haas-Kogan, D.A.9
-
7
-
-
0031936947
-
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
-
DOI 10.1002/(SICI)1098-2744(199802)21:2<81::AID-MC1>3.0.CO;2-R
-
Ruggeri BA, Huang L, Wood M, Cheng JQ, Testa JR (1998) Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas. Mol Carcinog 21:81-86. doi:10.1002/(SICI) 1098-2744 (199802) 21:2. PubMed: 9496907. (Pubitemid 28122842)
-
(1998)
Molecular Carcinogenesis
, vol.21
, Issue.2
, pp. 81-86
-
-
Ruggeri, B.A.1
Huang, L.2
Wood, M.3
Cheng, J.Q.4
Testa, J.R.5
-
8
-
-
0036554734
-
Immunohistochemical demonstration of phospho-Akt in high gleason grade prostate cancer
-
Malik SN, Brattain M, Ghosh PM, Troyer DA, Prihoda T et al. (2002) Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. Clin Cancer Res 8:1168-1171. PubMed: 11948129. (Pubitemid 35177371)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.4
, pp. 1168-1171
-
-
Malik, S.N.1
Brattain, M.2
Ghosh, P.M.3
Troyer, D.A.4
Prihoda, T.5
Bedolla, R.6
Kreisberg, J.I.7
-
9
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF et al. (1998) Regulation of cell death protease caspase-9 by phosphorylation. Science 282:1318-1321. doi:10.1126/science.282.5392.1318. PubMed: 9812896. (Pubitemid 28524494)
-
(1998)
Science
, vol.282
, Issue.5392
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
10
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96:857-868. doi:10.1016/S0092-8674 (00) 80595-4. PubMed: 10102273. (Pubitemid 29165088)
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
11
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
doi:10.1038/21224. PubMed: 10376603
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R et al. (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601-605. doi:10.1038/21224. PubMed: 10376603.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
-
12
-
-
0037093274
-
Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer
-
Nakanishi K, Sakamoto M, Yasuda J, Takamura M, Fujita N et al. (2002) Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. Cancer Res 62:2971-2975. PubMed: 12019180. (Pubitemid 34525787)
-
(2002)
Cancer Research
, vol.62
, Issue.10
, pp. 2971-2975
-
-
Nakanishi, K.1
Sakamoto, M.2
Yasuda, J.3
Takamura, M.4
Fujita, N.5
Tsuruo, T.6
Todo, S.7
Hirohashi, S.8
-
13
-
-
84885951502
-
The prognostic value of MGMT promoter methylation in Glioblastoma multiforme: A metaanalysis
-
Zhang K, Wang XQ, Zhou B, Zhang L (2013) The prognostic value of MGMT promoter methylation in Glioblastoma multiforme: a metaanalysis. Fam. Cancer.
-
(2013)
Fam. Cancer
-
-
Zhang, K.1
Wang, X.Q.2
Zhou, B.3
Zhang, L.4
-
14
-
-
0032583387
-
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
-
DOI 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0. CO;2-8
-
Parmar MK, Torri V, Stewart L (1998) Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 17:2815-2834. doi:10.1002/(SICI) 1097-0258 (19981230) 17:24. PubMed: 9921604. (Pubitemid 28562978)
-
(1998)
Statistics in Medicine
, vol.17
, Issue.24
, pp. 2815-2834
-
-
Parmar, M.K.B.1
Torri, V.2
Stewart, L.3
-
15
-
-
0030693603
-
Quantitative synthesis in systematic reviews
-
Lau J, Ioannidis JP, Schmid CH (1997) Quantitative synthesis in systematic reviews. Ann Intern Med 127:820-826. doi: 10.7326/0003-4819-127-9- 199711010-00008. PubMed: 9382404. (Pubitemid 27465551)
-
(1997)
Annals of Internal Medicine
, vol.127
, Issue.9
, pp. 820-826
-
-
Lau, J.1
Ioannidis, J.P.A.2
Schmid, C.H.3
-
16
-
-
0037098199
-
Quantifying heterogeneity in a metaanalysis
-
doi:10.1002/sim.1186. PubMed: 12111919
-
Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a metaanalysis. Stat Med 21:1539-1558. doi:10.1002/sim.1186. PubMed: 12111919.
