Prion infection impairs cholesterol metabolism in neuronal cells

Journal of Biological Chemistry

Volumn 289, Issue 2, 2014, Pages 789-802

  Cui, Huanhuan L ^a,b   Guo, Belinda ^b   Scicluna, Benjamin ^b   Coleman, Bradley M ^b   Lawson, Victoria A ^c   Ellett, Laura ^c   Meikle, Peter J ^a   Bukrinsky, Michael ^d   Mukhamedova, Nigora ^a   Sviridov, Dmitri ^a   Hill, Andrew F ^b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b Molecular Science and Biotechnology Institute   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL METABOLISM; NEURONAL CELL; PRION DISEASE;

NEURODEGENERATIVE DISEASES;

CHOLESTEROL;

ABC TRANSPORTER A1; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID STORAGE; NERVE CELL; NONHUMAN; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ABC TRANSPORTER; CHOLESTEROL; LIPID RAFT; NEURODEGENERATIVE DISEASES; PRIONS;

3T3 CELLS; ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BLOTTING, WESTERN; BRAIN; CELL LINE; CELL LINE, TUMOR; CHOLESTEROL; ENDOSOMES; GENE EXPRESSION; HUMANS; HYDROCARBONS, FLUORINATED; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; NEURONS; PRION DISEASES; PRPSC PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SULFONAMIDES;

EID: 84891908669     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.535807     Document Type: Article

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