-
(2002)
Stat Med
, vol.21
, pp. 1539-1558
-
-
Higgins, J.P.1
Thompson, S.G.2
-
17
-
-
6044230919
-
Phospho-Akt overexpression in non-small cell lung cancer confers significant stage-independent survival disadvantage
-
DOI 10.1158/1078-0432.CCR-04-0174
-
David O, Jett J, LeBeau H, Dy G, Hughes J, et al. (2004) Phospho-Akt overexpression in non-small cell lung cancer confers significant stageindependent survival disadvantage. Clin Cancer Res 10:6865-6871. (Pubitemid 39383035)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.20
, pp. 6865-6871
-
-
David, O.1
Jett, J.2
LeBeau, H.3
Dy, G.4
Hughes, J.5
Friedman, M.6
Brody, A.R.7
-
18
-
-
4444332925
-
Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer
-
Cappuzzo F, Magrini E, Ceresoli GL, Bartolini S, Rossi E et al. (2004) Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 96:1133-1141. doi: 10.1093/jnci/djh217. PubMed: 15292385. (Pubitemid 39207049)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.15
, pp. 1133-1141
-
-
Cappuzzo, F.1
Magrini, E.2
Ceresoli, G.L.3
Bartolini, S.4
Rossi, E.5
Ludovini, V.6
Gregorc, V.7
Ligorio, C.8
Cancellieri, A.9
Damiani, S.10
Spreafico, A.11
Paties, C.T.12
Lombardo, L.13
Calandri, C.14
Bellezza, G.15
Tonato, M.16
Crino, L.17
-
19
-
-
20244376768
-
Phospho-Akt expression is associated with a favorable outcome in non-small cell lung cancer
-
DOI 10.1158/1078-0432.CCR-04-1385
-
Shah A, Swain WA, Richardson D, Edwards J, Stewart DJ et al. (2005) Phospho-akt expression is associated with a favorable outcome in nonsmall cell lung cancer. Clin Cancer Res 11:2930-2936. doi: 10.1158/1078-0432. CCR-04-1385. PubMed: 15837744. (Pubitemid 40525195)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.8
, pp. 2930-2936
-
-
Shah, A.1
Swain, W.A.2
Richardson, D.3
Edwards, J.4
Stewart, D.J.5
Richardson, C.M.6
Swinson, D.E.B.7
Patel, D.8
Jones, J.L.9
O'Byrne, K.J.10
-
20
-
-
33845944849
-
Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma
-
DOI 10.1016/j.lungcan.2006.09.026, PII S0169500206005277
-
Tsurutani J, Steinberg SM, Ballas M, Robertson M, LoPiccolo J et al. (2007) Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma. Lung Cancer 55:115-121. doi:10.1016/j.lungcan. 2006.09.026. PubMed: 17097759. (Pubitemid 46038882)
-
(2007)
Lung Cancer
, vol.55
, Issue.1
, pp. 115-121
-
-
Tsurutani, J.1
Steinberg, S.M.2
Ballas, M.3
Robertson, M.4
LoPiccolo, J.5
Soda, H.6
Kohno, S.7
Egilsson, V.8
Dennis, P.A.9
-
21
-
-
74949114784
-
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer
-
doi:10.1158/1078-0432. CCR-09-0986. PubMed: 20008839
-
Yoshizawa A, Fukuoka J, Shimizu S, Shilo K, Franks TJ et al. (2010) Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer. Clin Cancer Res 16:240-248. doi:10.1158/1078- 0432. CCR-09-0986. PubMed: 20008839.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 240-248
-
-
Yoshizawa, A.1
Fukuoka, J.2
Shimizu, S.3
Shilo, K.4
Franks, T.J.5
-
22
-
-
77955375157
-
The expression and clinical significance of AKT2, phosphorylated AKT2 in non-small cell lung cancer
-
PubMed: 20848774
-
Pu R, Li WM, Liu D, Mo XM, Tang Y et al. (2010) The expression and clinical significance of AKT2, phosphorylated AKT2 in non-small cell lung cancer. Sichuan da Xue Xue Bao Yi Xue Ban 41:586-589. PubMed: 20848774.
-
(2010)
Sichuan da Xue Xue Bao Yi Xue Ban
, vol.41
, pp. 586-589
-
-
Pu, R.1
Li, W.M.2
Liu, D.3
Mo, X.M.4
Tang, Y.5
-
23
-
-
80051479542
-
Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma
-
doi:10.1002/cncr.25959. PubMed: 21387259
-
Liu D, Huang Y, Chen B, Zeng J, Guo N et al. (2011) Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma. Cancer 117:3763-3773. doi:10.1002/cncr.25959. PubMed: 21387259.
-
(2011)
Cancer
, vol.117
, pp. 3763-3773
-
-
Liu, D.1
Huang, Y.2
Chen, B.3
Zeng, J.4
Guo, N.5
-
24
-
-
84862655352
-
Combinations of laminin 5 with PTEN, p-EGFR and p-Akt define a group of distinct molecular subsets indicative of poor prognosis in patients with nonsmall cell lung cancer
-
PubMed: 23139712
-
An SJ, Lin QX, Chen ZH, Su J, Cheng H et al. (2012) Combinations of laminin 5 with PTEN, p-EGFR and p-Akt define a group of distinct molecular subsets indicative of poor prognosis in patients with nonsmall cell lung cancer. Exp Ther Med 4:226-230. PubMed: 23139712.
-
(2012)
Exp Ther Med
, vol.4
, pp. 226-230
-
-
An, S.J.1
Lin, Q.X.2
Chen, Z.H.3
Su, J.4
Cheng, H.5
-
25
-
-
0033152165
-
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
-
Davies MA, Koul D, Dhesi H, Berman R, McDonnell TJ et al. (1999) Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res 59:2551-2556. PubMed: 10363971. (Pubitemid 29269096)
-
(1999)
Cancer Research
, vol.59
, Issue.11
, pp. 2551-2556
-
-
Davies, M.A.1
Koul, D.2
Dhesi, H.3
Berman, R.4
McDonnell, T.J.5
McConkey, D.6
Yung, W.K.A.7
Steck, P.A.8
-
26
-
-
0035008874
-
Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
-
DOI 10.1128/MCB.21.6.2203-2212.2001
-
Hutchinson J, Jin J, Cardiff RD, Woodgett JR, Muller WJ (2001) Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol 21:2203-2212. doi:10.1128/MCB.21.6.2203-2212.2001. PubMed: 11238953. (Pubitemid 32479640)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.6
, pp. 2203-2212
-
-
Hutchinson, J.1
Jin, J.2
Cardiff, R.D.3
Woodgett, J.R.4
Muller, W.J.5
-
27
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
-
doi:10.1074/jbc. M010840200. PubMed: 11139588
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S et al. (2001) Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 276:9817-9824. doi:10.1074/jbc. M010840200. PubMed: 11139588.
-
(2001)
J Biol Chem
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
-
28
-
-
0032534025
-
The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70(s6k)-dependent pathway
-
Moore SM, Rintoul RC, Walker TR, Chilvers ER, Haslett C et al. (1998) The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway. Cancer Res 58:5239-5247. PubMed: 9823338. (Pubitemid 28521188)
-
(1998)
Cancer Research
, vol.58
, Issue.22
, pp. 5239-5247
-
-
Moore, S.M.1
Rintoul, R.C.2
Walker, T.R.3
Chilvers, E.R.4
Haslett, C.5
Sethi, T.6
-
29
-
-
0035872199
-
Akt/pbotein kinace B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
-
Brognard J, Clark AS, Ni Y, Dennis PA (2001) Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 61:3986-3997. PubMed: 11358816. (Pubitemid 32720961)
-
(2001)
Cancer Research
, vol.61
, Issue.10
, pp. 3986-3997
-
-
Brognard, J.1
Clark, A.S.2
Ni, Y.3
Dennis, P.A.4
-
30
-
-
0041846604
-
473) expression in bronchial dysplasia: Implications for lung cancer prevention studies
-
Tsao AS, McDonnell T, Lam S, Putnam JB, Bekele N et al. (2003) Increased phospho-AKT (Ser (473)) expression in bronchial dysplasia: implications for lung cancer prevention studies. Cancer Epidemiol Biomarkers Prev 12:660-664. PubMed: 12869408. (Pubitemid 36899849)
-
(2003)
Cancer Epidemiology Biomarkers and Prevention
, vol.12
, Issue.7
, pp. 660-664
-
-
Tsao, A.S.1
McDonnell, T.2
Lam, S.3
Putnam, J.B.4
Bekele, N.5
Hong, W.K.6
Kurie, J.M.7
-
31
-
-
0037304479
-
Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma
-
DOI 10.1016/S0022-5347(05)63998-5
-
Horiguchi A, Oya M, Uchida A, Marumo K, Murai M (2003) Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma. J Urol 169:710-713. doi:10.1016/S0022-5347 (05) 63998-5. PubMed: 12544348. (Pubitemid 36133028)
-
(2003)
Journal of Urology
, vol.169
, Issue.2
, pp. 710-713
-
-
Horiguchi, A.1
Oya, M.2
Uchida, A.3
Marumo, K.4
Murai, M.5
-
32
-
-
18244391514
-
Activation of Akt/PKB in breast cancer predicts a worse outcome among endocrine treated patients
-
DOI 10.1038/sj.bjc.6600126
-
Pérez-Tenorio G, Stål O (2002) Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients. Br J Cancer 86:540-545. doi:10.1038/sj.bjc.6600126. PubMed: 11870534. (Pubitemid 34185089)
-
(2002)
British Journal of Cancer
, vol.86
, Issue.4
, pp. 540-545
-
-
Perez-Tenorio, G.1
Stal, O.2
Arnesson, L.G.3
Malmstrom, A.4
Nordenskjold, B.5
Nordenskjold, K.6
Ba, H.7
Kallstrom, A.Ch.8
Einarsson, E.9
Norberg, B.10
Skoog, P.11
Henning, A.12
Sundquist, M.13
Tejler, G.14
-
33
-
-
84891956610
-
Clinical significance of EGFR gene mutations and Expression of Downstream Phosphorylated Signal Transduction Proteins AKT and ERK protein expression in Non-Small Cell Lung Carcinoma
-
Cheng YH, Zhang CF (2011) Clinical significance of EGFR gene mutations and Expression of Downstream Phosphorylated Signal Transduction Proteins AKT and ERK protein expression in Non-Small Cell Lung Carcinoma. Master's degree thesis
-
(2011)
Master's Degree Thesis
-
-
Cheng, Y.H.1
Zhang, C.F.2
|